The structural relationship of phorbol and cortisol: A possible mechanism for the tumor promoting activity of phorbol

Summary The crucial functional groups of phorbol-12-myristate-13-acetate (PMA) are superimposable with those of the glucocorticoid cortisol in a unique manner which suggests a mechanism for PMA activity, i.e. the alkylation of a cortisol receptor.     

The suppression of mouse spontaneous locomotor activity by the ingestion of deuterium oxide.

The spontaneous locomotor activity of the laboratory mouse is significantly depressed by the ingestion of deuterium oxide. The response, which is reversible, is a retilinear one with up to 70% reduction in activity with the administration of 25% heavy water.     

Effect of heat treatment on the ATPase activity of various sarcoplasmic reticulum preparations.

Ca2+-stimulated ATPase activity of sarcoplasmic reticulum (SR) preparations is activated after a short period of preincubation at temperatures between 40 and 45 degrees C, but for temperatures higher than 48 degrees C pronounced denaturation is observed. Heat denaturation is decreased if Mg2+ or K+ are present during heat treatment.     

Organization of myosin molecules in the muscle thick filament

Summary Tryptic treatment of muscle thick filaments reveals the underlying backbones of aggregatedl-meromyosin as a coli of 3 secondary filaments (helical repeat 130 nm) each in turn a coli of a 3 finer ones.     

Blood plasma investigations by resonance raman spectroscopy: Detection of carotenoid pigments

Summary Using Raman spectroscopy, we demonstrate that low levels of -carotene, lycopene, and xanthophyll give rise to resonance enhanced bands in blood plasma. These results explain the significance of previously unidentified spectral maxima which have been related to the state of health of the blood donor.     

红毛五加多糖的分离纯化和表观分子质量测定

红毛五加经热水浸提，用Sevag法脱蛋白，经DEAE—cellulose 32离子交换层析和Sephacryl S-200HR凝胶层析纯化得到3个主要多糖组分：AHP-Ⅰ、AHP-Ⅱ、AHP-Ⅲ，经HPLC和Sephacryl S-300HR凝胶层析鉴定，3种多糖均为均一组分，HPLC测定AHP-Ⅰ、AHP-Ⅱ、AHP-Ⅲ的表观分子质量分别为：7．0kD、59．5kD和12．9kD，Sephacryl S-300HR凝胶层析进行验证，得到相似结果．     

基于生态足迹模型的贵州可持续发展能力定量评价

定量测度可持续发展能力是目前可持续发展研究的重要课题和前沿领域．其核心是确定人类是否生存于生态系统的承载力范围内．本文介绍了Wackemagel M等1996年以来提出和发展的可持续发展的定量测度方法——生态足迹法，并运用此方法计算和分析了贵州省2001年的生态足迹．其生态足迹由三个部分组成：1)生物资源；2)能源消费；3)贸易调整．按照这种方法计算，贵州省2001年人均生态足迹为1．49525hm^2，人均生态足迹赤字为1．153433hm^2．反映出目前贵州的生产、生活强度已经超过了生态系统的承载能力，区域生态系统处于人类的过度开发利用和压力之下．在此基础上作者提出了提高贵州省可持续发展能力的途径，最后还讨论了方法本身存在的一些缺陷．     

高校毕业生工作状况跟踪调查分析研究 --以江西医学院本科毕业生为例

通过邮寄问卷(用人单位问卷、毕业生问卷)，开展针对江西医学院本科毕业生临床工作状况的跟踪调查．以期了解该校毕业生在岗工作状况及用人单位、毕业生对教育、教学、管理工作的评价和建议，以进一步推动高等医学院校教学改革．促进教育、教学质量的全面提高。