全文获取类型
收费全文 | 184篇 |
免费 | 0篇 |
国内免费 | 2篇 |
专业分类
现状及发展 | 57篇 |
研究方法 | 38篇 |
综合类 | 91篇 |
出版年
2018年 | 1篇 |
2016年 | 1篇 |
2015年 | 2篇 |
2014年 | 2篇 |
2013年 | 1篇 |
2012年 | 15篇 |
2011年 | 9篇 |
2008年 | 9篇 |
2007年 | 6篇 |
2006年 | 9篇 |
2005年 | 6篇 |
2004年 | 6篇 |
2003年 | 10篇 |
2002年 | 4篇 |
2001年 | 5篇 |
2000年 | 4篇 |
1999年 | 4篇 |
1996年 | 2篇 |
1995年 | 1篇 |
1994年 | 1篇 |
1993年 | 1篇 |
1992年 | 1篇 |
1991年 | 2篇 |
1990年 | 3篇 |
1989年 | 2篇 |
1988年 | 3篇 |
1987年 | 8篇 |
1986年 | 9篇 |
1985年 | 9篇 |
1984年 | 3篇 |
1983年 | 4篇 |
1982年 | 4篇 |
1981年 | 5篇 |
1980年 | 4篇 |
1979年 | 2篇 |
1978年 | 1篇 |
1977年 | 2篇 |
1976年 | 1篇 |
1975年 | 2篇 |
1974年 | 2篇 |
1973年 | 1篇 |
1972年 | 1篇 |
1971年 | 3篇 |
1970年 | 2篇 |
1969年 | 4篇 |
1968年 | 2篇 |
1967年 | 1篇 |
1966年 | 3篇 |
1965年 | 2篇 |
1963年 | 1篇 |
排序方式: 共有186条查询结果,搜索用时 15 毫秒
81.
K. Takahashi I. Kaneko M. Date E. Fukada 《Cellular and molecular life sciences : CMLS》1986,42(2):185-186
Summary DNA synthesis in Chinese hamster V79 cells was significantly enhanced when they were exposed to weak, pulsing electromagnetic fields generated by specific combinations of the pulse width (25s), frequency (10, 100 Hz) and magnetic intensity (2×10–5 8×10–5T). Conversely the DNA synthesis of cells in the fields at 4×10–4 T was repressed to 80% of that in controls not exposed to the fields.This work was supported by Kaken Pharmaceutical Co., Ltd, Tokyo, Japan, and in part by a Grant-in-Aid from the Ministry of Education, Science and Culture of Japan and from the Foundation for Life Science Promotion Tokyo, Japan to I.K. 相似文献
82.
研究了含2%W和V的Fe-Cr-Mn合金经热时效处理和电子辐照条件下,溶质元素晶界偏聚和析出相的行为。实验结果表明:在含W、V合金中热时效引起Cr、Mn晶界贫化,它决定于富Cr碳化物M_(23)C_6中组元组成。辐照条件下,两种合金中Cr、Mn都发生晶界贫化,它决定于辐照产生空位浓度和空洞体胀量,辐照诱起晶界元素偏聚影响析出相成分。 相似文献
83.
Dioxin receptor is a ligand-dependent E3 ubiquitin ligase 总被引:2,自引:0,他引:2
Ohtake F Baba A Takada I Okada M Iwasaki K Miki H Takahashi S Kouzmenko A Nohara K Chiba T Fujii-Kuriyama Y Kato S 《Nature》2007,446(7135):562-566
84.
