Neuroglobin mutation associated with hypoxia adaptation in Tibet chicken

Globin protein family plays an important role in storing and transporting oxygen. As a newly reported globin, the revealed function of neuroglobin includes binding and storing oxygen as well as facilitating the utilization of oxygen in neuronal cells. In the present study, mutations in exons of chicken Ngb gene were identified with the method of sequencing and created restriction site PCR in Tibet chicken and other four lowland chicken breeds. The mutations of Lys-2224(E4)-Asn and Ser-2279(E4)-Gly were identified in exon 4 of the gene. The Lys-2224(E4)-Asn mutation existed only in Tibet chicken and the mutation frequencies increased with increasing altitude. Analysis of the haplotype and diplotype of the two mutations in Tibet chicken populations of different altitudes showed that the frequencies of TG haplotype and TTGG diplotype also increased with increasing altitude, while the reverse tendency was found on GGAA diplotype. Under the hypoxic simulation incubation, the main haplotype was TG in living embryos and GA in dead embryos. The results showed that the Lys-2224(E4)-Asn mutation may be a specific mutation associated with hypoxia adaptation in Tibet chicken.     

Neuroglobin mutation associated with hypoxia adaptation in Tibet chicken

Globin protein family plays an important role in storing and transporting oxygen. As a newly reported globin, the revealed function of neuroglobin includes binding and storing oxygen as well as facilitating the utilization of oxygen in neuronal cells. In the present study, mutations in exons of chicken Ngb gene were identified with the method of sequencing and created restriction site PCR in Tibet chicken and other four lowland chicken breeds. The mutations of Lys-2224(E4)-Asn and Ser-2279(E4)-Gly were identified in exon 4 of the gene. The Lys-2224(E4)-Asn mutation existed only in Tibet chicken and the mutation frequencies increased with increasing altitude. Analysis of the haplotype and diplotype of the two mutations in Tibet chicken populations of different altitudes showed that the frequencies of TG haplotype and TTGG diplotype also increased with increasing altitude, while the reverse tendency was found on GGAA diplotype. Under the hypoxic simulation incubation, the main haplotype was TG in living embryos and GA in dead embryos. The results showed that the Lys-2224(E4)-Asn mutation may be a specific mutation associated with hypoxia adaptation in Tibet chicken.     

Knowledge discovery from communication network alarm databases

The technique of Knowlege Discovery in Databases (KDD) to learn valuable knowledge hidden in network alarm databases is introduced. To get such knowledge, we propose an efficient method based on sliding windows (named as Slidwin) to discover different episode rules from time squential alarm data. The experimental results show that given different thresholds parameters, large amount of different rules could be discovered quickly. Foundation item: Supported by the National 863 High-Tech Project (863-306-Z705-02) and National Natural Science Foundation of China (69896240) Biography: Wang Xi-miao (1973-), female, Ph. D. candidate. Research interests: network management and information processing.     

关于Huxley方程高阶奇点的定性分析

Huxley方程在y轴两个方向上的无穷远点为不定号情况下的高阶奇点,利用水平等倾线与垂直等倾线构成的曲边扇形域来研究该类奇点轨线的定性结构,得到了y轴两个方向上的无穷远点有无数条积分曲线进入或走出的结论。     

y+值对翼型气动参数计算精度的影响研究

基于RAE 2822翼型,为了研究粘性底层无量纲参数y+对翼型气动参数计算精度的影响,采用ANSYS ICEM剖分的计算域网格和三维N-S控制方程的有限体积法离散格式,选取SST湍流模型,在不同的y+值下借助ANSYS CFX模块数值计算了该翼型的气动参数,分析了相对误差,绘制了压力系数分布云图。结果表明:过大的y+值导致误差增大;在y+的理论值11.63附近,计算精度变化较小;较小的y+可使精度进一步提高,但过小的y+并不能得到过高的计算精度。y+值对翼型边界不同区域的计算精度影响有所不同,翼型气动参数数值计算时推荐y+取2-4。     

C语言课程教学方法改革探讨

运用现代教育思想和教学理论,从选择教学内容、强化实践教学、改革评价体系、改进教学方法、更新教学手段、加强师资队伍建设等方面阐述提高C语言程序设计的教学效果和教学质量的重要性.同时提出创新性教学方法和多样化的教学手段,特别是要充分利用校园网是C语言课程教学的必然要求.     

迈克尔逊干涉仪非对称补偿的分析及校准

本文主要对迈克尔逊干涉仪处于非对称补偿状态进行了分析，定量得出补偿镜偏离量与光程差之间的关系，并就如何判断偏离和校准偏离提出了一种方法。     

高校非计算机专业计算机基础教育研究与实践

本文对高校非计算机专业的计算机基础教育的背景与现状、培养目标与基本任务进行了研究 .提出若干改革措施 ,并进一步论述了层次教育问题 .     

煤炭运销信息化管理问题与对策研究

分析了我国煤炭企业实现信息化过程中存在的问题，指出其中软件公司存在的问题，并对煤炭运销信息化进行了系统分析，构建了煤炭运销信息化的框架，提出了要因地制宜地搞好信息化建设；建立完备的项目管理体制和运作体制；企业信息化需要不断的发现需求，升级软硬件，满足用户不断提高的要求。     

FCC催化剂钒污染及捕钒剂的研究

对一种工业ＦＣＣ催化剂进行处理后，制得载钒量在ｗｖ＝０．００１－０．０１之间的一组样品，并在７５０℃和１００％水蒸汽条件下逐个流化４ｈ，然后进行ＦＴＩＲ酸性表征和ＸＲＤ分析。实验结果表明Ｂ酸和Ｌ酸均随载钒量的增加而减少，在酸性位数目减少的过程中，酸的强弱比例基本不变；ＸＲＤ结果表明，随着载钒量的增加，样品的衍射峰强度几乎呈线性下降，在ｗｖ＝０．００５的载钒量条件下进行不同捕钒剂量的研究，发现捕钒剂