手指口述安全管理方法的探讨

大多数煤矿生产事故是由于人的不安全行为造成的,通过执行"手指口述"方法,可以使员工对自己的操作行为以及作业环境的安全状态进行确认,通过提高员工自主管理和互助保安意识,保证操作过程安全可靠,消除生产事故隐患,从而可以提高安全管理水平,促进矿井安全生产.     

Genome sequence and analysis of the tuber crop potato

Potato (Solanum tuberosum L.) is the world's most important non-grain food crop and is central to global food security. It is clonally propagated, highly heterozygous, autotetraploid, and suffers acute inbreeding depression. Here we use a homozygous doubled-monoploid potato clone to sequence and assemble 86% of the 844-megabase genome. We predict 39,031 protein-coding genes and present evidence for at least two genome duplication events indicative of a palaeopolyploid origin. As the first genome sequence of an asterid, the potato genome reveals 2,642 genes specific to this large angiosperm clade. We also sequenced a heterozygous diploid clone and show that gene presence/absence variants and other potentially deleterious mutations occur frequently and are a likely cause of inbreeding depression. Gene family expansion, tissue-specific expression and recruitment of genes to new pathways contributed to the evolution of tuber development. The potato genome sequence provides a platform for genetic improvement of this vital crop.     

高海拔地区室内富氧浓度安全试验研究

室内富氧可以改善人在高海拔地区的缺氧状况,同时也会带来火灾危险,室内富氧的安全控制已成为重要的研究课题.文章对高海拔地区室内环境富氧条件下滤纸的燃烧速度和安全富氧浓度上限进行了试验研究,并对高海拔地区的富氧安全问题进行了分析.结果表明,在不同海拔地区,室内环境维持相同的氧分压时,滤纸的燃烧速度会随着海拔的升高而显著增加,如果不考虑当地的海拔高度而只以氧分压作为参考会带来火灾危险,但存在富氧的安全氧浓度上限,该氧浓度上限值与环境压力的关系为Y=27.91×exp(-P/44.78)+20.09;海拔不同,富氧到安全氧浓度上限时所对应的相当海拔也不同,该相当海拔与实际海拔的关系为H’=-0.68841+0.63893H+0.0048H2;在海拔高度低于5.55km的地区,通过对室内环境富氧可以安全地将相当海拔降低到3km以下.     

The Effectiveness of Structural Monetary Policy and Macro-Prudential Policies — Based on the DSGE Model That Includes Bank Heterogeneous Credit

Journal of Systems Science and Complexity - Structural monetary policy and macro-prudential policies are important parts of the policy system of the People’s Bank of China. By constructing a...     

弹性半空间-理想流体层中Stoneley波的动力特性

为了解弹性半空一理想流体层中Stoneley波的动力特性,并为进一步开发利用海洋资源提供调查方法,根据弹性固体与理想流体动力学方程,推导了弹性半空间一理想流体层中Stoneley波的特征方程、基于该特征方程,分析了固液两介质的物理特性对流体动压力的影响,以及固体和流体介质的位移分布情况．结果表明,该体系中Stoneley波在固体中的位移分布类似于半空间Rayleigh波,而在流体中的位移分布有明显的规律性;弹性半空一理想流体层中Stoneley波具有频散性,且其波速小于弹性半空间中Rayleigh波的波速．     

基于协方差矩阵的主动学习方法及应用研究

由于工业过程采集的数据中常包含大量的无标签样本,而有标签样本数量少且人工标记成本较高,因此,提出一种基于协方差矩阵的主动学习方法。利用有标签样本建立高斯过程回归模型,并构建无标签样本之间的协方差矩阵,以协方差矩阵行列式的值作为评价指标。在挑选信息量较大的无标签样本的同时,衡量样本间的相似性,避免样本的冗余添加,最终在相同标记代价下提升模型预测精度。基于工业过程数据进行算法的应用仿真,验证了所提方法的可行性和有效性。     

圆形加速器平衡轨道的计算

使用有限差分法,对方程中的非线性部分做泰勒展开,将其中的一次项和二次项都移至方程左端,对一次项直接离散,二次项进行半隐式处理,采用多层网格法外推方案,只需要很小的计算量就可以得到准确的解.将计算结果与龙格-库塔法以及传统的近似解析法做了比较,磁场调变度较小时三种方法符合很好.当磁场调变度变大时,传统的近似解析法由于未考虑非线性效应呈现出较大的误差,本方法具有更高的精度.本方法可用于计算磁场调变度很大的圆形加速器(例如固定磁场交变梯度加速器)的粒子平衡轨道.     

基于分时双频的高频地波雷达海面目标探测

提出了一种分时双频方法用以提高其目标探测性能.分析了分时双频雷达波形,针对分时双频探测引起的目标相干积累时间减少以及多普勒谱点不对齐等问题,利用非均匀傅里叶变换将其转换为一不适定问题,并利用Cauchy-Gaussian模型正则化方法进行外推处理,从而获得目标多普勒谱图.仿真结果表明该方法能够有效地消除海面移动目标的检测盲区,提高检测性能.     

应力比对脆性材料断裂影响及应变断裂准则验证

应用材料破坏分析软件MFPA2D(material failure process analysis),模拟了平面应力下双向应力比不断变化条件下脆性材料的不同破坏失稳过程,并以玻璃为例,重点研究了其在复杂应力状态下不同双向应力比对脆性材料裂纹扩展和断裂的影响. 研究结果表明,裂纹失稳扩展时的应力强度因子值随着双向应力比的升高而升高. 该结果证明双向应力确实对脆性材料的断裂韧性有影响. 理论分析得出的应变失效准则与数值模拟研究结果及试验结果的比较研究表明,应变失效准则作为脆性材料在双向应力下的断裂准则是可行的.     

Granzyme B is recovered by natural killer cells via clathrin-dependent endocytosis

When they recognize a target cell, natural killer (NK) cells mount an attack to kill the target by exerting their cytotoxicity via the exocytosis of cytotoxic granules. Although the details of this process (which includes the movement of cytotoxic granules in the immune synapse and their fusion with the plasma membrane, releasing granzymes and perforin into the synaptic cleft) are relatively better understood, the post-exocytosis regulation of the process is still largely unknown. Here we show that a clathrin-dependent endocytosis stimulated by target cell occurs in NK92 cell line, which is closely correlated with granzyme B recovery. Inhibition of the endocytosis significantly attenuates the cytotoxicity of NK92 cells. The NK cell recovery of its released effector molecules, in turn, suggests that endocytosis may well play a key role in the post exocytosis regulation of immune cells.