Embryonic stem (ES) cells are pluripotent cells derived from early mammalian embryos. Their immortality and rapid growth make them attractive sources for stem cell therapies; however, they produce tumours (teratomas) when transplanted, which could preclude their therapeutic usage. Why ES cells, which lack chromosomal abnormalities, possess tumour-like properties is largely unknown. Here we show that mouse ES cells specifically express a Ras-like gene, which we have named ERas. We show that human HRasp, which is a recognized pseudogene, does not contain reported base substitutions and instead encodes the human orthologue of ERas. This protein contains amino-acid residues identical to those present in active mutants of Ras and causes oncogenic transformation in NIH 3T3 cells. ERas interacts with phosphatidylinositol-3-OH kinase but not with Raf. ERas-null ES cells maintain pluripotency but show significantly reduced growth and tumorigenicity, which are rescued by expression of ERas complementary DNA or by activated phosphatidylinositol-3-OH kinase. We conclude that the transforming oncogene ERas is important in the tumour-like growth properties of ES cells. 相似文献
85.
1 Results Low-temperature synthetic techniques called “chimie douce“ have resulted in major developments in the field of solid state chemistry of transition metal oxides. The systematic study of oxide bronzes in the period 1950-1980 paved the way to further advances in the solid state chemistry of oxides, including the alkali metal intercalation(deintercalation chemistry by soft chemical and/or electrochemical methods. These techniques also gave access to new metastable compounds such as several new f... 相似文献
86.
T Aoyagi T Wada M Nagai F Kojima S Harada T Takeuchi H Takahashi K Hirokawa T Tsumita 《Experientia》1990,46(1):94-97
We examined the changes in the intracerebral activities, at the time of postmortem autopsy, in patients with Alzheimer's disease. When compared with the control group, the activity of kallikrein-like enzyme was significantly decreased, while prolyl endopeptidase activity increased, in the patients group. Aprotinin inhibited 50% of the activity of the former enzyme at 2 x 10(-7) M. Taken together with the results of a multivariate study, the above findings may indicate that intracerebral kallikrein deficiency plays an important role in the pathogenesis of Alzheimer's disease. 相似文献
87.
H. Numata A. Numata C. Takahashi Y. Nakagawa K. Iwatani S. Takahashi K. Miura Y. Chinzei 《Cellular and molecular life sciences : CMLS》1992,48(6):606-610
Juvenile hormone I (JH I) was identified by combined gas chromatography/mass spectrometry as the predominant JH in the hemolymph of female adults of the bean bug,Riptortus clavatus (Thunberg) (Hemiptera: Alydidae). Among JH I, II, and III, JH I was the most effective hormone for inducing the synthesis of yolk proteins in diapause adults. 相似文献
88.
I Nagatsu M Ito Y Kawakami N Karasawa H Takahashi K Fujita T Nagatsu 《Experientia》1985,41(8):1054-1055
The amount of tyrosine hydroxylase protein in the adrenal medulla, which was estimated by a quantitative immunofluorescence method, was higher in spontaneously hypertensive rats than in normotensive control Wistar-Kyoto rats at 4 and 16 weeks of age before and after the development of hypertension. 相似文献
89.
Effect of pulsing electromagnetic fields on DNA synthesis in mammalian cells in culture 总被引:3,自引:0,他引:3
DNA synthesis in Chinese hamster V79 cells was significantly enhanced when they were exposed to weak, pulsing electromagnetic fields generated by specific combinations of the pulse width (25 microseconds), frequency (10, 100 Hz) and magnetic intensity (2 X 10(-5), 8 X 10(-5) T). Conversely the DNA synthesis of cells in the fields at 4 X 10(-4) T was repressed to 80% of that in controls not exposed to the fields. 相似文献
90.
K. Takahashi T. Akagi Y. Ohtsuki H. Sonobe H. Yamaguchi 《Cellular and molecular life sciences : CMLS》1982,38(11):1349-1351
The immunohistochemical distribution of histiocytes containing S-100 protein-like antigen in the skin lesions of cutaneous T-cell lymphoma/leukemia is investigated. Marked hyperplasia of these histiocytes is found in two cases of mycosis fungoides.We thank Prof. Y. Ishida, Gunma University School of Medicine, Dr K. Iwata, Kochi Prefectural Central Hospital, Dr M. Motoi, Okayama University Medical School, Dr H. Enzan, Kochi Medical School, for supplying the material. 相似文献