Single injections of triazolam,a short-acting benzodiazepine,lengthen the period of the circadian activity rhythm in golden hamsters

Single injections of the benzodiazepine, triazolam, induce phase shifts and cause a lengthening of the circadian activity rhythm in the golden hamster. The effect of triazolam on period depends on the phase of injection, but is not dependent on the direction of the phase shifts. Triazolam injections caused increases in period that were associated with phase advances as well as phase delays in the activity rhythm. This relationship between triazolam-induced phase shifts and changes in period is different from the relationship between light-induced phase shifts and period changes.     

Secondary metabolites of the chemically rich ascoglossanCyerce nigricans

Summary Two new metabolites of an apparent propionate origin have been isolated from the organic extract of the ascoglossan molluscCyerce nigricans. The proposed structures for the new natural products are based on interpretation of their physical and spectral properties. The new compounds isolated lacked the potent ichthyodeterrent properties of the whole animal extract suggesting that other molecules are involved in the defense of this shell-less mollusc.     

Isoprenaline-like effects of the phosphodiesterase inhibitor 3-isobutyl-1-methylxanthine on mechanical, biochemical and electrophysiological parameters in the mammalian heart

The phosphodiesterase inhibitor 3-isobutyl-1-methylxanthine (IBMX) mimicked the effects of isoprenaline on the force of contraction, the cAMP content and the slow Ca++ inward current (Isi) in isolated guinea pig papillary muscles. The results support the hypothesis that phosphodiesterase inhibitors and beta-adrenoceptor agonists exert their positive inotropic effects by increasing Isi via the common mediator cAMP.     

高炉全偏心型贯流式风口结构对其寿命的影响

针对鞍钢炼铁厂全偏心型贯流式高炉风口的生产实践,对风口内冷却水流场、风口温度场及应力场进行了三维数值模拟并提出了改进对策.研究了不同给水工艺参数对全偏心型贯流式高炉风口寿命的影响,找出了易发生冷却死区的部位并通过改进其部分结构消除了冷却死区,又将风口端部冷却水通道由原半圆形改为半椭圆形,结果表明能使风口端部温度分布更均匀,降低了风口端部的最高温度,从而有效提高了风口寿命.     

浅谈制约文献传递服务的因素及其对策

从文传观念、文传系统、文传模式、文传人员及文传技术设备等方面分析了制约文献传递服务的因素,探讨了克服这些制约因素的对策。     

Verapamil和Propranolol对非胰岛素依赖型糖尿病透析患者物质代谢的影响

比较Ｖｅｒａｐａｍｉｌ和Ｐｒｏｐｒａｎｏｌｏｌ对患有胰岛素非依赖型糖尿病及轻度至中度高血压的透析患者的血糖和物质代谢的影响。方法：４６例患有非胰岛素依赖型糖尿病及轻度至中度高血压的透析患者，为德国福尔达市ＫｆＨ血透中心和柏林ＫｆＨ血透中心的透析病人。分别经Ｖｅｒａｐａｍｉｌ和Ｐｒｏｐｒａｎｏｌｏｌ治疗三个月后测空腹血糖、血红蛋白Ａ１ｃ、果酸、胰岛素、胆固醇和甘油三脂，同时记录透析前心率和血压。结果：Ｖｅｒａｐａｍｉｌ对血糖及物质代谢无不良影响，Ｐｒｏｐｒａｎｏｌｏｌ可引起血糖、果酸和血红蛋白Ａ１ｃ升高。结论：在糖尿病透析患者，Ｐｒｏｐｒａｎｏｌｏｌ具有引起和／或加重小动脉血管病病以及脑血管意外的危险性     

诧城发电厂输煤计算机控制系统总体结构

该文论述了诧城发电厂输煤计算机控制系统的设计流程，总体配置，网络构成和软件结构２，该系统采用了带远程Ｉ／Ｏ工作站的计算机控制系统，并配置了上位机图形监控系统的实时管理系统。该系统已在该电厂输煤线成功地运行了２年多。在软件编程中，采用级式语言，有效地缩短系统扫描时间和响应时间。