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231.
Summary The crucial functional groups of phorbol-12-myristate-13-acetate (PMA) are superimposable with those of the glucocorticoid cortisol in a unique manner which suggests a mechanism for PMA activity, i.e. the alkylation of a cortisol receptor. 相似文献
232.
P. Pani A. Sanna M. I. Brigaglia A. Columbano L. Congiu 《Cellular and molecular life sciences : CMLS》1976,32(11):1449-1451
Summary Acute toxicity induced by DMN was partially prevented by previously administering methyl mercuric chloride (MMC), a chemical inhibitor of the drug metabolizing enzyme system (DMES). We have studied the early changes occurring during the course of DMN-intoxication, namely disaggregation of polysomal profiles and necrosis, evaluated morphologically and by the release of S-GPT.This work was supported by Consiglio Nazionale delle Ricerche, Roma, Italy. 相似文献
233.
Summary The serum activities of aspartate aminotransferase, alanine aminotransferase, -hydroxybutyrate dehydrogenase and creatine phosphokinase have been measured in the African elephant. In general, the values were broadly comparable with those of man except that alanine aminotransferase was much lower and creatine phosphokinase higher. No variation due to age, sex, season or location was observed. 相似文献
234.
Unique Golgi apparatus and vesicle formation in a red alga. 总被引:2,自引:0,他引:2
235.
We examined effects of several vasoactive peptides (substance P, physalaemin, neurotensin, bradykinin, angiotensin etc.) on the excitability of molluscan giant neurones identified in the subesophageal ganglia of Achatina fulica Férussac. Of these peptides, only physalaemin showed a remarkable excitatory effect on a giant tonically autoactive neurone. 相似文献
236.
R. Tirri Anneli Siltovuori M. Harri 《Cellular and molecular life sciences : CMLS》1976,32(10):1283-1285
Summary Daily injections of phenylephrine or isoprenaline for 4 or 7 days lowered the chronotropic sensitivity of -adrenoreceptors in isolated rat atria.This study was supported by grants from the National Science Council of Finland. 相似文献
237.
V. R. Osório E Castro M. G. P. Vale A. P. Carvalho 《Cellular and molecular life sciences : CMLS》1976,32(4):424-426
Summary The effect of the antibiotic X-537A on the phosphorylated ATPase (EP) was investigated. The results show that X-537A depresses the level of EP which is dependent on the Ca2+ gradient, while the Ca2+-independent EP is not affected.
Acknowledgments. This work was supported by grants from the Instituto de Alta Cultura of the Portuguese Ministry of Education (No. CB/2) and the Calouste Gulbenkian Foundation. 相似文献
238.
W. Rittel R. Maier M. Brugger B. Kamber B. Riniker P. Sieber 《Cellular and molecular life sciences : CMLS》1976,32(2):246-248
Summary Assays of 8 synthetic analogues of human calcitonin in rats showed that their hypocalcaemic activity was drastically reduced by deletion of the C-terminal amide group, chain-shortening or opening of the disulphide ring, but unaffected or enhanced by modification of the N-terminal amino group.
II. vgl.R. Maier, B. Kamber, B. Riniker andW. Rittel, Hormon. Metab. Res.7, 511 (1975).
Die hier verwendete, abgekürzte Schreibweise für Peptide folgt den Empfehlungen der IUPAC-IUB Kommission für Biochemische Nomenklatur, J.B.C.247, 977 (1972). Weitere Abkürzungen: HCT, Human-Calcitonin; PCT, Schweinecalcitonin; Bmp, -Mercaptopropionsäure (Desaminocystein); NMet, Normethionin (S-Methylcystein); -OMe, Methylester. 相似文献
II. vgl.R. Maier, B. Kamber, B. Riniker andW. Rittel, Hormon. Metab. Res.7, 511 (1975).
Die hier verwendete, abgekürzte Schreibweise für Peptide folgt den Empfehlungen der IUPAC-IUB Kommission für Biochemische Nomenklatur, J.B.C.247, 977 (1972). Weitere Abkürzungen: HCT, Human-Calcitonin; PCT, Schweinecalcitonin; Bmp, -Mercaptopropionsäure (Desaminocystein); NMet, Normethionin (S-Methylcystein); -OMe, Methylester. 相似文献
239.
R. G. G. Andersson H. J. Arnqvist L. Lundholm 《Cellular and molecular life sciences : CMLS》1976,32(5):601-602
Summary The incorporation of leucice-14C into protein in bovine mesenteric arteries was augmented by cyclic GMP (10–3
M) and decreased by cyclic AMP (10–3
M). There was no effect of 5 AMP (10–3
M). The phosphodiesterase inhibiting drugs theophylline (10–3
M) and papaverine (5×10–5 g/ml) both decreased the leucine-14C incorporation.We are indebted to Mrs.Lena Burlin for hear assistance. Finacial support has been provided by the Swedish State Medical Research Council (No. 04X-101X-4498). 相似文献
240.
H. N. Nigg J. A. Svoboda M. J. Thompson S. R. Dutky J. N. Kaplanis W. E. Robbins 《Cellular and molecular life sciences : CMLS》1976,32(4):438-439
Summary An ecdysone 20-hydroxylase enzyme system that converts -ecdysone to 20-hydroxyecdysone was prepared from the midgut of the tobacco hornworm prepupa. This partially purified enzyme is NADPH dependent and is localized in the mitochondrial fraction of the midgut tissue. 相似文献