Development of Cueing Algorithm Based on “Closed-Loop” Control for Flight Simulator Motion System

The classical washout algorithm had fixed gains and manually constructed filters, so that it led to poor adaptability. Furthermore, it lost the sustained acceleration cues of high-and mid-frequency in cross-over(tilt-coordination) channel, and the acceleration of cross-over frequency was also limited by angular velocity limiter, so the false cues in flight simulation process were clearly perceived by pilots. The paper studied the characteristics of the classical washout algorithm and flight simulator motion platform, tried to redesign the source of cross-over acceleration channel and translation acceleration channel, and transferred the part of cross-over acceleration that was unsimulated sustained acceleration to translation acceleration channel. Comparisons were mainly made between classical washout algorithm and revised algorithm in a longitudinal/pitch direction. The evaluation was based on the implementation of human vestibular perception system. The results demonstrated that the revised algorithm could significantly reduce the phase lag, and improved the spikes tracking performance. Furthermore, sensory angular velocity and the error of sensory acceleration were strictly controlled within the threshold of human perception system, and the displacement was a little broader than the classical washout algorithm. Therefore, it was proved that the new algorithm could diminish the filters parameters and heighten the self-adaptability for the washout algorithm. In addition, the magnitude of false cues was remarkably reduced during flight simulator, and the workspace utilization of the motion platform was developed by "closed-loop" control system.     

Structure of Dnmt3a bound to Dnmt3L suggests a model for de novo DNA methylation

Genetic imprinting, found in flowering plants and placental mammals, uses DNA methylation to yield gene expression that is dependent on the parent of origin. DNA methyltransferase 3a (Dnmt3a) and its regulatory factor, DNA methyltransferase 3-like protein (Dnmt3L), are both required for the de novo DNA methylation of imprinted genes in mammalian germ cells. Dnmt3L interacts specifically with unmethylated lysine 4 of histone H3 through its amino-terminal PHD (plant homeodomain)-like domain. Here we show, with the use of crystallography, that the carboxy-terminal domain of human Dnmt3L interacts with the catalytic domain of Dnmt3a, demonstrating that Dnmt3L has dual functions of binding the unmethylated histone tail and activating DNA methyltransferase. The complexed C-terminal domains of Dnmt3a and Dnmt3L showed further dimerization through Dnmt3a-Dnmt3a interaction, forming a tetrameric complex with two active sites. Substitution of key non-catalytic residues at the Dnmt3a-Dnmt3L interface or the Dnmt3a-Dnmt3a interface eliminated enzymatic activity. Molecular modelling of a DNA-Dnmt3a dimer indicated that the two active sites are separated by about one DNA helical turn. The C-terminal domain of Dnmt3a oligomerizes on DNA to form a nucleoprotein filament. A periodicity in the activity of Dnmt3a on long DNA revealed a correlation of methylated CpG sites at distances of eight to ten base pairs, indicating that oligomerization leads Dnmt3a to methylate DNA in a periodic pattern. A similar periodicity is observed for the frequency of CpG sites in the differentially methylated regions of 12 maternally imprinted mouse genes. These results suggest a basis for the recognition and methylation of differentially methylated regions in imprinted genes, involving the detection of both nucleosome modification and CpG spacing.     

Modulation of Saturn's radio clock by solar wind speed

The internal rotation rates of the giant planets can be estimated by cloud motions, but such an approach is not very precise because absolute wind speeds are not known a priori and depend on latitude: periodicities in the radio emissions, thought to be tied to the internal planetary magnetic field, are used instead. Saturn, despite an apparently axisymmetric magnetic field, emits kilometre-wavelength (radio) photons from auroral sources. This emission is modulated at a period initially identified as 10 h 39 min 24 +/- 7 s, and this has been adopted as Saturn's rotation period. Subsequent observations, however, revealed that this period varies by +/-6 min on a timescale of several months to years. Here we report that the kilometric radiation period varies systematically by +/-1% with a characteristic timescale of 20-30 days. Here we show that these fluctuations are correlated with solar wind speed at Saturn, meaning that Saturn's radio clock is controlled, at least in part, by conditions external to the planet's magnetosphere. No correlation is found with the solar wind density, dynamic pressure or magnetic field; the solar wind speed therefore has a special function. We also show that the long-term fluctuations are simply an average of the short-term ones, and therefore the long-term variations are probably also driven by changes in the solar wind.     

