On some significance tests in cluster analysis

We investigate the properties of several significance tests for distinguishing between the hypothesisH of a homogeneous population and an alternativeA involving clustering or heterogeneity, with emphasis on the case of multidimensional observationsx ₁, ...,x _n ^p . Four types of test statistics are considered: the (s-th) largest gap between observations, their mean distance (or similarity), the minimum within-cluster sum of squares resulting from a k-means algorithm, and the resulting maximum F statistic. The asymptotic distributions underH are given forn and the asymptotic power of the tests is derived for neighboring alternatives.     

A new semisynthetic ergot peptide alkaloid: DCN 203-922

Summary We report the synthesis, stereochemistry and preliminary pharmacological evaluation of DCN 203-922, a novel ergot alkaloid of the cyclol type, which contains in its peptide moiety the uncommon amino acid L-allo-isoleucine.Part of this paper was reported by this author at the Herbstversammlung der Schweizerischen Chemischen Gesellschaft, Bern, in October 1986.     

Hypothalamic histamine modulates adaptive behavior of rats at high environmental temperature

Summary Histamine content in the rat hypothalamus was lower at 4°C and higher at 31°C compared to that at 21°C. Pretreatment with -fluoromethylhistidine, a suicide inhibitor of histidine decarboxylase, attenuated both the increased level of hypothalamic histamine and rat adaptive behavior at 31°C. Increase of histamine content in the hypothalamus appears to be an important factor contributing to rat adaptive behavior to high environmental temperature.     

论运动量的安排

针对目前,大多数运动训练中,运动量安排上的不合理的状况,笔者在体操领域中进行了探索。通过对苏联、日本队夺得世界冠军前的训练的有关数据的统计,并结合自己的经验,进行了研究分析,在理论上提出了“训练的适应征象”。并得出了大运动量与成绩密切相关的结论。并且对训练的负荷密度、强度问题做了进一步阐述。     

Inhibition of the growth of cariogenic bacteria in vitro by plant falvanones

Phytoalexins, defensive compounds produced by plants against microbial infections, were purified fromSophora exigua (Leguminosae) and their growth inhibitory effects on oral cariogenic bacteria were determined in vitro. Among three isolated compounds, 5,7,2,4-tetrahydroxy-8-lavandulylflavanone completely inhibited the growth of oral bacteria including primary cariogenic mutans streptococci, other oral streptococci, actinomycetes, and lactobacilli, at concentrations of 1.56 to 6.25 g/ml.