枯草杆菌AS1．398制备中性蛋白酶的研究

本文研究了枯草杆菌ＡＳ１．３９８发酵培养制备中性蛋白酶，对发酵培养基配比，培养条件，金属离子的影响等进行了摇瓶试验。制备的ＡＳ１．３９８中性蛋白酶有如下性质：最适ＰＨ７．２－７．４，在ＰＨ６．５－８．０稳定。最适温度４２－４４℃，３５℃下处理２小时能保持约８５％酶活力，６０℃下１０分钟酶完全失活，此酶被ＥＤＴＡ和Ｃｕ２＋所抑制     

通风系统灵敏度分析

从通风系统的风量调控需要出发,研究了风量对风阻变化的灵敏度的数学模型,简化了灵敏度的计算方法,分析了灵敏度矩阵的性质及灵敏度在通风系统分析中的作用和意义,为矿井通风管理和灾变处理提供了有效参数。     

DNA fingerprinting transforms the art of cell authentication.

The increasing diversity of new cell cultures is seriously stretching the capabilities of traditional methods of identification. DNA fingerprinting is set to play an important role in increasing confidence in the authenticity of cultures in research and industry.     

全息正弦式波带片特性研究

本文主要对全息正弦式波带片的形成及成像特性进行了详细的理论分析，并把它与传统的菲氏波带片及几何光学透镜作比较研究，从中获得正弦式波带片的焦距公式；ｆ＝λ１α／λ２。     

武汉地区网纹层的若干问题

根据大量钻孔和开挖剖面的资料,对武汉地区网纹层的剖面特征、物质组成、孢粉组合、成因以及其与新构造运动的关系,作了初步的论述。     

有关α-对称分布的几个结果

本文综合运用特征函数理论和随机分解方法研究了α-对称分布,得到了一系列结果,为α-对称分布问题的最后彻底解决提供了一些基础性工作。     

一个非线性互补问题

本文给出了局部一致凸自反的 Banach 空间上互补问题的一个解的存在性定理。这个结果是在较弱的 Karmardian 条件下得到的。     

Prediction of the structure of a receptor-protein complex using a binary docking method.

To validate procedures of rational drug design, it is important to develop computational methods that predict binding sites between a protein and a ligand molecule. Many small molecules have been tested using such programs, but examination of protein-protein and peptide-protein interactions has been sparse. We were able to test such applications once the structures of both the maltose-binding protein (MBP) and the ligand-binding domain of the aspartate receptor, which binds MBP, became available. Here we predict the binding site of MBP to its receptor using a 'binary docking' technique in which two MBP octapeptide sequences containing mutations that eliminate maltose chemotaxis are independently docked to the receptor. The peptides in the docked solutions superimpose on their original positions in the structure of MBP and allow the formation of an MBP-receptor complex. The consistency of the computational and biological results supports this approach for predicting protein-protein and peptide-protein interactions.