Genetic control by the HLA region of the immune response to factor VIII in hemophilic patients]

In 10 sibships of haemophilic A patients, every one including 1 haemophilic brother with an antibody to factor VIII and 1 haemophilic brother without antibody, pattern of HLA segregation was analysed. All sibships were HLA haploidentical or different and not HLA identical. This fact suggested a linkage between the major histocompatibility complex and an "Ir" gene to factor VIII.     

Effect of insulin on immunological phagocytosis by macrophages.

It was shown that, in physiological concentrations, insulin enhances, in vitro, the immunological phagocytosis of sensitized sheep erythrocytes by cultured mouse peritoneal macrophages. Insulin seems to stimulate macrophage phagocytosis as a cholinomimetic agonist by increasing the intracellular levels of cyclic GMP.     

Structure specificity of some immunoadjuvant synthetic glycopeptides

Summary The immunoadjuvant activity of muramyl dipeptide seems to be critically dependent on the type of substitution of the -carboxyl group of the D-isoglutamine residue. Moreover the nonapeptide L-Ala-D-isoGlu-L-Lys-D-Ala-(Gly)₅-OME also shows a definite effect.     

Pyrogen fever in rabbits pretreated with p-chlorophenylalanine or 5, 6-dihydroxytryptamine.

The hyperthermic effect of a bacterial pyrogen has been studied in rabbits pretreated or not with p-chlorophenylalanine or 5, 6-dihydroxytryptamine. The results obtained indicate that a selective reduction of cerebral 5-hydroxytryptamine levels by these drugs do not significantly affect pyrogen hypertermia.     

基于自适应直线拟合的角点检测

角点检测是计算机视觉的一个基本问题，进行角点检测的关键是估算曲率。笔者给出了一种新的基于参考点的前后曲线方向估计的曲率计算方法。我们以离散点远离直线垂直距离误差最小为目标进行直线拟合，同时根据误差大小来自适应的选择拟合窗口的大小。很好地解决了角点曲率计算时拟合窗口大小和计算精度间的矛盾，实验证明，该方法抗干扰性好，且运算量不大，对于存在明显转折点的曲线角点有很好的检测和定位能力。     

D类音频功率放大器控制方式综述

D类放大器虽然具有很高的效率，但由于功率晶体管的开关工作方式，D类放大器引入的失真通常大于线性放大器，这也是目前D类放大器在音频放大领域并未得到广泛应用的主要原因。D类放大器的控制方式是影响其性能的关键因素之一，研究适合的控制方法以改善D类放大器的保真度，是近年来电力电子技术和音频功放放大领域研究的热点。文中对几种比较新颖的D类音频功放放大器控制方式进行了分析比较。     

渠道管理中的厂商与分销商的博弈分析

分销渠道管理中生产厂商与分销商的良好合作是进行优势互补、提高渠道竞争力和适应市场变化的有效手段。通过对生产厂商与分销商合作交易特征介绍和交易条件的假设，基于相互之间合作的关系建立混合博弈模型，并进行分析，找出影响双方合作关系的因素和实行稳定作的条件；然后，进一步对生产厂商与分销商的长期合作进行有限次重复博弈分析，找出影响双方合作关系的条件，最后，根据推论分析的结果，指出生产厂商与分销商建立良好的合作关系应采用的策略。     

体育教学中实施素质教育途径的初探

根据素质教育的基本特征和学校体育教学的目的任务 ,本文分析了在体育教学中实施素质教育的必要性和高层次性 ,指出了体育教学中存在的与素质教育不相适应的诸多弊端 ,以及如何进行体育教学改革的基本思想和对策