自愈式低压电力电容器安全监测系统设计

针对自愈式低压电力电容器运行过程中受到电网环境温度和使用状况等影响,从而失去自愈功能,引发电网故障的问题,设计安全监测系统以保障其安全运行.在分析自愈式低压电力电容器工作特点的基础上,提出安全监测系统的设计方案;阐述各功能模块的工作原理及过程,指出该系统的应用优势;给出工程应用的具体安装实施方案.实验结果表明,该系统能...     

Ba0.65Sr0.35TiO3薄膜的磁控溅射法制备与介电性能研究

用磁控溅射法在Pt/Ti/SiO2/Si衬底上沉积Ba0.65Sr0.35TiO3薄膜.研究沉积气压和衬底温度对BST薄膜结构及介电性能的影响.应用XRD和AFM表征薄膜的物相结构及其表面形貌,通过阻抗分析仪测量薄膜的介电性能.结果表明在3.0 Pa沉积气压和600℃衬底温度下制备的Ba0.65Sr0.35TiO3薄膜有较好的微结构和介电性能.     

细水煤矿"3.19"瓦斯爆炸事故救灾与分析

本文介绍了细水煤矿"3.19"瓦斯爆炸事故的抢救经过,分析了事故发生的原因,对事故抢救过程中关键环节决策的科学性进行了分析,最后经过科学决策和科学救援,在极短的时间内完成了救援任务,对今后处理类似矿井事故实施救灾指挥,有一定的借鉴作用.     

基坑工程中悬臂桩支护结构设计

应用朗肯土压力理论及力学平衡原理对桩支护结构(嵌固深度、桩长、最大弯矩值及其位置)进行设计,同时对受侧压较大的圆截面桩进行配筋计算,并采用远离中和轴的不均匀布置方式极大地节约了钢筋的用量.     

d-界距离正则图中一类格的特征多项式

设Г是一个直径d≥3的d-界距离正则图,x∈V(Г),P(x)是Г中包含x的所有强闭包子图的集合,并且P(x,i)是P(x)中所有直径为i的强闭包子图的集合.设￡(x,i)是P(x,i)中元素的交生成的集合.按反包含关系规定￡(x,i)的偏序,￡(x,i)记为￡R(x,i).利用M(o)bius反演公式计算了￡R((x,i)上的特征多项式X(PR(x),t).     

Fe含量对FePt磁性薄膜的微结构和磁特性的影响

用直流磁控溅射方法和原位退火工艺在玻璃基片上制备了FexPt100-x纳米颗粒膜.研究发现,Fe含量对FePt纳米颗粒膜的微结构和磁特性有很大的影响.矫顽力随Fe含量的增加而增大,当x=48时矫顽力Hc达到了1 040 kA/m,样品出现很好的有序化L10结构扫描探针显微镜(SPM)观察结果显示,所有样品具有横跨数个晶粒的粒状磁畴,Fe48Pt52的粗糙度Ra大约0.6 nm.     

基于收缩视角的吉林省城镇化要素协调性测度

侧重于城市收缩的视角,综合引用标准差椭圆、协调耦合度、灰色关联系数等计量模型,借助ArcGIS和SPSS分析软件,对吉林省人口、用地、经济城镇化演进特征与协调性特征进行了分析研究.结果表明:(1)近10年来吉林省城镇人口、建设用地、城市经济指标均呈现出收缩的端倪,并且城镇化要素成长的空间差异性显著;(2)中部城市群是各...     

Analysis of the human protein interactome and comparison with yeast, worm and fly interaction datasets

We present the first analysis of the human proteome with regard to interactions between proteins. We also compare the human interactome with the available interaction datasets from yeast (Saccharomyces cerevisiae), worm (Caenorhabditis elegans) and fly (Drosophila melanogaster). Of >70,000 binary interactions, only 42 were common to human, worm and fly, and only 16 were common to all four datasets. An additional 36 interactions were common to fly and worm but were not observed in humans, although a coimmunoprecipitation assay showed that 9 of the interactions do occur in humans. A re-examination of the connectivity of essential genes in yeast and humans indicated that the available data do not support the presumption that the number of interaction partners can accurately predict whether a gene is essential. Finally, we found that proteins encoded by genes mutated in inherited genetic disorders are likely to interact with proteins known to cause similar disorders, suggesting the existence of disease subnetworks. The human interaction map constructed from our analysis should facilitate an integrative systems biology approach to elucidating the cellular networks that contribute to health and disease states.     

Differentiated cells are more efficient than adult stem cells for cloning by somatic cell nuclear transfer

Since the creation of Dolly via somatic cell nuclear transfer (SCNT), more than a dozen species of mammals have been cloned using this technology. One hypothesis for the limited success of cloning via SCNT (1%-5%) is that the clones are likely to be derived from adult stem cells. Support for this hypothesis comes from the findings that the reproductive cloning efficiency for embryonic stem cells is five to ten times higher than that for somatic cells as donors and that cloned pups cannot be produced directly from cloned embryos derived from differentiated B and T cells or neuronal cells. The question remains as to whether SCNT-derived animal clones can be derived from truly differentiated somatic cells. We tested this hypothesis with mouse hematopoietic cells at different differentiation stages: hematopoietic stem cells, progenitor cells and granulocytes. We found that cloning efficiency increases over the differentiation hierarchy, and terminally differentiated postmitotic granulocytes yield cloned pups with the greatest cloning efficiency.     

De novo mutations in the gene encoding STXBP1 (MUNC18-1) cause early infantile epileptic encephalopathy

Early infantile epileptic encephalopathy with suppression-burst (EIEE), also known as Ohtahara syndrome, is one of the most severe and earliest forms of epilepsy. Using array-based comparative genomic hybridization, we found a de novo 2.0-Mb microdeletion at 9q33.3-q34.11 in a girl with EIEE. Mutation analysis of candidate genes mapped to the deletion revealed that four unrelated individuals with EIEE had heterozygous missense mutations in the gene encoding syntaxin binding protein 1 (STXBP1). STXBP1 (also known as MUNC18-1) is an evolutionally conserved neuronal Sec1/Munc-18 (SM) protein that is essential in synaptic vesicle release in several species. Circular dichroism melting experiments revealed that a mutant form of the protein was significantly thermolabile compared to wild type. Furthermore, binding of the mutant protein to syntaxin was impaired. These findings suggest that haploinsufficiency of STXBP1 causes EIEE.