Removal of polyethylene glycols from immunoglobulin samples by adsorption chromatography on polystyrene beads

Summary A chromatographic method is described for 80% removal of polyethylene glycol of different types, 600–6000, from human immunoglobulin preparations. Bio-beads SM-2 were used in batch procedures or packed on a 16×100 mm column. The polyethylene glycols were desorbed with 75% ethanol.     

Dialyzable serum factors alter cellular immunity in pregnancy

Summary Lymphocyte responsiveness was found to be decreased in pregnant and increased in habitually aborting women. This is attributed to a dialyzable serum factor(s), that can be removed from the surface of lymphocytes by repeated washing.     

Threo-3,4-Dihydroxyphenylserine,a poor source of noradrenaline in the rat

Résumé Chez le rat, les injections dedl-thréo-3,4-dihydroxyphénylsérine, un précurseur pharmacologique synthétique de la noradrénaline, provoquent une conversion de moins de 1% au 4-hydroxy-3-méthoxyphényl-glycol, le métabolite urinaire majeur de la noradrénaline dans cette espèce. Un nouveau cheminement qui entraîne une coupure latérale de la chaîne prit environ 10% de la dose et un autre 10% fût excrété comme un amino-acideO-méthylé; le sort de quelque 80% est inconnu.     

Central effect of 5,8,11,14-eicosatetraenoic acid (arachidonic acid) on the temperature in the conscious rabbit

Hyperthermia induced by arachidonic acid in rabbit was attenuated by phenoxybenzamine, cyproheptadine and indomethacin. The reduction in arachidonic acid hyperthermia, after 6-OH-DA and the failure of PCPA to reduce this rise, indicates the involvement of noradrenaline in arachidonic acid hyperthermia.     

Quaternary alkaloid of the bark ofAlstonia venenata R. Br.

Zusammenfassung Ein aus der Rinde vonAlstonia venenata isoliertes quartäres Alkaloid wurde als 3-Dehydroalstovenin identifiziert.