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11.
从1995年开始实行的韩国质量革新计划(SinglePPM)运动是为了提高从合作企业纳入的产品质量。此项运动的目标是将包括成品不合格率和区域索赔的交货不合格率减少至10ppm以内或100ppm以下。至今,从韩国政府获得S-PPM认证的企业有1053家。这项质量革新计划不单纯是为提高产品质量,而且也为提高企业的信誉度做贡献。 相似文献
12.
CAOJunji WANGYaqiang ZHANGXiaoye Leeshuncheng HoKinfai CAOYunning LIYang 《科学通报(英文版)》2004,49(15):1637-1641
Methods were developed to determine the mass ratios of carbon isotopes in trace amounts of aerosol carbonate. A Finnigan MAT 252 mass spectrometer fitted with an on-line Kiel device was to determine the ^13C/^12C ratio in CO2 produced from the carbonate. A study using these methods was conducted to characterize the carbonate carbon isotopes in aerosol samples collected in Xi‘an on dusty and normal days during March and April 2002. Results of the study demonstrate that insights into the origin of the dust can be deduced from its isotopic composition. That is, the δ^13C ofcarbonate for dust storm samples ranged from -1.4‰ to -4.2‰, and this is consistent with sandy materials in dust source regions upwind. In contrast, for non-dusty days δ^13C ranged from -7.5% to -9.3‰, which is more similar to fine particles emitted from local surface soils. Comparisons of dust storm aerosols with surface soils from source regions and with aerosol samples collected downwind indicate that the δ^13C values did not change appreciably during longrange transport. Therefore, carbon isotopes have the potential for distinguishing among source materials, and this approach provides a powerful new tool for identifying dust provenance. 相似文献
13.
Books and archives experience aging which is affected by a variety of factors, such as microorganism, humidity, light and components of paper [1]. Thus, the studies concerning impacts of those factors on paper aging are required. In this paper, an accelerated paper aging was carried out to investigate the effects of acid and metals such as alum, copper ( Ⅱ ) sulfate, copper ( Ⅱ ) chloride, and iron (Ⅲ) chloride on paper aging. It was found that both acid and metals had impacts on paper aging. In particular, paper aging was far more accelerated in case that acid and metals were present in paper at the same time. 相似文献
14.
Aloysius Domingo David Amar Karen Grütz Lillian V. Lee Raymond Rosales Norbert Brüggemann Roland Dominic Jamora Eva Cutiongco-dela Paz Arndt Rolfs Dirk Dressler Uwe Walter Dimitri Krainc Katja Lohmann Ron Shamir Christine Klein Ana Westenberger 《Cellular and molecular life sciences : CMLS》2016,73(16):3205-3215
15.
Rakesh K. Sahoo Arya Das Saurabh Singh Damin Lee Saroj K. Singh Rajaram S. Mane Je Moon Yun Kwang Ho Kim 《自然科学进展(英文版)》2019,29(4):410-415
A 3D porous carbon-manganese oxide ([email protected]) nanocomposite is successfully synthesized via a thermal plasma deposition method. The chemical bonds and compositions, phase structures, surface morphologies, etc. of as-obtained [email protected] nanocomposite were characterized by the various equipment, such as X-ray diffractometer, X-ray photoelectron spectroscopy, and electron microscopes. The electrochemical performances of the [email protected] nanocomposite electrode showed a specific capacitance of 780 F g?1 at a current density of 2 A g?1 and a capacitance retention rate of 99% after 5000 charge-discharge cycles at a high current density of 10 A g?1. These excellent capacitive performances may be attributed to the encapsulation of MnO nanoparticles by porous carbon sheets in the [email protected] MnO nanocomposite structure. It is believed that the carbon-encapsulated MnO nanoparticles can be protected from a volume deformation during the charge adsorption/desorption cycle and can be electrically improved by the encapsulated carbon sheets, resulting in better overall capacitive performance. In addition, this study also demonstrates the practical applicability by assembling a supercapacitor using the as-obtained [email protected] nanocomposite to glow a light emitting diode. 相似文献
16.
Jinwon Lim Hyo-Jung Lee Bonglee Kim Jeong-Un Choi Yoeok Shin Eun Jung Sohn Sung-Hoon Kim 《科学通报(英文版)》2014,59(25):3127-3133
Though Hongbaekjeong(HBJ),a hebal mixture of three medicinal plants,has been traditionally used for arthritis and muscular pain,its scientific evidence still remains unclear.Thus,in the present study,analgesic and anti-inflammatory mechanism of HBJ was evaluated in vitro and in vivo.HBJ significantly reduced NO production and prostaglandin E2(PGE2)release and also attenuated the expression of cyclooxygenase 2(COX-2)in lipopolysaccharides(LPS)and interferon(IFN)-c treated RAW 264.7 cells.Furthermore,HBJ abrogated the production of proinflammatory cytokines such as interleukin(IL)1b,IL-6,IL-8 and monocyte chemoattractant protein-1(MCP-1)in LPS and IFN-c treated RAW 264.7 cells.In addition,HBJ significantly decreased the number of writhing syndrome induced by acetic acid,and also increased latency in hot-plate method and tail flick test in mice.Consistently,HBJ significantly reduced the edema volume in the hind paw of the rats with arthritis induced by Freund’s complete adjuvant(FCA)compared to untreated control.Collectively,our findings demonstrate the antiinflammatory and analgesic potential of HBJ via inhibition of proinflammatory cytokines and PGE2 release for treatment of arthritis and muscular pain. 相似文献
17.
