Exponential smoothing: Behavior of the ex-post sum of squares near 0 and 1

When using simple exponential smoothing on a given time series the nature of the relationship between the optimal smoothing constant and the autocorrelation structure of the series remains an unresolved question. Although numerical search routines can easily be used to find optimal values of the smoothing constant, they offer little insight into the nature of the relationship between the estimated smoothing constant and the structure of the underlying time series. We suggest that renewed investigations of the ex-post sum of squares function may prove helpful in this pursuit. Results are presented that illustrate how the optimal smoothing constant depends upon the value used to initialize the smoothing and upon the sample autocorrelation coefficients of the observed series. These results are based on a new formula for the derivative of the ex-post sum of squares function. In particular, the derivative is examined near 0 and 1, where great simplifications occur in its form, thereby facilitating investigations near these points. A necessary and sufficient condition is stated for when the ex-post sum of squares must have a positive derivative at 0 and the autocorrelation coefficients of the differenced series are shown to affect the sign of the derivative near 1. Based on these results, a general algorithm is presented as an alternative to grid search routines for minimizing the ex-post sum of squares.     

Effect of volatile anesthetics on the circular dichroism of bilirubin bound to human serum albumin

The characteristic circular dichroism of bilirubin bound to human serum albumin undergoes a remarkable sign inversion on addition of halothane, chloroform and other volatile anesthetics. This sign inversion, which is completely reversed by removal of the anesthetic, reflects a pronounced conformational change of the bound ligand; probably a complete inversion of chirality. The observation suggests that association of volatile anesthetics with proteins can markedly alter the internal topography of receptor sites and potentially influence the stereoselectivity of ligand binding.     

微机字处理软件CAI开发方法的研究

本文阐述了研究计算机软件ＣＡＩ开发方法学的意义，并介绍了字处理软件Ｗｏｒｄｓｔａｒ的教学软件的开发方法．     

实时实现MPEG2运动估计的DSP处理系统

本文根据ＭＰＥＧ２的图像标准与要求，利用若干大规模集成电路芯片，设计了实时实现活动图像运动估计的ＤＳＰ处理系统板，通过序列图像的测试，证明其工作正常，性能可靠，完全符合ＭＰＥＧ２的技术规范，从而为我国近期实现ＭＰＥＧ２的编解码系统、乃至ＨＤＴＶ实验系统在硬件方面打下了良好的基础。     

负反馈电桥在电阻传感器线性化中的应用

本文介绍利用信号流图及梅森公式分析设计负反馈电桥电路,以及在电阻传感器测量线性化中的应用。     

Estimation and testing of time-varying coefficient regression models in the presence of linear restrictions

A linear regression model with random walk coefficients is extended to allow for linear restrictions between the coefficients to be satisfied at each point in time. Estimation in this model is shown to be no more involved than estimation in the standard model. It is also demonstrated how, after a slight modification to the testing problem, classical test procedures may be applied to the problem of testing for such restrictions. The performance of the Lagrange Multiplier test for a variety of different restrictions is then investigated via simulation. An empirical application involving testing for homogeneity in a random walk coefficient version of the AIDS model is given.     

Nuclear localization and signalling activity of phosphoinositidase C beta in Swiss 3T3 cells.

The hydrolysis of phosphatidylinositol 4,5-bisphosphate (PtdInsP2) is a widespread receptor-coupled signalling system at the plasma membrane of most eukaryotic cells. The existence of an entirely separate nuclear phosphoinositide signalling system is suggested from evidence that purified nuclei synthesize PtdInsP2 and phosphatidylinositol 4-phosphate (PtdInsP) in vitro and that a transient decrease in the mass of these lipids occurs when Swiss 3T3 cells are cultured in the presence of insulin-like growth factor-1 (IGF-1). These IGF-1-dependent changes in inositol lipids coincide with an increase in nuclear diacyglycerol and precede translocation to the nucleus and activation of protein kinase C (refs 5, 6). Circumstantial evidence that links these changes with mitosis comes from the isolation of a 3T3 clone that expresses the type-1 IGF receptor and binds IGF-1 peptide but does not respond mitogenically or show transient mass changes in nuclear inositol lipids. A key question is how IGF-1 initiates the rapid breakdown of PtdInsP and PtdInsP2 in the nucleus. Here we present evidence that nuclei of 3T3 cells contain the beta-isozyme of phosphoinositidase C, whereas the gamma-isozyme is confined to the cytoplasm and that IGF-1 treatment stimulates exclusively the activity of nuclear phosphoinositidase C.     

磁光光盘动态性能的研究

该文报道了所研制的具有AIN/TbFeCo/AIN/AI四层结构磁光光盘的动态性能测试结果.当记录信息位尺寸为1μm时,信息读出载噪比大于45dB,载噪比随盘片径向位置而异.文中根据测试结果,讨论了影响载噪比的诸因素.     

光纤色散与OFDL信号处理

光纤色散对OFDL器件功能的影响并不总能忽略。对OFDL陷波器,在现有器件水平下,由于色散ND只能达到30dB左右,远低于测量系统的限制(>55dB)。利用陷波器,也可以测量光纤色散、该方法具有步骤简便、对器件要求低、精度高等优点。     

数据采集与光条图象细化新方法——用于三维计算机视觉系统

介绍了具有位置反馈信息旋转平台的图象数据采集方法,以及对采集到的图象进行智能化快速细化的新方法,使得在一周内的36幅图象做到边采集边细化,而且仅用40s时间。