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991.
A. Velázquez H. Andreu N. Xamena A. Creus R. Marcos 《Cellular and molecular life sciences : CMLS》1987,43(10):1122-1123
Summary Viability tests were performed on second and third chromosomes from lines ofDrosophila melanogaster selected for increased resistance to the organophosphorus insecticides dichlorvos and malathion, in order to evaluate the accumulation of drastic alleles. Our results show that malathion reduces significantly the relative viability of chromosome 3 and also increases the frequency of drastic alleles in this chromosome, while dichlorvos increases significnatly the frequency of drastic alleles in chromosome 2.Work supported in part by the Spanish Ministry of Education and Science (Grant No. 0577/84 CAICYT).—We are grateful to Productos Cruz Verde S.A. and Agrocrós S.A. for generously supplying the insecticides dichlorvos and malathion, respectively. 相似文献
992.
Summary Large nuclear blebs have been observed in oocytes of the fish,Clarias batrachus. The bleb, which contains nucleoplasm, is finally extruded from the nucleus. The extruded body is DNase-sensitive, and it implies that some amount of DNA is extruded from the nucleus of these oocytes.Acknowledgments. We are thankful to Dr. R.K. Sharan, Department of Zoology, Patna University, for providing laboratory facilities, and to Dr V.G. Jhingran and Dr P.V. Dehadrai of ICAR for their keen interest in the work. 相似文献
993.
994.
N Ogata 《Experientia》1979,35(9):1202-1203
Electrical activities of the hypothalamic and interpeduncular neurons were studied in vitro in brain slices prepared from the guinea-pig brain stem. Neurons preserved resting membrane potentials comparable to those of neurons in vivo, responded to stimulation of the afferent fibres, and retained stable spontaneous firings for more than several hours. 相似文献
995.
Zh. A. Medvedev M. N. Medvedeva H. M. Crowne 《Cellular and molecular life sciences : CMLS》1984,40(11):1282-1284
Summary Electrophoretic analysis of histones and non-histone acid-soluble proteins in active (nuclease sensitive) and inactive chromatin from liver of young and old CBA mice and in age-related hepatocarcinomas showed a higher ratio of NHP: histones in active chromatin in old cells. Some liver- and hepatoma-specific fractions of non-histone proteins have been identified as chromatin matrix proteins. 相似文献
996.
997.
N. Kondo 《Cellular and molecular life sciences : CMLS》1987,43(8):873-875
Summary During the hibermating season, the amplitude of the cardiac action potential plateau of nonhibernating chipmunks was reduced. Replacing external Ca by Sr inhibited the electromechanical responses of these preparations. Similar properties were observed in hibernating animal preparations, suggesting that changes in cardiac function are already triggered before hibernation begins.15 December 1986 相似文献
998.
Interferon enhances 2-5A synthetase in embryonal carcinoma cells 总被引:13,自引:0,他引:13
Mouse teratocarcinomas provide a useful model of mammalian differentiation, because the malignant embryonal carcinoma (EC) stem cells of such tumours may produce various differential cell types in vivo or in vitro. Many EC cell lines have now been established and classified on the basis of their ability to differentiate in vivo into cell types characteristically derived from any of the three germ layers. There is convincing evidence that EC cells can neither produce interferon, nor respond to it by becoming resistant to virus, whereas differentiated cells derived from EC lines behave normally in both respects. We investigated the lack of responsiveness of EC cells towards interferon by measuring the levels of two double-stranded RNA-dependent enzyme activities recently shown to be enhanced by interferon. We report here that on treatment with interferon, EC cells show increased 2-5A synthetase levels comparable to those found in differentiated cells, while there is little or no effect on kinase activity in EC cells, in contrast to their differentiated counterparts. 相似文献
999.
1000.
A. Dobozy L. Kemény M. Csató J. Hunyadi A. Sz. Kenderessy N. Simon 《Cellular and molecular life sciences : CMLS》1984,40(12):1403-1404
Summary An enhancement effect of mouse erythrocyte rosette forming (MERF) cells on the production of migration inhibitory factor, chemotactic factor for neutrophils and skin reactive factor in T-lymphocyte cultures stimulated with the purified protein derivative of tuberculin was observed. We consider it likely that the MERF cells, possessing the appropriate cell surface constituents to construct an immunogenic moiety, present antigen on their surfaces to elicit lymphokine production.This work was supported by the Scientific Research Council, Ministry of Health, Hungary, Code No. 421030401 1/s 相似文献