Effects of L-lysine administration on certain aspects of ascorbic acid metabolism in weanling rats

Summary L-lysine administration to male weanling rats at a dose of 110.4 mg (25% LD₅₀) per 100 g body weight per day for 15 days reduced the liver total ascorbic acid level. The biosynthesis as well as the degradation of L-ascorbic acid was diminished under these conditions. The fall in liver total ascorbic acid level after L-lysine administration was ascribed to its reduced synthesis.Acknowledgment. The authors are thankful to the Council of Scientific and Industrial Research, India, for providing Junior Research Fellowships to Miss J. Basu and Miss K. Sen Gupta.     

Liposomes as immunological carriers for the preparation of antimannosyl antibodies

Summary Antiserum was raised against an aminophenyl derivative of D-mannose grafted on to a liposomal surface. As characterized by immunodiffucion, quantitative precipitation and hapten inhibition, the antiserum was found to contain mannose specific antibodies in addition to antibodies against the aromatic phenyl group. Acknowledgment. We would like to thank Mr S. Kumar Roy for his excellen technical assistance.     

The effect of lithium ions on the post-tetanic potentiation of neuro-muscular transmission

Zusammenfassung Am partiell curarisierten Zwerchfell-Phrenicus-Präparat des Meerschweinchens wurde gefunden, dass die post-tetanische Fazilitation auch in Lihaltiger Lösung auftritt. Die Fazilitation scheint nicht durch post-tetanische Hyperpolarisation entstanden zu sein, da diese nach Li-Applikation ausbleibt.