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121.
Summary Resting oxygen consumption of the vascularly isolated gracilis anticus muscle of the rat perfused by natural circulation via the femoral artery with diluted or undiluted blood depends on oxygen delivery (the product of flow rate and arterial oxygen concentration-DO2) only when DO2 falls below 16 l/min/g. 相似文献
122.
F. V. DeFeudis L. M. Orensanz Muñoz M. A. Vidal G. Corrochano M. Sanchez del Alamo 《Cellular and molecular life sciences : CMLS》1978,34(9):1169-1170
Summary High-affinity, Na+-independent binding of -alanine to a synaptosomal fraction of rat brain was potently inhibited by glycine and by some other -amino acids, but not by taurine or GABA. This binding mechanism, which was also sensitive to both bicuculline and strychnine, might involve synaptic receptors for both -alanine and glycine.This study was supported in part by Centro Ramón y Cajal and Fundacion Juan March. 相似文献
123.
T. T. Yen J. A. Allan D. V. Pearson J. M. Acton 《Cellular and molecular life sciences : CMLS》1978,34(12):1542-1543
Summary Treating VY/WfL-A
vy
/a mice with 5-androstan-17-one, a mammalian glucose-6-phosphate dehydrogenase inhibitor, prevented the mice from becoming obese. The weight difference between treated and controlA
vy
/a mice was mainly due to a decreased accumulation of triacylglycerol. The compound did not suppress appetite, had no detectable toxicity and did not affect the lipogenesis rates in the liver and carcass. The weight-controlling effect of 5-androstan-17-one inA
vy
/a mice was reversible upon withdrawal of treatment.The authors wish to thank Mr W.R. Gibson and Drs C.G. Culbertson and P.N. Harris for performing the pathological examinations. 相似文献
124.
Summary The secondary disease in PF1 strain combination depends upon the immune status of both partners. It is most clearly expressed if both donors and recipients are immunologically crippled by thymectomy and irradiation. Conspicuous reduction in the immune potential of parental parabionts induced by thymectomy and irradiation displayed their marked incidence of parabiotic death. 相似文献
125.
M. Schwab J. Haas S. Abdo M. R. Ahuja G. Kollinger A. Anders F. Anders 《Cellular and molecular life sciences : CMLS》1978,34(6):780-782
Summary Specific genotypes of the xiphophorine fish develop neoplasms following treatment with N-methyl-N-nitrosourea or X-rays. Several of these neoplasms can be related to the presence of specific chromosomes. The implications of these findings are discussed.Supported by Deutsche Forschungsgemeinschaft through Sonderforschungsbereich 103 Zellenergetik und Zelldifferenzierung, Marburg (projects C 9 and C 10), and by Justus-Liebig-Universität Giessen. We are indebted to Prof. K. Frese, Veterinär-Pathologisches Institut, Giessen and Dr H. D. Mennel, Pathologisches Institut, Freiburg, for their help in the classification of neoplasms. We furthermore thank K. Klinke for breeding the fish. Dedicated to Prof. C. Kosswig on the occasion of his 75th birthday.The paper contains parts of the dissertations of S. Abdo, J. Haas and G. Kollinger.supported by the Egypt ministry of education. 相似文献
126.
M. Tardy B. Rolland J. Bardakdjian P. Gonnard 《Cellular and molecular life sciences : CMLS》1978,34(9):1137-1138
Summary -(4-chlorophenyl)-GABA, a GABA mimetic compound, acts as an inhibitor of GABA metabolism in both synaptosomal and extrasynaptosomal compartments. It has no significant action on GABA or Glu uptake by synaptosomes. 相似文献
127.
N. Michajlovskij V. Štrbák O. Földes 《Cellular and molecular life sciences : CMLS》1978,34(3):409-410
Summary The administration of thiocyanate to rats caused a significant increase of serum free thyroxine fraction, which coincided with the significant decrease of TSH level. The other components (AFT4, T4, T3) in serum at this time were decreased or unchanged. The finding suggests the role of free thyroxine fraction in feed-back regulation of TSH secretion.Acknowledgment. We thank Dr A. Parlow and the NIAMDD, Rat Pituitary Hormone Distribution Program, for material for rat TSH immunoassay; Dr J. Nauman (Inst. Postgrad. Med., Warsaw, Poland) for T3 antibody, and to Ing. J. Sadlo, Mrs M. t'astná and Miss R Fajkoová for technical assistance. 相似文献
128.
Summary Pentobarbital concentrations of 10–100 M selectively inhibited the noradrenaline release evoked by activation of the nicotinic receptors on the terminals sympathetic nerves of the rabbit heart. Higher concentrations also decreased the noradrenaline release induced by KCl or by electrical stimulation of the nerve axons.This paper is dedicated to Professor Dr. G. Malorny on the occasion of his 65th birthday.Acknowledgment: We thank Mrs G. Thielecke for technical assistance. 相似文献
129.
Summary The seedling growth ofBrassica campestris var.varuna, has been studied, as affected by water-stress and gibberellin treatments. A boost in the net GA response due to water-stress, has been observed. Thus presence of GA can overcome the water-stress effects.Publication No. 26 from Dept of Biosciences, Himachal Pradesh University, Simla. Authors are grateful to CSIR, New Delhi, for JRF to SB. 相似文献
130.
Summary The effects of L-glutamic acid and of some glutamate analogues have been studied on the central nervous system of the snailHeobania vermiculata, using conventional electrophysiological techniques. The glutamate H-response had the mean equilibrium value of-(57±4) mV and was associated with a Cl– conductance change. The D-response to glutamate application showed an involvement of sodium ions. Aspartate was agonist of glutamate action and displayed similar equilibrium value of the H-response, whereas quisqualate H-response was non-invertible.The authors wish to express their thanks to Prof. A. Curatolo for his continual interest and advice, and to Dr J. Stinnakre for the criticism of the text. 相似文献