网络信息时代个人隐私面临的挑战与对策

计算机技术给人们的工作环境带来了质的变化，而这种高效便捷工作环境的获得是以人们丧失部分个人隐私权为代价的。从隐私权的概念出发，首先分析了计算机网络技术的发展给个人隐私权带来的一系列冲突问题，然后讨论了网络环境下对隐私权的保护措施和对策。     

The Effect of Transportation and Housing Subsidies on Urban Sprawl

This paper analyses theoretically the effect of transportation and housing subsidies on urban sprawl,modal choice decisions and urban spatial structure using a spatial general equilibrium model in a monocentric city with two transport modes. Our analysis shows that public transit subsidy leads to urban shrink,whilst subsidizing automobile and housing make the city sprawl. We also find the effects of the other factors on urban sprawl,such as households income and demand,rural land rent,the income tax rate,the total fixed cost of public transit and automobile and the travelling marginal cost of public transit and automobile. Furthermore,this paper also studies how to maximize the urban-area-wide spatial equilibrium utility level.     

Minimum information about a microarray experiment (MIAME)-toward standards for microarray data.

Microarray analysis has become a widely used tool for the generation of gene expression data on a genomic scale. Although many significant results have been derived from microarray studies, one limitation has been the lack of standards for presenting and exchanging such data. Here we present a proposal, the Minimum Information About a Microarray Experiment (MIAME), that describes the minimum information required to ensure that microarray data can be easily interpreted and that results derived from its analysis can be independently verified. The ultimate goal of this work is to establish a standard for recording and reporting microarray-based gene expression data, which will in turn facilitate the establishment of databases and public repositories and enable the development of data analysis tools. With respect to MIAME, we concentrate on defining the content and structure of the necessary information rather than the technical format for capturing it.     

布朗运动关于某些集首中点的分布

本文根据1-维布朗运动的一些熟知结果,由高维布朗运动各分量间的独立性出发,解决了关于长方柱面、长方体表面、一对平行超平面所界带域、第一卦限、由某些正半坐标平面所围成的角域之边界等集合的首中点分布问题,然后利用布朗运动与Dirichlet-问题的联系,解决了以上集合内D-问题的求解问题。     

基于协处理器的无线传感器网络MAC设计

提出了一种基于协处理器的媒介访问控制(MAC)体系结构.将不同MAC协议的信道争用机制映射为协处理器内部的软件程序.其特点是兼容IEEE802.15.4协议,利用可编程协处理器增强MAC的可重用性,能支持自适应睡眠媒介访问挖制(S-MAC)、超时媒介访问控制(T-MAC)等无线传感器网络MAC协议.阐述了基于协处理器实现避免冲突的载波侦听多路访问(CSMA-CA)算法、S-MAC和T-MAC协议的方法.并在此基础上分析了CSMA-CA算法的软件时延.在现场可编程门阵列(FPGA)上实现整个MAC,实际测试结果表明:该MAC支持多协议,数据传输速率达20～250 Kbit/s,适应IEEE802.15.4协议要求.面积仅为30 567个等效门.     

Systematic pathway analysis using high-resolution fitness profiling of combinatorial gene deletions

Systematic genetic interaction studies have illuminated many cellular processes. Here we quantitatively examine genetic interactions among 26 Saccharomyces cerevisiae genes conferring resistance to the DNA-damaging agent methyl methanesulfonate (MMS), as determined by chemogenomic fitness profiling of pooled deletion strains. We constructed 650 double-deletion strains, corresponding to all pairings of these 26 deletions. The fitness of single- and double-deletion strains were measured in the presence and absence of MMS. Genetic interactions were defined by combining principles from both statistical and classical genetics. The resulting network predicts that the Mph1 helicase has a role in resolving homologous recombination-derived DNA intermediates that is similar to (but distinct from) that of the Sgs1 helicase. Our results emphasize the utility of small molecules and multifactorial deletion mutants in uncovering functional relationships and pathway order.