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91.
Summary An intermediate stage between the elementary and the initial bodies of theRickettsiella genus is defined as the beginning of an intracellular cycle. It is characterized by several structural changes in the dense elementary body: the cytoplasm becomes less electron-dense; thus, the nucleoid and the ribosomes are visible. The inner layer of the cell-wall becomes progressively clearer and the trilamellar structure of the inner and outer membranes appears distinctly. Preinitial body is proposed as name of this stage of development. 相似文献
92.
Summary Viable cerebellar perikarya of mixed cell type obtained from 7–9-day-old rats were maintained in monolayer culture for up to 12 days. During this time extensive neurite formation and outgrowth occurred. The large majority of the cells developing in culture were tentatively identified as granule neurons. This identification was based on the large number isolated from the starting tissue, and the cells general morphological features in culture such as perikaryal and nuclear size, the bipolar nature of neurite extension, and their migratory behaviour.D.N. Currie was supported by a grant from Hoechst Pharmaceuticals, Ld, U.K.J.C. was supported by an S.R.C. Grant to S.P.R. RoseThe authors would like to thank Kathleen Tear for excellent technical assistance and members of the Brain Research Group for helpful discussions. 相似文献
93.
F. Caviezel M. Poli A. M. Girardi G. Pozza 《Cellular and molecular life sciences : CMLS》1979,35(10):1402-1404
Summary The insulinemic response to 1 g of tolbutamide i.v. is greatly enhanced (+145%) after a 60-min infusion of the -lytic dihydrogenated ergot alkaloid, dihydroergocristine (83.3 m/min, corresponding to a total dose of 5 mg) in 7 healthy subjects. No differences are observed in the glycemic responses.Acknowledgment. The authors are grateful to Mr Franco Della Sala, M.D., for his skillful technical assistance. 相似文献
94.
Summary In 10 human subjects plasma dopamine--hydroxylase activity was found in the adrenal vein blood to be as high as in the periphery of the circulation. Adrenaline concentration in the adrenal vein blood was in the mean 170 times, noradrenaline concentration 11 times and dopamine concentration little higher than levels in the periphery.This study was supported by the Deutsche Forschungsgemeinschaft. 相似文献
95.
Non-encephalitogenic antigen-induced suppression and reversal of allergic encephalomyelitis. 总被引:1,自引:0,他引:1
G A Hashim 《Nature》1975,256(5518):953-955
96.
97.
G. M. Hanozet M. Simonetta D. Barisio A. Guerritore 《Cellular and molecular life sciences : CMLS》1976,32(10):1246-1249
Summary The three enzymes of ethanol metabolism alcohol dehydrogenase, aldehyde dehydrogenase and acetyl-CoA synthetase in the obligate aerobic yeastRhodotorula gracilis are repressed by glucose and induced by C2 metabolic fuels with a regulatory pattern indicating a correlation in the control mechanisms. To try an identification of the molecular signals involved in the transmission of the inducing stimulus, experiments were carried out by blocking with 2 mM pyrazole the ethanol acetaldehyde metabolic step. Results indicate that ethanol is not specifically required as a molecular signal for induction.This work was supported by a grant from the Italian Consiglio Nazionale delle Ricerche. 相似文献
98.
Summary Rat brain mitochondria contain a significant proportion of poly(A) associated RNA which is higher than that found in microsomes from the same source. When steady state poly(A) RNA of brain mitochondria was analyzed by microelectrophoresis, it displayed a characteristic separation pattern with a large amount of free poly(A). 相似文献
99.
R. G. G. Andersson H. J. Arnqvist L. Lundholm 《Cellular and molecular life sciences : CMLS》1976,32(5):601-602
Summary The incorporation of leucice-14C into protein in bovine mesenteric arteries was augmented by cyclic GMP (10–3
M) and decreased by cyclic AMP (10–3
M). There was no effect of 5 AMP (10–3
M). The phosphodiesterase inhibiting drugs theophylline (10–3
M) and papaverine (5×10–5 g/ml) both decreased the leucine-14C incorporation.We are indebted to Mrs.Lena Burlin for hear assistance. Finacial support has been provided by the Swedish State Medical Research Council (No. 04X-101X-4498). 相似文献
100.
Summary The effect of negative and positive air ionisation on siliconized blood serotonin was studied in vitro. The experiments showed that within 10 min positive ionisation increased serotonin levels in total blood (+40%), plasma (+90%), erythrocytes (+50%) and thrombocytes (+200%). On the other hand, negative ionization (10 min) lowered the serotonin content of total blood (–30%), plasma (–42.5%), erythrocytes (–41.7%) and thrombocytes (–72.3%), thus confirming the Krueger Effect in vitro.This research was generously supported by a grant from the Joint Research Fund of the Hebrew University and Hadassah, and Dr. and Mrs.Leonard Appleby of Palmbeach, Florida.Acknowledgment: Our thanks are due to Mr.B. Shalita, Mrs.Zippora Adar and Mrs.Olga Fradkin for devoted technical assistance. 相似文献