排序方式: 共有126条查询结果,搜索用时 31 毫秒
111.
The worldwide leaf economics spectrum 总被引:48,自引:0,他引:48
Wright IJ Reich PB Westoby M Ackerly DD Baruch Z Bongers F Cavender-Bares J Chapin T Cornelissen JH Diemer M Flexas J Garnier E Groom PK Gulias J Hikosaka K Lamont BB Lee T Lee W Lusk C Midgley JJ Navas ML Niinemets U Oleksyn J Osada N Poorter H Poot P Prior L Pyankov VI Roumet C Thomas SC Tjoelker MG Veneklaas EJ Villar R 《Nature》2004,428(6985):821-827
Bringing together leaf trait data spanning 2,548 species and 175 sites we describe, for the first time at global scale, a universal spectrum of leaf economics consisting of key chemical, structural and physiological properties. The spectrum runs from quick to slow return on investments of nutrients and dry mass in leaves, and operates largely independently of growth form, plant functional type or biome. Categories along the spectrum would, in general, describe leaf economic variation at the global scale better than plant functional types, because functional types overlap substantially in their leaf traits. Overall, modulation of leaf traits and trait relationships by climate is surprisingly modest, although some striking and significant patterns can be seen. Reliable quantification of the leaf economics spectrum and its interaction with climate will prove valuable for modelling nutrient fluxes and vegetation boundaries under changing land-use and climate. 相似文献
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A common genetic risk factor for colorectal and prostate cancer 总被引:14,自引:0,他引:14
Haiman CA Le Marchand L Yamamato J Stram DO Sheng X Kolonel LN Wu AH Reich D Henderson BE 《Nature genetics》2007,39(8):954-956
Variants on chromosome 8q24 contribute risk for prostate cancer; here, we tested whether they also modulate risk for colorectal cancer. We studied 1,807 affected individuals and 5,511 controls and found that one variant, rs6983267, is also significantly associated with colorectal cancer (odds ratio = 1.22; P = 4.4 x 10(-6)) and that the apportionment of risk among the variants differs significantly between the two cancers. Comprehensive testing in the region uncovered variants capturing significant additional risk. Our results show that variants at 8q24 have different effects on cancer development that depend on the tissue type. 相似文献
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Principal components analysis corrects for stratification in genome-wide association studies 总被引:8,自引:0,他引:8
Population stratification--allele frequency differences between cases and controls due to systematic ancestry differences-can cause spurious associations in disease studies. We describe a method that enables explicit detection and correction of population stratification on a genome-wide scale. Our method uses principal components analysis to explicitly model ancestry differences between cases and controls. The resulting correction is specific to a candidate marker's variation in frequency across ancestral populations, minimizing spurious associations while maximizing power to detect true associations. Our simple, efficient approach can easily be applied to disease studies with hundreds of thousands of markers. 相似文献
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Martin F Aerts A Ahrén D Brun A Danchin EG Duchaussoy F Gibon J Kohler A Lindquist E Pereda V Salamov A Shapiro HJ Wuyts J Blaudez D Buée M Brokstein P Canbäck B Cohen D Courty PE Coutinho PM Delaruelle C Detter JC Deveau A DiFazio S Duplessis S Fraissinet-Tachet L Lucic E Frey-Klett P Fourrey C Feussner I Gay G Grimwood J Hoegger PJ Jain P Kilaru S Labbé J Lin YC Legué V Le Tacon F Marmeisse R Melayah D Montanini B Muratet M Nehls U Niculita-Hirzel H Oudot-Le Secq MP Peter M Quesneville H 《Nature》2008,452(7183):88-92
Mycorrhizal symbioses--the union of roots and soil fungi--are universal in terrestrial ecosystems and may have been fundamental to land colonization by plants. Boreal, temperate and montane forests all depend on ectomycorrhizae. Identification of the primary factors that regulate symbiotic development and metabolic activity will therefore open the door to understanding the role of ectomycorrhizae in plant development and physiology, allowing the full ecological significance of this symbiosis to be explored. Here we report the genome sequence of the ectomycorrhizal basidiomycete Laccaria bicolor (Fig. 1) and highlight gene sets involved in rhizosphere colonization and symbiosis. This 65-megabase genome assembly contains approximately 20,000 predicted protein-encoding genes and a very large number of transposons and repeated sequences. We detected unexpected genomic features, most notably a battery of effector-type small secreted proteins (SSPs) with unknown function, several of which are only expressed in symbiotic tissues. The most highly expressed SSP accumulates in the proliferating hyphae colonizing the host root. The ectomycorrhizae-specific SSPs probably have a decisive role in the establishment of the symbiosis. The unexpected observation that the genome of L. bicolor lacks carbohydrate-active enzymes involved in degradation of plant cell walls, but maintains the ability to degrade non-plant cell wall polysaccharides, reveals the dual saprotrophic and biotrophic lifestyle of the mycorrhizal fungus that enables it to grow within both soil and living plant roots. The predicted gene inventory of the L. bicolor genome, therefore, points to previously unknown mechanisms of symbiosis operating in biotrophic mycorrhizal fungi. The availability of this genome provides an unparalleled opportunity to develop a deeper understanding of the processes by which symbionts interact with plants within their ecosystem to perform vital functions in the carbon and nitrogen cycles that are fundamental to sustainable plant productivity. 相似文献