发电机转子同步稳定性的非线性分析

以与弱联电网相连的单机系统为对象,研究发电机转子摇摆的非线性稳定性问题·用微分方程几何理论的后继函数方法,判别了非线性摇摆方程的中心奇点的稳定性,并应用多尺度法求解了摇摆方程,得到了方程的二次近似稳态解·分析了电网扰动参数对转子响应的影响,发现了在不同扰动参数下转子响应呈现复杂的分叉与混沌运动,为弱联电力系统的稳定性提供了判据·     

B_4C粉末的气流粉碎及烧结

采用气流粉碎对B4C粗粉 (比表面积为 0 5 2m2 g,中位粒度为 2 0 4μm)进行粉碎实验 ,研究了气流粉碎次数对粉末性能、压坯密度和烧结密度的影响及成形压力和烧结温度对B4C烧结密度的影响 .研究结果表明 :当粉碎次数达到 3次后 ,可获得中位粒度小于 1μm的B4C超细粉末 ;经过 4次气流粉碎的B4C超细粉末 ,其比表面积为2 5 3m2 g ,中位粒度为 0 5 6 μm ;该粉末于 2 2 5 0℃无压烧结 1h ,其烧结密度为 2 0 7g cm3 ,达到理论密度的82 .5 % ,平均晶粒粒度为 5 0 μm .可见 ,气流粉碎能改善B4C的烧结性 .     

U-CDP-1,1'二甲基二茂铁主客体葡萄糖生物传感器

选用β环糊精与戊二醛缩合成的β环糊精聚合物（β Ｃ Ｄ Ｐ）为主体,电媒介体 １,１＇二甲基二茂铁为客体,形成稳定的主客体包络物．用牛血清白蛋白戊二醛交联法,把葡萄糖氧化酶和主客体包络物固定到电极上,成功地制成了葡萄糖生物传感器．该传感器具有稳定性高、选择性好和较长的使用寿命等优点,线性响应范围为０．０１～１８ｍ ｍ ｏｌ／ Ｌ．     

LDPE含量对LLDPE/LDPE共混物性能的影响

以线性低密度聚乙烯(LLDPE)与低密度聚乙烯(LDPE)为原料,经Brabender挤出机熔融吹膜制备出LLDPE/LDPE共混膜,并借助差示扫描量热仪(DSC)、偏光显微镜(POM)、电子万能试验机和毛细管流变仪研究了LLDPE/LDPE共混物的结晶行为、结晶形态、力学性能以及熔体流变性能.结果表明:加入适量LDPE后,共混膜仍然具有较好的综合力学性能.随着LDPE质量分数的增加,共混物的结晶度下降,晶粒尺寸减小;共混物的熔体流变性能提高.     

机械零件图像中直线边缘亚像素定位方法

以计算机视觉在机械零件几何参数检测的实际应用为例，提出了一种使用高斯拉普拉斯(LOG)函数检测斜坡状边缘的像素级位置，在已知目标为直线边缘的情况下，使用最小二乘线性回归把二维的边缘拟合降为一维边缘定位，从而使直线边缘定位达到亚像素级精度的算法．同时还进行了空间矩直线边缘亚像素定位算法与本文所提出算法的对比实验．实验结果表明：在低噪声图像中，两种算法的边缘定位精度均达到满意的结果，且最小二乘线性回归亚像素定位算法速度较快．     

智能结构压电执行器位置的拓扑优化

提出了一种选取压电执行器优化位置的拓扑优化方法·其基本思想是利用可控矩阵的奇异值单元灵敏度来识别压电执行器优化位置·讨论了智能结构模态可控性的度量问题;推导了可控矩阵奇异值单元灵敏度公式;给出了确定压电执行器优化位置的优化准则;用算例说明了方法的有效性·     

长柄扁桃种仁蛋白粉的提取方法研究

目的以长柄扁桃种仁为原料,对植物蛋白粉的提取方法和沉淀方法进行研究,通过单因素实验确定蛋白粉最佳提取工艺。方法分别考察了碱提蛋白法、水提蛋白法和盐提蛋白法3种提取方法,及酸沉法、醇沉法和盐沉法3种蛋白沉淀方法;考察提取时间、提取温度及料液比对蛋白提取率的影响。结果单因素实验确定水提法最佳提取条件为:温度30℃,时间50min,料液比1:9,在此条件下,蛋白提取率为50.7%。蛋白粉中蛋白质量分数达94.8%,脂肪仅为0.96%。结论水提酸沉法为长柄扁桃蛋白粉实验室最佳提取方法。     

Association of a functional variant downstream of TNFAIP3 with systemic lupus erythematosus

Systemic lupus erythematosus (SLE, MIM152700) is an autoimmune disease characterized by self-reactive antibodies resulting in systemic inflammation and organ failure. TNFAIP3, encoding the ubiquitin-modifying enzyme A20, is an established susceptibility locus for SLE. By fine mapping and genomic re-sequencing in ethnically diverse populations, we fully characterized the TNFAIP3 risk haplotype and identified a TT>A polymorphic dinucleotide (deletion T followed by a T to A transversion) associated with SLE in subjects of European (P = 1.58 × 10(-8), odds ratio = 1.70) and Korean (P = 8.33 × 10(-10), odds ratio = 2.54) ancestry. This variant, located in a region of high conservation and regulatory potential, bound a nuclear protein complex composed of NF-κB subunits with reduced avidity. Further, compared with the non-risk haplotype, the haplotype carrying this variant resulted in reduced TNFAIP3 mRNA and A20 protein expression. These results establish this TT>A variant as the most likely functional polymorphism responsible for the association between TNFAIP3 and SLE.     

基于粗糙集理论的内燃机故障诊断专家系统

在故障诊断专家系统的基础上,引入粗糙集理论,并以信息系统属性值表为主要工具,专家系统中的规则进行约简并剔除不必要的属性,揭示了故障诊断信息中内的冗余性,降低了故障诊断专家系统构成的复杂性,并建立了简化后的决策规则。     

Human papillomavirus 16 E5 up-regulates the expression of vascular endothelial growth factor through the activation of epidermal growth factor receptor, MEK/ ERK1,2 and PI3K/Akt

The E5 oncoprotein of human papillomavirus (HPV) 16 plays an important role in early cervical carcinogenesis. Vascular endothelial growth factor (VEGF) plays a central role in switching on the angiogenic phenotype during early cervical carcinogenesis. However, the relationship between E5 and VEGF has not previously been examined. To clarify the regulatory role of E5 in VEGF expression, we transferred the E5 gene into various cell types. E5 increased VEGF expression. The addition of epidermal growth factor receptor (EGFR) inhibitor significantly suppressed VEGF expression, demonstrating that E5 stimulates VEGF expression through the activation of EGFR. E5-mediated EGFR activation was accompanied by phosphorylation of Akt and ERK1/2, which are also involved in VEGF expression. Furthermore, the mRNA stability of VEGF was not affected by E5, but VEGF promoter activity could be modulated by inhibitors of the EGFR, MEK-ERK1/2 and PI3K/Akt pathways in E5-expressing cells. Collectively, these novel results suggest that HPV 16 E5 increases VEGF expression by activating EGFR, MEK/ERK1/2 and PI3K/Akt. Received 23 November 2005; received after revision 10 January 2006; accepted 9 February 2006