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791.
介绍了一种新的基于缓冲区管理的网络拥塞控制方法,该控制方法通过监测网络状态变化和客户端缓冲区状态,动态调整服务器端的发送速率,能够有效提高服务质量.结果表明该方法在流媒体网络传输中能够取得很好的效果. 相似文献
792.
研究了基波磁势自平衡串并联混合有源电力滤波器.其串联在系统和谐波负载之间的零磁通变流器可自动实现对基波呈现低阻抗,对谐波呈现高阻抗,并可实时方便地检测出剩余谐波电流流过变流器时产生的谐波电压降.通过逆变器产生一个与检测到的谐波电压成正比的谐波电压源,并通过耦合变压器与无源滤波器串联之后再并联接入电网,从而更好地减少流入系统的谐波电流.实验结果证明了结论的正确性. 相似文献
793.
文章回顾了人类探索空间的历史,特别是中国人对空间的探索历史;并分析了自人类进入空间时代以后探索空间的历程。通过对这一系列活动的分析,探讨了人类在空间探测活动中的动机及其科学内涵,进而对中国今后空间探测活动的战略科学目标展开讨论,并简要介绍了中国4个空间探测计划及其科学目标。 相似文献
794.
研究了TH65100卧式加工中心立柱的结构设计和分析系统。利用Pro/Engineer和Ansys软件分别作为设计系统和分析系统,利用数据交换接口,对立柱进行三维实体建模与模态分析。得到了立柱的模态分析结果,并对比了2种筋板优化方法。取得了既减轻机身重量,又提高强度和刚度的显著效果,为结构的合理设计与改造提供了可靠的理论依据。 相似文献
795.
在分析岩体边坡稳定性的基础上,建立受非均布线形荷载作用的地基力学模型,应用叠加原理推导出岩体表面在上述荷载作用下,预应力锚索-地梁结构中垂直于梁轴线的平面内的地基中深z处的应力和位移计算公式,为研究预应力锚索-地梁结构在岩体中传递规律提供了理论基础.并以湖南省常张高速公路K123+160-K123+369边坡为实验区域,现场实验得出在对锚索施加预应力后,锚索预应力通过地梁传递给被加固的岩土体,其传递方式在垂直于地梁轴线的平面内是以梁轴线与该平面的交点为端点的近似橢圆的等值面形式由内向外呈逐渐衰减趋势分布的.藉此证明预应力锚索-地梁结构在山区高速公路岩体边坡中是一种可靠的处理技术. 相似文献
796.
Stress changes from the 2008 Wenchuan earthquake and increased hazard in the Sichuan basin 总被引:39,自引:0,他引:39
On 12 May 2008, the devastating magnitude 7.9 (Wenchuan) earthquake struck the eastern edge of the Tibetan plateau, collapsing buildings and killing thousands in major cities aligned along the western Sichuan basin in China. After such a large-magnitude earthquake, rearrangement of stresses in the crust commonly leads to subsequent damaging earthquakes. The mainshock of the 12 May earthquake ruptured with as much as 9 m of slip along the boundary between the Longmen Shan and Sichuan basin, and demonstrated the complex strike-slip and thrust motion that characterizes the region. The Sichuan basin and surroundings are also crossed by other active strike-slip and thrust faults. Here we present calculations of the coseismic stress changes that resulted from the 12 May event using models of those faults, and show that many indicate significant stress increases. Rapid mapping of such stress changes can help to locate fault sections with relatively higher odds of producing large aftershocks. 相似文献
797.
Warne T Serrano-Vega MJ Baker JG Moukhametzianov R Edwards PC Henderson R Leslie AG Tate CG Schertler GF 《Nature》2008,454(7203):486-491
G-protein-coupled receptors have a major role in transmembrane signalling in most eukaryotes and many are important drug targets. Here we report the 2.7 A resolution crystal structure of a beta(1)-adrenergic receptor in complex with the high-affinity antagonist cyanopindolol. The modified turkey (Meleagris gallopavo) receptor was selected to be in its antagonist conformation and its thermostability improved by earlier limited mutagenesis. The ligand-binding pocket comprises 15 side chains from amino acid residues in 4 transmembrane alpha-helices and extracellular loop 2. This loop defines the entrance of the ligand-binding pocket and is stabilized by two disulphide bonds and a sodium ion. Binding of cyanopindolol to the beta(1)-adrenergic receptor and binding of carazolol to the beta(2)-adrenergic receptor involve similar interactions. A short well-defined helix in cytoplasmic loop 2, not observed in either rhodopsin or the beta(2)-adrenergic receptor, directly interacts by means of a tyrosine with the highly conserved DRY motif at the end of helix 3 that is essential for receptor activation. 相似文献
798.
Superconductivity at 43 K in SmFeAsO1-xFx 总被引:2,自引:0,他引:2
Since the discovery of high-transition-temperature (high-T(c)) superconductivity in layered copper oxides, extensive effort has been devoted to exploring the origins of this phenomenon. A T(c) higher than 40 K (about the theoretical maximum predicted from Bardeen-Cooper-Schrieffer theory), however, has been obtained only in the copper oxide superconductors. The highest reported value for non-copper-oxide bulk superconductivity is T(c) = 39 K in MgB(2) (ref. 2). The layered rare-earth metal oxypnictides LnOFeAs (where Ln is La-Nd, Sm and Gd) are now attracting attention following the discovery of superconductivity at 26 K in the iron-based LaO(1-x)F(x)FeAs (ref. 3). Here we report the discovery of bulk superconductivity in the related compound SmFeAsO(1-x)F(x), which has a ZrCuSiAs-type structure. Resistivity and magnetization measurements reveal a transition temperature as high as 43 K. This provides a new material base for studying the origin of high-temperature superconductivity. 相似文献
799.
800.
Understanding cellular response to environmental stress has broad implications for human disease. AMP-activated protein kinase (AMPK) orchestrates the regulation of energy-generating and -consuming pathways, and protects the heart against ischaemic injury and apoptosis. A role for circulating hormones such as adiponectin and leptin in the activation of AMPK has received recent attention. Whether local autocrine and paracrine factors within target organs such as the heart modulate AMPK is unknown. Here we show that macrophage migration inhibitory factor (MIF), an upstream regulator of inflammation, is released in the ischaemic heart, where it stimulates AMPK activation through CD74, promotes glucose uptake and protects the heart during ischaemia-reperfusion injury. Germline deletion of the Mif gene impairs ischaemic AMPK signalling in the mouse heart. Human fibroblasts with a low-activity MIF promoter polymorphism have diminished MIF release and AMPK activation during hypoxia. Thus, MIF modulates the activation of the cardioprotective AMPK pathway during ischaemia, functionally linking inflammation and metabolism in the heart. We anticipate that genetic variation in MIF expression may impact on the response of the human heart to ischaemia by the AMPK pathway, and that diagnostic MIF genotyping might predict risk in patients with coronary artery disease. 相似文献