利用14N(d，p)15N核反应对各品系小麦种子中蛋白质含量分析初探

粮食作物提供的植物蛋白是人体所需要的蛋白质中最基本、最重要的来源 ,提高粮食作物中的蛋白质含量 ,对改善食品质量、提高营养水平有着重要意义 ,国际上一直把改善谷物蛋白质含量作为重要研究课题 .测定植物样品中蛋白质含量的传统方法是Ｋ氏 (Ｋｊｅｌｄａｈｌ)化学分析法 ,但Ｋ氏法是破坏性的 ,同时又很费时 ,难以满足在选种培育计划中对大批量样品进行快速分析的需要 .因此由基于对氮元素成分的分析出发 ,从而促进了确定蛋白质含量的核技术在这一需求下得到迅速的发展[1] ,如快中子活化法、热中子活化法、光子活化分析法和由质子、α粒…     

Selected decrease of haemocytes of the freshwater snail Planorbarius corneus (L.) (Gastropoda, Pulmonata) after bacteria injection

The decrease of haemolymph phagocytic cells (SH) in Planorbarius corneus after bacterial injection seems to be mediated by humoral factor(s) released into the haemolymph. SH show different adhesiveness in vitro in the presence of bacterial metabolic products.     

On the Difficulty of Measuring Forecasting Skill in Financial Markets

The use of correlation between forecasts and actual returns is commonplace in the literature, often used as a measurement of investors' skill. A prominent application of this is the concept of the information coefficient (IC). Not only can the IC be used as a tool to rate analysts and fund managers but it also represents an important parameter in the asset allocation and portfolio construction process. Nevertheless, a theoretical understanding of it has typically been limited to the partial equilibrium context where the investing activities of each agent have no effect on other market participants. In this paper we show that this can be an undesirable oversimplification and we demonstrate plausible circumstances in which conventional empirical measurements of IC can be highly misleading. We suggest that improved understanding of IC in a general equilibrium setting can lead to refined portfolio decision making ex ante and more informative analysis of performance ex post. Copyright © 2015 John Wiley & Sons, Ltd.     

The curvature argument

Dasgupta (2015) has recently put forward a novel argument, which he calls the ‘curvature argument’, that aims to show that Galilean spacetime is not an ideal setting for our classical theory of motion. This paper examines the curvature argument and argues that it is not sound. The discussion yields a remark about the conditions under which a ‘symmetry argument’ demonstrates that a particular spacetime is a non-ideal setting for our theory of motion.     

Old drugs with new skills: fenoprofen as an allosteric enhancer at melanocortin receptor 3

The efficiency of drug research and development has paradoxically declined over the last decades despite major scientific and technological advances, promoting new cost-effective strategies such as drug repositioning by systematic screening for new actions of known drugs. Here, we performed a screening for positive allosteric modulators (PAMs) at melanocortin (MC) receptors. The non-steroidal anti-inflammatory drug fenoprofen, but not the similar compound ibuprofen, presented PAM activity at MC₃, MC₄, and MC₅ receptors. In a model of inflammatory arthritis, fenoprofen afforded potent inhibition while ibuprofen was nearly inactive. Fenoprofen presented anti-arthritic actions on cartilage integrity and synovitis, effects markedly attenuated in Mc3r?/? mice. Fenoprofen displayed pro-resolving properties promoting macrophage phagocytosis and efferocytosis, independently of cyclooxygenase inhibition. In conclusion, combining repositioning with advances in G-protein coupled receptor biology (allosterism) may lead to potential new therapeutics. In addition, MC₃ PAMs emerged as a viable approach to the development of innovative therapeutics for joint diseases.