Dosis-Wirkungs-Beziehungen zwischen Koronardurchfluss und Herzfrequenz für Adenosin

Summary In the isolated guinea-pig heart, it has been found that the amount of adenosine which slows the heart rate is about 100 times greater than the amount which increases coronary flow.     

Shwartzman phenomenon without endotoxin preparation

Zusammenfassung Kasein, Pepton bzw. Baktokasiton wurde als präparierende Erstinjektion für lokalisiertes Shwartzman-Phänomen an Kaninchen verwendet. Nach provozierender i.v. Endotoxininjektion kommt es zum typischen Shwartzman-Phänomen. Da die verwendeten Substanzen Chemotaxis von Leukozyten verursachen, ist anzunehmen, dass die an Stelle der präparierenden Injektion angesammelten Leukozyten in der Ausbildung des Shwartzman-Phänomens eine vorwiegende Rolle spielen.     

Radiation induced avoidance behavior transfer by brain extracts of mice

Zusammenfassung In «naiven» Mäusen werden Verhaltensveränderungen nach Injektion kleiner Mengen von Gehirnmaterial aus Saccharin bevorzugenden und röntgenbestrahlten Mäusen beobachtet. Es trat Vermeidung der Saccharinlösung ein, und zwar ähnlich wie sonst in «trainierten», Saccharin bevorzugenden Tieren nach der Bestrahlung.     

Quantitative investigation on the possible losses of nucleic acids from ‘freeze-substituted’ tissue in the course of histological procedure

Résumé Les auteurs ont déterminé le contenu en acides nucléiques dans le foie du rat après la congélation-dessication dans du méthanol. Après cette technique, une grande partie de DNA était soluble dans l'eau.      

Dystrophic mutation (dy2J) affecting regulation of lactate dehydrogenase (LDH) and pyruvate kinase (PK) in C57BL/6J mice

Summary The genotype difference (dystrophic vs nondystrophic) in the LDH isozymes is observed in kidney. These differences are evident only at birth and at early developmental stages (before the expression of dystrophic symptoms). The tissue specific genotype differences for PK are limited to the thigh muscle (M form) and heart (L form), after the onset of the condition. These differences may reflect the pleiotropic effect of the dy^2J locus during the temporal regulation of these and other enzymes implicated in muscular dystrophy (MD).This research was financed by a Natural Sciences and Engineering Research Council Canada grant to S.M.S.     

Inhibition of neurotensin (NT)-induced glucagon release by [D-Trp11]-NT1

Summary A synthetic analog of neurotensin (NT), [D-Trp¹¹]-NT, antagonized NT-induced hyperglucagonemia and hyperglycemia, and also NT-induced glucagon release from pancreatic islets in rats.This work was supported in part by a grant from the Imanaga Medical Research Foundation, Nagoya, Japan. Address for reprint requests: M.U., Department of Surgery, National Nagoya Railway Hospital, Taiko 1-chome, Nakamura-ku, Nagoya 453, Japan.     

Effects of Ca2+ and Mg2+ on motility of sea urchin spermatozoa

Summary Swimming speed of sea urchin spermatozoa, measured by a light scattering technique, did not change with 0-20 mM Ca²⁺ in the medium. The speed was maximum at the normal concentration of Mg²⁺ (49 mM) in sea water.Supported by grants-in-aid from the Ministry of Education, Science and Culture, Japan, and a grant from the Ford Foundation.