Observing that a sequence of negative logarithms of 1‐year survival probabilities displays a linear relationship with the sequence of corresponding terms with a time lag of a certain number of years, we propose a simple linear regression to model and forecast mortality rates. Our model assuming the linearity between two mortality sequences with a time lag each other does not need to formulate the time trends of mortality rates across ages for mortality prediction. Moreover, the parameters of our model for a given age depend on the mortality rates for that age only. Therefore, whether the span of the study ages with the age included is widened or shortened will not affect the results of mortality fitting and forecasting for that age. In the empirical testing, the regression results using the mortality data for the UK, USA and Japan show a satisfactory goodness of fit, which convinces us of the appropriateness of the linear assumption. Empirical illustrations further show that our model's performances of fitting and forecasting mortality rates are quite satisfactory compared with the existing well‐known mortality models. Copyright © 2015 John Wiley & Sons, Ltd. 相似文献
18.
Giovanni Barone‐Adesi Marinela Adriana Finta Chiara Legnazzi Carlo Sala 《Journal of forecasting》2019,38(6):552-563
Using option market data we derive naturally forward‐looking, nonparametric and model‐free risk estimates, three desired characteristics hardly obtainable using historical returns. The option‐implied measures are only based on the first derivative of the option price with respect to the strike price, bypassing the difficult task of estimating the tail of the return distribution. We estimate and backtest the 1%, 2.5%, and 5% WTI crude oil futures option‐implied value at risk and conditional value at risk for the turbulent years 2011–2016 and for both tails of the distribution. Compared with risk estimations based on the filtered historical simulation methodology, our results show that the option‐implied risk metrics are valid alternatives to the statistically based historical models. 相似文献
19.
Chromosome integrity in response to chemically or radiation-induced chromosome breaks and the perturbation of ongoing replication
forks relies on multiple DNA repair mechanisms. However, repair of these lesions may lead to unwanted chromosome rearrangement
if not properly executed or regulated. As these types of chromosomal alterations threaten the cell’s and the organism’s very
own survival, multiple systems are developed to avoid or at least limit break-induced chromosomal rearrangements. In this
review, we highlight cellular strategies for repressing DNA break-induced chromosomal translocations in multiple model systems
including yeast, mouse, and human. These pathways select proper homologous templates or broken DNA ends for the faithful repair
of DNA breaks to avoid undesirable chromosomal translocations. 相似文献
20.
Parton LE Ye CP Coppari R Enriori PJ Choi B Zhang CY Xu C Vianna CR Balthasar N Lee CE Elmquist JK Cowley MA Lowell BB 《Nature》2007,449(7159):228-232
A subset of neurons in the brain, known as 'glucose-excited' neurons, depolarize and increase their firing rate in response to increases in extracellular glucose. Similar to insulin secretion by pancreatic beta-cells, glucose excitation of neurons is driven by ATP-mediated closure of ATP-sensitive potassium (K(ATP)) channels. Although beta-cell-like glucose sensing in neurons is well established, its physiological relevance and contribution to disease states such as type 2 diabetes remain unknown. To address these issues, we disrupted glucose sensing in glucose-excited pro-opiomelanocortin (POMC) neurons via transgenic expression of a mutant Kir6.2 subunit (encoded by the Kcnj11 gene) that prevents ATP-mediated closure of K(ATP) channels. Here we show that this genetic manipulation impaired the whole-body response to a systemic glucose load, demonstrating a role for glucose sensing by POMC neurons in the overall physiological control of blood glucose. We also found that glucose sensing by POMC neurons became defective in obese mice on a high-fat diet, suggesting that loss of glucose sensing by neurons has a role in the development of type 2 diabetes. The mechanism for obesity-induced loss of glucose sensing in POMC neurons involves uncoupling protein 2 (UCP2), a mitochondrial protein that impairs glucose-stimulated ATP production. UCP2 negatively regulates glucose sensing in POMC neurons. We found that genetic deletion of Ucp2 prevents obesity-induced loss of glucose sensing, and that acute pharmacological inhibition of UCP2 reverses loss of glucose sensing. We conclude that obesity-induced, UCP2-mediated loss of glucose sensing in glucose-excited neurons might have a pathogenic role in the development of type 2 diabetes. 相似文献