Specificity of anti-RH serum inhibition by lipid extracts as determined by quantitative nitrogen assays

Zusammenfassung Eine Reihe der Lipidfraktionen von Rh-positiv und Rh-negativ (D-positiv und D-negativ) roten Zellen menschlichen Blutes wurde der Wirkung von anti-Rho Serum (anti-D) ausgesetzt. Die dabei adsorbierte Menge von Stickstoff wurde quantitativ bestimmt. In jedem Fall adsorbierten die Lipide von Rh-positiv roten Zellen mehr Antikörperstickstoff als die aus Rh-negativ roten Zellen extrahierten Lipide. Man darf wohl daraus schliessen, dass der höhere Grad der Adsorption von Antikörperstickstoff auf Lipiden von Rh positiv roten Zellen ein spezifischer Effekt ist.     

Behavioural consequences of vasectomy in the mouse

Summary Vasectomy was found to have no influence on the sexual activity of male mice. Testis and seminal vesicle weights were similary not influenced by this operation although a significant increase in epididymus weight was observed.J. C. is grateful to the Ford Foundation for financial support.     

Factors influencing fish assemblages of a high-elevation desert stream system in Wyoming

Seven fish species were found in the Bitter Creek drainage of southwest Wyoming, but only speckled dace ( Rhinichthys osculus ), flannelmouth sucker ( Catostomus latipinnis ), and mountain sucker ( Catostomus platyrhynchus ) were indigenous. No relationships were found between fish standing stocks and habitat features, but species richness was related to elevation and stream width. No fish were found above an elevation of 2192 m. Only the most downstream study read had more than three species present. Two indigenous species, speckled dace and mountain sucker, and a nonnative species, fathead minnow ( Pimephales promelas ), were predominant fishes in the drainage. These three species withstand intermittent stream flows that are common in the drainage.     

Atomic structure and chemistry of human serum albumin.

The three-dimensional structure of human serum albumin has been determined crystallographically to a resolution of 2.8 A. It comprises three homologous domains that assemble to form a heart-shaped molecule. Each domain is a product of two subdomains that possess common structural motifs. The principal regions of ligand binding to human serum albumin are located in hydrophobic cavities in subdomains IIA and IIIA, which exhibit similar chemistry. The structure explains numerous physical phenomena and should provide insight into future pharmacokinetic and genetically engineered therapeutic applications of serum albumin.     

污泥龄对活性污泥处理微量磺胺类药物的影响

为了研究污泥龄对活性污泥系统处理微量磺胺类药物（5 μg/L）的影响,共运行了4个试验室规模（3L）的序批式活性污泥反应器（SBR）,其污泥龄分别为2、8、14、20 d。批次摇瓶试验通过设置3个工况（正常运行,加入生物抑制剂,无微生物）来讨论在1个运行周期（8 h）中对浓度惟5 μg/L磺胺甲恶唑的吸附作用、生物降解作用和挥发损失。试验结果显示对磺胺甲恶唑的总去除量为2.14 ± 0.60 μg/g SS,吸附作用占总去除量的63%;磺胺嘧啶为1.14 ± 0.63 μg/g SS,83%;磺胺间二甲氧为2.33± 0.67 μg/g SS, 35%;磺胺甲基嘧啶为2.45 ± 0.85 μg/g SS,55%;磺胺类药物的去除效果与污泥的污泥龄有着非常显著的关系（p<0.02）。通过运行加入磺胺甲恶唑（进水5 μg/L)的反应器60 d,4个反应器对磺胺甲恶唑的平均去除率分别为10%、41%、51%、58%,处理效果随着污泥龄的增加而变好,同时单位污泥去除率随着污泥龄的增加而降低,SRT=2 d的反应器由于存在大量的丝状菌,使得单位污泥对磺胺甲恶唑去除率大大高于其他3个反应器。通过分子生物学分析,发现微生物群落结构的变化不大,从而说明了影响磺胺类药物处理效果的主要因素在于更强的吸附能力,更高的污泥浓度。