Relaxin family peptide systems and the central nervous system

Since its discovery in the 1920s, relaxin has enjoyed a reputation as a peptide hormone of pregnancy. However, relaxin and other relaxin family peptides are now associated with numerous non-reproductive physiologies and disease states. The new millennium bought with it the sequence of the human genome and subsequently new directions for relaxin research. In 2002, the ancestral relaxin gene RLN3 was identified from genome databases. The relaxin-3 peptide is highly expressed in a small region of the brain and in species from teleost to primates and has both conserved sequence and sites of expression. Combined with the discovery of the relaxin family peptide receptors, interest in the role of the relaxin family peptides in the central nervous system has been reignited. This review explores the relaxin family peptides that are expressed in or act upon the brain, the receptors that mediate their actions, and what is currently known of their functions.     

Influence of precipitation and temperature on ring, annual branch increment, and needle growth of White Fir and Douglas-fir in central Utah

The study evaluates growth variations in mixed stands of Douglas-fir ( Pseudotsuga menziesii (Mirb.) Franco) and White Fir ( Abies concolor Hoopes) from the Bighorn Ranch in northern Sanpete County, Utah. The study area lies 26 km southwest of Thistle, Utah. Tree-ring width, annual branch growth and needle length for the period 1970–1976 were obtained from Douglas-Fir and White Fir individuals distributed along an altitudinal and moisture gradient. Elevation ranged from 2257 m to 2500 m above sea level. Temperature and precipitation are shown to exert a significant influence on needle and annual branch growth and width of the annual rings. It was found that multiple correlation coefficients were always larger than the simple correlation coefficients. This suggests that the trees are responding to both temperature and precipitation. Annual branch growth is shown to be positively correlated with ring width and needle length. The influence of precipitation on growth is synchronized with 1 October–1 June precipitation. Best growth occurs in cool, moist years and at lower elevations.     

Stem cells find their niche.

The concept that stem cells are controlled by particular microenvironments known as 'niches' has been widely invoked. But niches have remained largely a theoretical construct because of the difficulty of identifying and manipulating individual stem cells and their surroundings. Technical advances now make it possible to characterize small zones that maintain and control stem cell activity in several organs, including gonads, skin and gut. These studies are beginning to unify our understanding of stem cell regulation at the cellular and molecular levels, and promise to advance efforts to use stem cells therapeutically.     

Catastrophic wildfire and number of populations as factors influencing risk of extinction for Gila trout ( Oncorhynchus gilae )

We used the computer program RAMAS to explore the sensitivity of an extinction-risk model for the Gila trout ( Oncorhynchus gilae ) to management of wildfires and number of populations of the species. The Gila trout is an endangered salmonid presently restricted to very few headwaters of the Gila and San Francisco river tributaries in southwestern New Mexico. Life history data for 10 extant populations were used to examine sensitivity of the species viability to changes in a variety of factors including population size, fecundity, life stage structure, number of populations, severity and probability of forest fires, and a regulated fishery. The probability and severity of forest fires and number of populations had the greatest effect on viability. Results indicate that successful conservation of Gila trout requires establishment of additional populations and reduction of the severity of forest fires through a program incorporating more frequent, but less severe, fires.     

Richard Watson

The development of the circular dividing engine in England is traced from Henry Hindley and Jesse Ramsden through the improvements introduced by Ramsden's successors to the self-acting engine of William Simms. Particular emphasis is given to the invention, evolution and transmission of the methods used to achieve accuracy in: dividing the wheel; ratching the teeth and matching them to the endless screw; and mounting the cutter. The procedures adopted by Ramsden and Troughton for correcting initial dividing marks are also described.     

Temporal and spatial patterns of small mammal density and species composition on a radioactive waste disposal area: the role of edge habitat

Small mammal populations inhabiting radioactive waste disposal areas could be important vectors of contaminant redistribution, given sufficiently high numbers. Earlier studies conducted at the Subsurface Disposal Area (SDA) in southeastern Idaho found small mammal densities equaling or exceeding densities in native habitat. Our live-trapping study was conducted in 1988 and 1989 to assess the role of edge habitat (where SDA crested wheatgrass [ Agropyron cristatum ] plantings and native sagebrush habitat are separated by an earthen dike) in facilitating use of this highly modified site by small mammals. Small mammals had a significantly greater density in SDA edge habitat than in the interior. Total density of small mammals and immediately around the SDA appeared to be less variable over time than density in native sagebrush habitat for years when data were available. This phenomenon was largely attributable to steady or increasing SDA population densities of the most common species, Peromyscus maniculatus and Perognathus parvus , during 1988-89, when most small mammal species had below-average densities in surrounding areas. The variety of foraging options in edge habitat may have allowed these relatively opportunistic species to avoid widespread population declines associated with drought years in 1988-89. Movements by P. manicualtus across the boundary were common, suggesting that this species did indeed utilize both habitat types. Preferences for edge habitat could potentially be used to formulate strategies that reduce use of waste site by small mammals.     

Size selection of food by cutthroat trout, Salmo clarki, in an Idaho stream

The mean size of food and amount of food consumed by cutthroat trout from Palisades Creek in southeastern Idaho increased with trout length. Number of organisms of terrestrial origin, number of aquatic larvae, number of ants, and number of berries from redstem dogwood were related to trout length. The size range and number of taxa consumed increased with trout size, indicating that as trout get larger, they broaden their feeding menu. The minimum size of food consumed was relatively constant for all trout, but larger trout appeared to feed more from the stream bottom. Trout may have a minimum length of food, below which items cannot be detected as food. Other possible factors affecting the feeding of cutthroat trout are mentioned.         

Nesting and summer habitat use by translocated Sage Grouse ( Centrocercus Urophasianus ) in central Idaho

We translocated 196 Sage Grouse ( Centrocercus urophasianus into Sawtooth Valley, Idaho, during March-April 1986-87 to augment a small resident population. Forty-four grouse equipped with radio transmitters were monitored through spring and summer. Nest sites ( n = 6) had greater ( P = .032) horizontal cover than did independent random plots ( n = 7). During summer, grouse used sites ( n = 50) with taller live and dead shrub heights, greater shrub canopy cover, and more ground litter ( P n = 50) 50-300 m from use sites. Distance to edge and mountain sagebrush ( Artemisia tridentata vaseyana ) density best separated use sites from independent random plots in logistic regression analysis and correctly classified 64% of the use sites and 78% of the independent random plots. Sage Grouse used sties that had narrower frequency distributions for many variables than did independent plots ( P < .04), suggesting selection for uniform habitat.     

Variation in Lewsia kelloggii (Portulacaceae) with description of a new species endemic to Idaho

Lewisia kelloggii has been understood as a rare plant with a disjunct range in California and Idaho. Examination of herbarium specimens and analysis of isozymes in 6 Idaho and 7 California populations revealed consistent differences between plants of the 2 states. Fixed differences in alleles at 2 loci (AAT2 and PGI1) distinguished Idaho from California plants. Genetic identities based on isozymes between Idaho and California populations averaged 0.58, lower than the average for congeneric plant species. Idaho plants were smaller than most California plants, but California plants were variable. The most consistent morphological difference between Idaho and California specimens was the difference in the number of glands on the margins of bracts and sepals. Idaho plants had 0 (-5) pink glands on each margin of these organs, all on teeth near the tips. In California plants these organs had 12-25 glands on each margin, the distal ones elevated on teeth and the proximal ones sessile. We recognize the Idaho plants as a new species, L. sacajaweana , and retain the name L. kelloggii for the California populations.