Transformation of spin information into large electrical signals using carbon nanotubes

Spin electronics (spintronics) exploits the magnetic nature of electrons, and this principle is commercially applied in, for example, the spin valves of disk-drive read heads. There is currently widespread interest in developing new types of spintronic devices based on industrially relevant semiconductors, in which a spin-polarized current flows through a lateral channel between a spin-polarized source and drain. However, the transformation of spin information into large electrical signals is limited by spin relaxation, so that the magnetoresistive signals are below 1% (ref. 2). Here we report large magnetoresistance effects (61% at 5 K), which correspond to large output signals (65 mV), in devices where the non-magnetic channel is a multiwall carbon nanotube that spans a 1.5 microm gap between epitaxial electrodes of the highly spin polarized manganite La(0.7)Sr(0.3)MnO3. This spintronic system combines a number of favourable properties that enable this performance; the long spin lifetime in nanotubes due to the small spin-orbit coupling of carbon; the high Fermi velocity in nanotubes that limits the carrier dwell time; the high spin polarization in the manganite electrodes, which remains high right up to the manganite-nanotube interface; and the resistance of the interfacial barrier for spin injection. We support these conclusions regarding the interface using density functional theory calculations. The success of our experiments with such chemically and geometrically different materials should inspire new avenues in materials selection for future spintronics applications.     

楚-萨雷苏盆地考可潘索尔坳陷天然气含氮特征及其成因

通过天然气组分统计分析,结合区域构造演化、烃源岩成熟度历史、典型气藏解剖分析,确定考克潘索尔坳陷氮气的空间分布特征及其主控因素,包括有机质热演化程度、天然气运聚过程、基岩地层的高放射性等。研究表明:天然气组分中氮气含量在垂向上表现为下石炭统低、上泥盆统较高、二叠系最高的分布特点;泥盆系烃源岩大部分已经处于过成熟阶段,因此生成了富氮的天然气,在埋深较大的圈闭中,勘探的经济风险增加;二叠系气藏为典型的下生上储,靠断裂沟通下部烃源岩,天然气的高含氮也与高成熟天然气的垂向运聚密切相关,其总体勘探潜力不大。     

Robust ranking of multi criteria alternatives using value functions compatible with holistic preference information

We present two recent methods, called UTAGMS and GRIP, from the viewpoint of robust ranking of multicriteria alternatives. In these methods, the preference information provided by a single or multiple Decision Makers (DMs) is composed of holistic judgements of some selected alternatives, called reference alternatives. The judgements express pairwise comparisons of some reference alternatives (in UTAGMS), and comparisons of selected pairs of reference alternatives from the viewpoint of intensity of preference (in GRIP). Ordinal regression is used to find additive value functions compatible with this preference information. The whole set of compatible value functions is then used in Linear Programming (LP) to calculate a necessary and possible weak preference relations in the set of all alternatives, and in the set of all pairs of alternatives. While the necessary relation is true for all compatible value functions, the possible relation is true for at least one compatible value function. The necessary relation is a partial preorder and the possible relation is a complete and negatively transitive relation. The necessary relations show consequences of the given preference information which are robust because “always true”. We illustrate this methodology with an example.     

三线圈磁场均匀性的分析

通过改装亥姆霍兹线圈成平行共轴三线圈获得均匀性更好的磁场,利用Mathematica软件推导出平行共轴三线圈磁场均匀性最好的条件,分析了其中心区域磁场的均匀度,并绘出几种不同区域所对应的磁场Bx（x,y）和By（x,y）的立体图．     

半刚接钢框架系统强度可靠性对随机变量的敏感性分析

将梯度优化法与有限元法相结合,研究了结构失效模式可靠度对随机变量的敏感性,并用PNET法分析了结构系统强度可靠度对随机变量的敏感性.通过算例,分析刚接和半刚接钢框架系统强度可靠度对多个随机变量的敏感性,结果表明:结构系统强度可靠度对梁柱截面抗弯弯矩和部分荷载的均值和变异系数敏感性显著,对梁长和柱高的变异系数敏感性较小;半刚接结构的强度可靠度对半刚性连接极限弯矩的均值和变异系数较为敏感,特别当其变异系数较大时,结构的系统可靠度对其取值尤为敏感.