新型多开关脉冲功率技术

摘要阐述一种基于TLT(Transmission-Line-Transformer)的新型多开关脉冲功率技术。该技术可以像Marx发生器一样实现多个火花开关的自动同步,而无需外部同步触发电路或光路。与传统的多开关电路相比,不仅可以通过电压叠加获得高电压输出,而且可以通过电流叠加实现大电流输出,或者用于驱动多个独立的负载。该技术已被成功应用于高效高重复率大功率纳秒短脉冲电源的开发。该电源采用10个火花开关,它们可以在约10nm内实现同步。输出脉冲上升沿约10ns,脉冲宽度55ns。输出峰值功率300～810MW,输出电压40～77kV,输出电流6～11kA,能量转换效率93%～98%。由于总的开关负荷由10个开关均分,与基于单个火花开关的系统相比,系统寿命可大幅度提高。当采用闸流管时,还可以用来产生大电流微秒脉冲,可行性已经在具有3个闸流管的小型实验设备上得到验证。此外,该技术独特的多开关连接方式可以拓展到其他脉冲电路中,如Blumlein发生器和感应叠加器,从而派生出其他新型多开关电路。     

Adaptation of Industrial Organisations to the Environment Grounded in Evolutionary Models

Yes, we perceive that the environment in which comp an ies operate, is changing at higher speeds then before. Globalisation, higher inn ovation rates, customisation, more intense competition, technological developmen ts account for these changes effecting the way industrial companies operate and eventually their structures and processes. Companies have to adapt themselves to these changes. The question arose whether the approach of the Section Industria l Organisation and Management that it has practised ...     

Mutations in the gene encoding mevalonate kinase cause hyper-IgD and periodic fever syndrome. International Hyper-IgD Study Group.

Hyperimmunoglobulinaemia D and periodic fever syndrome (HIDS; MIM 260920) is a rare, apparently monogenic, autosomal recessive disorder characterized by recurrent episodes of fever accompanied with lymphadenopathy, abdominal distress, joint involvement and skin lesions. All patients have high serum IgD values (>100 U/ml) and HIDS 'attacks' are associated with an intense acute phase reaction whose exact pathophysiology remains obscure. Two other hereditary febrile disorders have been described. Familial Mediterranean fever (MIM 249100) is an autosomal recessive disorder affecting mostly populations from the Mediterranean basin and is caused by mutations in the gene MEFV (refs 5,6). Familial Hibernian fever (MIM 142680), also known as autosomal dominant familial recurrent fever, is caused by missense mutations in the gene encoding type I tumour necrosis factor receptor. Here we perform a genome-wide search to map the HIDS gene. Haplotype analysis placed the gene at 12q24 between D12S330 and D12S79. We identified the gene MVK, encoding mevalonate kinase (MK, ATP:mevalonate 5-phosphotransferase; EC 2.7.1.36), as a candidate gene. We characterized 3 missense mutations, a 92-bp loss stemming from a deletion or from exon skipping, and the absence of expression of one allele. Functional analysis demonstrated diminished MK activity in fibroblasts from HIDS patients. Our data establish MVK as the gene responsible for HIDS.     

Metamodeling: The epistemology of system science

The Metasystem Paradigm postulates a hierarchy of at least three inquiring systems: at the lowest level of abstraction, an inquiring system devoted to IMPLEMENTATION; at the object level, an inquiring system devoted to MODELING; and finally, at the metalevel, an inquiring system devoted to METAMODELING. System Design is incomplete without the intervention of these three inquiring systems, each of which plays a role in System Design. System Science draws its paradigm and its epistemology from the metalevel inquiring system. Furthermore, this inquiring system is dedicated to a methodology called METAMODELING which provides MODELING (at the next-lower inquiring system) with its source of knowledge and its reasoning methods. A design is incomplete unless it takes into account both MODELING and METAMODELING. METAMODELING is to MODELING what the Theory of Design is to Design, or what Decision Making ABOUT Decision Making is to Decision Making, or what Learning to Learn is to Learning. The consequences of using an obsolete modeling paradigm are explored in relation to the discipline of operations research.     

Martian stepped-delta formation by rapid water release

Deltas and alluvial fans preserved on the surface of Mars provide an important record of surface water flow. Understanding how surface water flow could have produced the observed morphology is fundamental to understanding the history of water on Mars. To date, morphological studies have provided only minimum time estimates for the longevity of martian hydrologic events, which range from decades to millions of years. Here we use sand flume studies to show that the distinct morphology of martian stepped (terraced) deltas could only have originated from a single basin-filling event on a timescale of tens of years. Stepped deltas therefore provide a minimum and maximum constraint on the duration and magnitude of some surface flows on Mars. We estimate that the amount of water required to fill the basin and deposit the delta is comparable to the amount of water discharged by large terrestrial rivers, such as the Mississippi. The massive discharge, short timescale, and the associated short canyon lengths favour the hypothesis that stepped fans are terraced delta deposits draped over an alluvial fan and formed by water released suddenly from subsurface storage.     

The first hominin of Europe

The earliest hominin occupation of Europe is one of the most debated topics in palaeoanthropology. However, the purportedly oldest of the Early Pleistocene sites in Eurasia lack precise age control and contain stone tools rather than human fossil remains. Here we report the discovery of a human mandible associated with an assemblage of Mode 1 lithic tools and faunal remains bearing traces of hominin processing, in stratigraphic level TE9 at the site of the Sima del Elefante, Atapuerca, Spain. Level TE9 has been dated to the Early Pleistocene (approximately 1.2-1.1 Myr), based on a combination of palaeomagnetism, cosmogenic nuclides and biostratigraphy. The Sima del Elefante site thus emerges as the oldest, most accurately dated record of human occupation in Europe, to our knowledge. The study of the human mandible suggests that the first settlement of Western Europe could be related to an early demographic expansion out of Africa. The new evidence, with previous findings in other Atapuerca sites (level TD6 from Gran Dolina), also suggests that a speciation event occurred in this extreme area of the Eurasian continent during the Early Pleistocene, initiating the hominin lineage represented by the TE9 and TD6 hominins.