Chaos-assisted capture of irregular moons

It has been thought that the capture of irregular moons--with non-circular orbits--by giant planets occurs by a process in which they are first temporarily trapped by gravity inside the planet's Hill sphere (the region where planetary gravity dominates over solar tides). The capture of the moons is then made permanent by dissipative energy loss (for example, gas drag) or planetary growth. But the observed distributions of orbital inclinations, which now include numerous newly discovered moons, cannot be explained using current models. Here we show that irregular satellites are captured in a thin spatial region where orbits are chaotic, and that the resulting orbit is either prograde or retrograde depending on the initial energy. Dissipation then switches these long-lived chaotic orbits into nearby regular (non-chaotic) zones from which escape is impossible. The chaotic layer therefore dictates the final inclinations of the captured moons. We confirm this with three-dimensional Monte Carlo simulations that include nebular drag, and find good agreement with the observed inclination distributions of irregular moons at Jupiter and Saturn. In particular, Saturn has more prograde irregular moons than Jupiter, which we can explain as a result of the chaotic prograde progenitors being more efficiently swept away from Jupiter by its galilean moons.     

Superconductors: time-reversal symmetry breaking?

One of the mysteries of modern condensed-matter physics is the nature of the pseudogap state of the superconducting cuprates. Kaminski et al. claim to have observed signatures of time-reversal symmetry breaking in the pseudogap regime in underdoped Bi2Sr2CaCu2O8+delta (Bi2212). Here we argue that the observed circular dichroism is due to the 51 superstructure replica of the electronic bands and therefore cannot be considered as evidence for spontaneous time-reversal symmetry breaking in cuprates.     

刚性沉水植物影响下波浪传播及泥沙悬浮数值模拟

由于植物引起的紊动作用,含刚性植物床面中悬浮泥沙浓度与无植物裸床相比显著增加,而通过平均流速计算底床切应力的传统泥沙模型无法模拟出该现象。因此,在含植物水流水沙运动物理模型试验的基础上,构建了基于Flow–3D的含刚性沉水植物条件下波浪传播的三维数学模型,模拟了植物影响下波浪动力特征和泥沙悬浮过程,同时从紊动能角度修正希尔兹数,对泥沙模块进行了改进。与实测数据相比,该模型可较精确地模拟出植物引起的整体水流流速减小和局部冠层顶部处的流速增大、水体紊动增强以及紊动能在波周期内出现两个峰值的现象。与原始泥沙模块相比,改进的模型考虑了植物尾流紊动对泥沙运动的影响,可提高含植物床面泥沙悬浮模拟的精度。     

Retromalisus damzeni,gen. et sp. nov., a second Baltic amber taxon of the extinct family Berendtimiridae (Insecta: Coleoptera)

ABSTRACT

A second Baltic amber taxon, Retromalisus damzeni, gen. et sp. nov., is discovered in the previously monotypic extinct family Berendtimiridae. The morphological portrait of Berendtimiridae is complemented with the data on the structure of prosternum and abdomen.     

Generation of functional multipotent adult stem cells from GPR125+ germline progenitors

Adult mammalian testis is a source of pluripotent stem cells. However, the lack of specific surface markers has hampered identification and tracking of the unrecognized subset of germ cells that gives rise to multipotent cells. Although embryonic-like cells can be derived from adult testis cultures after only several weeks in vitro, it is not known whether adult self-renewing spermatogonia in long-term culture can generate such stem cells as well. Here, we show that highly proliferative adult spermatogonial progenitor cells (SPCs) can be efficiently obtained by cultivation on mitotically inactivated testicular feeders containing CD34+ stromal cells. SPCs exhibit testicular repopulating activity in vivo and maintain the ability in long-term culture to give rise to multipotent adult spermatogonial-derived stem cells (MASCs). Furthermore, both SPCs and MASCs express GPR125, an orphan adhesion-type G-protein-coupled receptor. In knock-in mice bearing a GPR125-beta-galactosidase (LacZ) fusion protein under control of the native Gpr125 promoter (GPR125-LacZ), expression in the testis was detected exclusively in spermatogonia and not in differentiated germ cells. Primary GPR125-LacZ SPC lines retained GPR125 expression, underwent clonal expansion, maintained the phenotype of germline stem cells, and reconstituted spermatogenesis in busulphan-treated mice. Long-term cultures of GPR125+ SPCs (GSPCs) also converted into GPR125+ MASC colonies. GPR125+ MASCs generated derivatives of the three germ layers and contributed to chimaeric embryos, with concomitant downregulation of GPR125 during differentiation into GPR125- cells. MASCs also differentiated into contractile cardiac tissue in vitro and formed functional blood vessels in vivo. Molecular bookmarking by GPR125 in the adult mouse and, ultimately, in the human testis could enrich for a population of SPCs for derivation of GPR125+ MASCs, which may be employed for genetic manipulation, tissue regeneration and revascularization of ischaemic organs.     

Revisiting Lévy flight search patterns of wandering albatrosses, bumblebees and deer

The study of animal foraging behaviour is of practical ecological importance, and exemplifies the wider scientific problem of optimizing search strategies. Lévy flights are random walks, the step lengths of which come from probability distributions with heavy power-law tails, such that clusters of short steps are connected by rare long steps. Lévy flights display fractal properties, have no typical scale, and occur in physical and chemical systems. An attempt to demonstrate their existence in a natural biological system presented evidence that wandering albatrosses perform Lévy flights when searching for prey on the ocean surface. This well known finding was followed by similar inferences about the search strategies of deer and bumblebees. These pioneering studies have triggered much theoretical work in physics (for example, refs 11, 12), as well as empirical ecological analyses regarding reindeer, microzooplankton, grey seals, spider monkeys and fishing boats. Here we analyse a new, high-resolution data set of wandering albatross flights, and find no evidence for Lévy flight behaviour. Instead we find that flight times are gamma distributed, with an exponential decay for the longest flights. We re-analyse the original albatross data using additional information, and conclude that the extremely long flights, essential for demonstrating Lévy flight behaviour, were spurious. Furthermore, we propose a widely applicable method to test for power-law distributions using likelihood and Akaike weights. We apply this to the four original deer and bumblebee data sets, finding that none exhibits evidence of Lévy flights, and that the original graphical approach is insufficient. Such a graphical approach has been adopted to conclude Lévy flight movement for other organisms, and to propose Lévy flight analysis as a potential real-time ecosystem monitoring tool. Our results question the strength of the empirical evidence for biological Lévy flights.     

Mitochondrial aspartyl-tRNA synthetase deficiency causes leukoencephalopathy with brain stem and spinal cord involvement and lactate elevation

Leukoencephalopathy with brain stem and spinal cord involvement and lactate elevation (LBSL) has recently been defined based on a highly characteristic constellation of abnormalities observed by magnetic resonance imaging and spectroscopy. LBSL is an autosomal recessive disease, most often manifesting in early childhood. Affected individuals develop slowly progressive cerebellar ataxia, spasticity and dorsal column dysfunction, sometimes with a mild cognitive deficit or decline. We performed linkage mapping with microsatellite markers in LBSL families and found a candidate region on chromosome 1, which we narrowed by means of shared haplotypes. Sequencing of genes in this candidate region uncovered mutations in DARS2, which encodes mitochondrial aspartyl-tRNA synthetase, in affected individuals from all 30 families. Enzyme activities of mutant proteins were decreased. We were surprised to find that activities of mitochondrial complexes from fibroblasts and lymphoblasts derived from affected individuals were normal, as determined by different assays.