Effect of Splice Marking on Fabric Roll Planning

Minimising the fabric loss during spreading can reduce the total production costs of garment manufacturing. Although marker planning is a major determinant of material utilisation, considerable savings on materials also will be made from the area of spreading loss. In the spreading process, it is general to have variance on the fabric yardage between each fabric roll, and the number of splice markings on each cutting lay is also varied. This paper aim to study how the fabric roll planning and the number of splice marks of a cutting lay will affect the material usage in the spreading process. By using a genetic algorithm approach, the amount of fabric to be saved by optimising the fabric roll sequence was derived by comparing the best arrangement and the worst arrangement of the fabric roll sequences of a cutting lay. The result of the study showed that both fabric roll planning and the number of splice marking have effect on the fabric loss. The findings could help the apparel manufacturer to reduce the     

面的并区域与三正则图的Ham ilton圈

Sachs. Kozyrev和 Grinbery指出了平面图具有 Hamilton圈的一个必要条件是 ∑ni=3 ( i-2 )i=∑ni=3 ( i-2 ) ′i=n-2 ,其中 i 和 ′i 分别为 Hamilton圈内 ,外度为 i的面数 ,在这个必要条件的基础上 ,给出了三正则平面图 Hamilton圈的一个算法     

TNF-induced necroptosis and PARP-1-mediated necrosis represent distinct routes to programmed necrotic cell death

Programmed necrosis is important in many (patho)physiological settings. For specific therapeutic intervention, however, a better knowledge is required whether necrosis occurs through one single “core program” or through several independent pathways. Previously, the poly(ADP-ribose) polymerase (PARP) pathway has been suggested as a crucial element of tumor necrosis factor (TNF)-mediated necroptosis. Here, we show that TNF-induced necroptosis and the PARP pathway represent distinct and independent routes to programmed necrosis. First, DNA-alkylating agents such as 1-methyl-3-nitro-1-nitrosoguanidine (MNNG) or methyl methanesulfonate rapidly activate the PARP pathway, whereas this is a late and secondary event in TNF-induced necroptosis. Second, inhibition of the PARP pathway does not protect against TNF-induced necroptosis, e.g., the PARP-1 inhibitor 3-AB prevented MNNG- but not TNF-induced adenosine-5′-triposphate depletion, translocation of apoptosis-inducing factor, and necrosis. Likewise, olaparib, a more potent and selective PARP-1 inhibitor failed to block TNF-induced necroptosis, identical to knockdown/knockout of PARP-1, pharmacologic and genetic interference with c-Jun N-terminal kinases and calpain/cathepsin proteases as further components of the PARP pathway. Third, interruption of TNF-induced necroptosis by interference with ceramide generation, RIP1 or RIP3 function or by the radical scavenger butylated hydroxyanisole did not prevent programmed necrosis through the PARP pathway. In summary, our results suggest that the currently established role of the PARP pathway in TNF-induced necroptosis needs to be revised, with consequences for the design of future therapeutic strategies.     

Which neurological abnormalities and neuropsychological impairments share the same substrate in psychosis?

Approximately 60% of subjects with schizophrenia present minor neurological signs (neurological soft signs, NSS), which include abnormalities in sensory and motor performance indicative of a non-specific cerebral dysfunction. These are also present in healthy individuals and relatives of patients with psychosis, at significantly lower rates. The excess of NSS in psychosis may be a potential endophenotype for this disorder, and reflect the same neurodevelopmental brain dysfunction that also underlies the cognitive deficits consistently reported in psychosis. To establish whether neurological and cognitive dysfunction meet the essential criterion required for a refined endophenotype for psychosis, the association with the illness, we explored evidence that certain neurological and cognitive deficits co-occur in affected individuals. This evidence suggests that signs of motor dysfunctions may be specific to patients with psychosis, in whom they are associated with dysfunction in cognitive tasks requiring motor skills. Thus, they may form a promising candidate endophenotype for psychosis.     

First episode psychosis with extrapyramidal signs prior to antipsychotic drug treatment

Extrapyramidal movement disorders are common in chronic schizophrenia, and may be an intrinsic feature of the illness as well as related to antipsychotic drug treatment. Similar dysfunctions at illness onset may have implications for outcome, and for under- standing the mechanisms of illness. The objectives were to examine the clinical correlates of pre-treatment movement disorders at first episode of psychosis, and determine associations with neuropsychological function and striatal structure. Never medicated subjects were recruited from consecutive admissions to Early Psychosis Programs with defined catchment areas in Hong Kong, China, and Halifax, Canada. Standardized clinical, neuropsychological and brain imaging assessments were carried out at baseline and following acute and long term treatment with typical or atypical antipsychotic drugs. At the Hong Kong site, we studied 84 subjects with first episode psychosis (n = 10 with EPS). At the Halifax site, we studied 40 subjects with first episode psychosis (n = 17 with EPS), and 23 healthy comparison subjects. Subjects with movement disorders prior to treatment (EPS+) had higher total PANSS scores at baseline (mean elevation 19.9% Hong Kong, P = 0.016; 14.7% Halifax, P = 0.049). In subjects treated with atypical antipsychotics (all Halifax), EPS+ status at baseline predicted more movement disorders at long term follow up (P = 0.0005). In both cohorts, EPS+ subjects had poorer acute symptomatic treatment response assessed with the PANSS (Hong Kong P = 0.005; Halifax P = 0.017). Neuropsychological impairment related to executive dysfunction appeared greater in a small sam- ple of EPS+ subjects (Hong Kong, effect size 0.26-0.27, P < 0.05). Caudate volumes were 4.5% larger in EPS+ compared with EPS-subjects (Halifax P = 0.042), and correlations between striatal volumes and age were different in the EPS+ group. In conclu- sion, pre-treatment EPS is present in a substantial minority of subjects with first episode psychosis, appears to persist at long term follow up, and is associated with poorer response of symptoms to treatment. Selective impairment of executive function and stria- tal enlargement provides evidence of abnormalities of brain function and structure associated with this aspect of early psychosis.     

