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131.
李红信 《西南民族学院学报(自然科学版)》2004,30(3):362-364
实现一个由ZR36060完成图像编解码,CS8900芯片实现TCP/IP协议,完成数据传榆,单片机则完成数据的调度、管理,对各部件的初始化和控制,完全不依赖复杂的实时操作系统,仅依靠单片机自身的监控系统和部分自主开发的应用软件,即可实现一个瘦客户型的局域安保监视系统。 相似文献
132.
就世界文化课程内容的具体设置,及联合大学与传媒以更好地实现课程积极目标等诸问题进行探讨.通过多层次的论证强调指出人们始终持有相异或相冲突的宗教、哲学以及意识形态,尚没有一种普世真理足以使世间所有人心悦诚服.即便是广泛接受和运用中的科学知识,其发展亦受阻于人类本身的局限而不可确定.尽管科学在前沿问题研究上竞争激烈,也仍然无法回答和消除所有的问题和差异.因此,从全球或泛人类立场观之,人类现有的知识与理解能力具有不确定和不完整的特点,而这样的特点浸透在所有的具体文化信仰之中.认识到共同局限性的人们--尤其是政界的领导人--亟需摒弃极端的文化分离思想,以更宽容理解的心态思考和行动,这样才能避免不同民族及不同国家间的不断冲突和互相伤害. 相似文献
133.
Localization of a Robotic Capsule for GI Motility Inspection with a Portable Ultrasonic System 总被引:5,自引:0,他引:5
IntroductionResearchesonmicromedicaldeviceandmicromedicalrobot,especiallytheinvivoinspectionsystemworkinginalimentarycanalorinbloodvesselwithlittledamageornondamagetohumanbodyhavebeenundertakenandreportedbyexpertsinmanycountries.Thesesystemsusuallyownmanyadvantagessuchas:smallvolume,lowpowerconsumption,littleinterferencetoworkingsurroundings,socangreatlyenlargethescopesofmedicalexaminationandrelievethepatientsofdiscomfortcausedbynormalprocedures.Thecapsuleendoscope“NORIKAsystem”developedby… 相似文献
134.
135.
Minimum information about a microarray experiment (MIAME)-toward standards for microarray data. 总被引:36,自引:0,他引:36
A Brazma P Hingamp J Quackenbush G Sherlock P Spellman C Stoeckert J Aach W Ansorge C A Ball H C Causton T Gaasterland P Glenisson F C Holstege I F Kim V Markowitz J C Matese H Parkinson A Robinson U Sarkans S Schulze-Kremer J Stewart R Taylor J Vilo M Vingron 《Nature genetics》2001,29(4):365-371
Microarray analysis has become a widely used tool for the generation of gene expression data on a genomic scale. Although many significant results have been derived from microarray studies, one limitation has been the lack of standards for presenting and exchanging such data. Here we present a proposal, the Minimum Information About a Microarray Experiment (MIAME), that describes the minimum information required to ensure that microarray data can be easily interpreted and that results derived from its analysis can be independently verified. The ultimate goal of this work is to establish a standard for recording and reporting microarray-based gene expression data, which will in turn facilitate the establishment of databases and public repositories and enable the development of data analysis tools. With respect to MIAME, we concentrate on defining the content and structure of the necessary information rather than the technical format for capturing it. 相似文献
136.
Nuclear transfer into mouse zygotes 总被引:6,自引:0,他引:6
137.
138.
Purification and cloning of amyloid precursor protein beta-secretase from human brain 总被引:40,自引:0,他引:40
Sinha S Anderson JP Barbour R Basi GS Caccavello R Davis D Doan M Dovey HF Frigon N Hong J Jacobson-Croak K Jewett N Keim P Knops J Lieberburg I Power M Tan H Tatsuno G Tung J Schenk D Seubert P Suomensaari SM Wang S Walker D Zhao J McConlogue L John V 《Nature》1999,402(6761):537-540
Proteolytic processing of the amyloid precursor protein (APP) generates amyloid beta (Abeta) peptide, which is thought to be causal for the pathology and subsequent cognitive decline in Alzheimer's disease. Cleavage by beta-secretase at the amino terminus of the Abeta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated carboxy-terminal fragment. Cleavage of the C-terminal fragment by gamma-secretase(s) leads to the formation of Abeta. The pathogenic mutation K670M671-->N670L671 at the beta-secretase cleavage site in APP, which was discovered in a Swedish family with familial Alzheimer's disease, leads to increased beta-secretase cleavage of the mutant substrate. Here we describe a membrane-bound enzyme activity that cleaves full-length APP at the beta-secretase cleavage site, and find it to be the predominant beta-cleavage activity in human brain. We have purified this enzyme activity to homogeneity from human brain using a new substrate analogue inhibitor of the enzyme activity, and show that the purified enzyme has all the properties predicted for beta-secretase. Cloning and expression of the enzyme reveals that human brain beta-secretase is a new membrane-bound aspartic proteinase. 相似文献
139.
A novel metalloproteinase gene specifically expressed in stromal cells of breast carcinomas. 总被引:46,自引:0,他引:46
P Basset J P Bellocq C Wolf I Stoll P Hutin J M Limacher O L Podhajcer M P Chenard M C Rio P Chambon 《Nature》1990,348(6303):699-704
A gene has been identified that is expressed specifically in stromal cells surrounding invasive breast carcinomas. On the basis of its sequence, the product of this gene, named stromelysin-3, is a new member of the family of metalloproteinase enzymes which degrade the extracellular matrix. The suggestion is that stromelysin-3 is one of the stroma-derived factors that have long been postulated to play an important part in progression of epithelial malignancies. 相似文献
140.