JSON在Ajax数据交换中的应用研究

基于Ajax(Asynchronous JavaScript And XML)技术的W eb程序开发和应用主要采用传统的XML数据传输格式,这种数据格式不但会产生大量数据冗余,而且还存在着解析复杂等问题.将XML和JSON进行对比分析,最终选择JSON作为Ajax中的数据传输格式,并用jQuery来解析JSON数据.JSON传输格式可以屏蔽DOM解析XML文件的复杂性,缩短数据传输时间,解决Ajax Web应用系统中数据传输效率优化问题.提出一种Ajax+JSON+jQuery传输方案,通过实例证明这种传输方案能够有效提高W eb应用系统的数据传输效率,减少客户端的请求响应时间.     

成都市商品住宅价格空间分异特征与规律

以成都市商品住宅为研究对象,通过 ＡｒｃＧＩＳ 等方法,研究成都市商品住宅价格空间分异特征和规律。 结果表明:成都 市商品住宅价格总体上呈现出由中心向外围降低的趋势,中心城区主要呈团块状分布,近郊区主要呈放射状分布,远郊区主 要呈星岛状分布;低房价区段在西部—北部—东部地区呈现 ２ 条“半环状”分布;中低房价区段呈“环状＋放射状”分布。 在中 心城区形成了环状分布,在近郊区及远郊区形成了自中心城区向外延伸的放射状分布特征;中房价区段在中心城区分布相对 集中并呈团块状分布,在近郊区呈放射状分布,远郊区呈零星分布特征;中高房价区段在中心城区、高新区、天府新区呈组团 状分布,在近郊区呈放射状分布,远郊区呈零星分布的特征;高房价区段自中心城区沿天府大道向南延伸至天府新区,形成了 南—北走向的峰值带。     

Laser cooling of a nanomechanical oscillator into its quantum ground state

The simple mechanical oscillator, canonically consisting of a coupled mass-spring system, is used in a wide variety of sensitive measurements, including the detection of weak forces and small masses. On the one hand, a classical oscillator has a well-defined amplitude of motion; a quantum oscillator, on the other hand, has a lowest-energy state, or ground state, with a finite-amplitude uncertainty corresponding to zero-point motion. On the macroscopic scale of our everyday experience, owing to interactions with its highly fluctuating thermal environment a mechanical oscillator is filled with many energy quanta and its quantum nature is all but hidden. Recently, in experiments performed at temperatures of a few hundredths of a kelvin, engineered nanomechanical resonators coupled to electrical circuits have been measured to be oscillating in their quantum ground state. These experiments, in addition to providing a glimpse into the underlying quantum behaviour of mesoscopic systems consisting of billions of atoms, represent the initial steps towards the use of mechanical devices as tools for quantum metrology or as a means of coupling hybrid quantum systems. Here we report the development of a coupled, nanoscale optical and mechanical resonator formed in a silicon microchip, in which radiation pressure from a laser is used to cool the mechanical motion down to its quantum ground state (reaching an average phonon occupancy number of 0.85 ± 0.08). This cooling is realized at an environmental temperature of 20?K, roughly one thousand times larger than in previous experiments and paves the way for optical control of mesoscale mechanical oscillators in the quantum regime.     

氢化非晶硅薄膜光吸收谱的恒定光电流测量法

本文报道了光吸收谱的恒定光电流（ＣｏｎｓｔａｎｔＰｈｏｔｏｃｕｒｒｅｎｔＭｅｔｈｏｄ）测量法，并用其测量了高速沉积的氢化非晶硅薄膜（ａ－Ｓｉ：Ｈ）的光吸收谱，同时观测了ＳｔａｅｂｌｅｒＷｒｏｎｓｋｉ（ＳＷ）效应中样品吸收系数的变化。     

关于用拉格朗日乘子法解静力学问题的一点商榷

本文指出在广义坐标下运用拉格朗日待定乘子法求解受完整约束的力学系统的静力学问题时,只能求出平衡位置而不能求出约束力,从而澄清文献[2]中的一个问题。