首页 | 本学科首页   官方微博 | 高级检索  
文章检索
  按 检索   检索词:      
出版年份:   被引次数:   他引次数: 提示:输入*表示无穷大
  收费全文   43061篇
  免费   133篇
  国内免费   151篇
系统科学   327篇
丛书文集   868篇
教育与普及   79篇
理论与方法论   142篇
现状及发展   19129篇
研究方法   1640篇
综合类   20407篇
自然研究   753篇
  2013年   299篇
  2012年   575篇
  2011年   1326篇
  2010年   240篇
  2008年   680篇
  2007年   819篇
  2006年   776篇
  2005年   810篇
  2004年   860篇
  2003年   763篇
  2002年   738篇
  2001年   1259篇
  2000年   1214篇
  1999年   791篇
  1992年   793篇
  1991年   624篇
  1990年   671篇
  1989年   614篇
  1988年   616篇
  1987年   643篇
  1986年   648篇
  1985年   876篇
  1984年   633篇
  1983年   530篇
  1982年   462篇
  1981年   498篇
  1980年   625篇
  1979年   1373篇
  1978年   1068篇
  1977年   1026篇
  1976年   858篇
  1975年   914篇
  1974年   1256篇
  1973年   1068篇
  1972年   1146篇
  1971年   1304篇
  1970年   1773篇
  1969年   1384篇
  1968年   1197篇
  1967年   1240篇
  1966年   1146篇
  1965年   862篇
  1964年   263篇
  1959年   487篇
  1958年   846篇
  1957年   604篇
  1956年   492篇
  1955年   449篇
  1954年   496篇
  1948年   333篇
排序方式: 共有10000条查询结果,搜索用时 31 毫秒
991.
Five additional species of wood rotting basidiomycetes on Arizona junipers are described and illustrated.   All cause a white rot of dead, fallen trees. Leptosporomyces juniperinus is proposed as a new species. Vararia fibra is reported from the United States for the first time.  相似文献   
992.
We sampled both subspecies of the Idaho ground squirrel ( Spermophilus brunneus ) to document the larger ectoparasites of this rare endemic. S. b. brunneus was host (+ = new host record, ? = new Idaho record) to 4 flea species ( Neopsylla inopina + , Oropsylla idahoensis + , O. tuberculata , and Thrassis pandorae +), 1 tick ( Ixodes sculptus +), and an eyeworm (Nematoda: Rhabditis orbitalis ? + , also 1st records from Seiuridae); S. b. endemicus was host to a louse species ( Neohaematopinus laeviusculus +), 5 flea taxa ( Rhadinopsylla sp. + , O. t. tuberculata, Thrassis f. francisi + , T. f. barnest + , and T. f. rockwoodi ), and a mite ( Androlaelaps fahrenholzi +). Spermophilus brunneus had fewer known ectoparasite species than other congeners. Although all of their parasites had many other hosts, S. b. endemicus and S. b. brunneus shared only a single parasite species in common, whereas all but one of their ectoparasites also occurred on the closely related Townsend's ground squirrel ( S. townsendii ). The proportion of parasitized individuals and the parasite loads per individual were significantly lower in S. b. brunneus , which lives in small, isolated populations, than in S. b. endemicus , which has larger, less fragmented populations, suggesting a relationship between host population structure, parasite loads, and parasite species diversity. All but one of the flea species have been linked to plague transmission.  相似文献   
993.
The occurrence of infectious disease represents a failure of the immune system, a failure that must be prevented by effective vaccination or remedied by treatment. Vaccination against acute diseases such as smallpox and polio are very effective, due to the rapid and increased immune response of vaccinated individuals upon natural infection. In contrast, effective vaccination against intracellular pathogens that cause chronic diseases, such as the leishmaniases, tuberculosis and AIDS, has not been achieved. Clinical observations suggest cell-mediated, Th1 responses, exclusive of antibody production and the generation of Th2 cells, are optimally protective against these intracellular pathogens. Effective vaccination must ensure the generation of such a protective response. We explore here whether understanding very broad features of the regulation of the immune response can accommodate modern findings on the immunological features of these diseases, and provide a perspective within which strategies for effective vaccination and treatment can be developed.  相似文献   
994.
Platelets interact with bacterial pathogens through a wide array of cellular and molecular mechanisms. The consequences of this interaction may significantly influence the balance between infection and immunity. On the one hand, recent data indicate that certain bacteria may be capable of exploiting these interactions to gain a virulence advantage. Indeed, certain bacterial pathogens appear to have evolved specific ways in which to subvert activated platelets. Hence, it is conceivable that some bacterial pathogens exploit platelet responses. On the other hand, platelets are now known to possess unambiguous structures and functions of host defense effector cells. Recent discoveries emphasize critical features enabling such functions, including expression of toll-like receptors that detect hallmark signals of bacterial infection, an array of microbicidal peptides, as well as other host defense molecules and functions. These concepts are consistent with increased risk and severity of bacterial infection as correlates of clinical abnormalities in platelet quantity and quality. In these respects, the molecular and cellular roles of platelets in host defense against bacterial pathogens are explored with attention on advances in platelet immunobiology.  相似文献   
995.
996.
Normal 0 false false false EN-US X-NONE X-NONE MicrosoftInternetExplorer4 st1\:*{behavior:url(#ieooui) } /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-qformat:yes; mso-style-parent:""; mso-padding-alt:0in 5.4pt 0in 5.4pt; mso-para-margin:0in; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:11.0pt; font-family:"Calibri","sans-serif"; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-fareast-font-family:"Times New Roman"; mso-fareast-theme-font:minor-fareast; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-bidi-font-family:"Times New Roman"; mso-bidi-theme-font:minor-bidi;} The relative abundance and habitat affinities of breeding and migratory waterfowl were documented for a 16,556 ha (40,880 acre) area of the Navajo Indian Reservation, San Juan County, New Mexico. The objective of the 1973 – 1974 study was to obtain baseline data for use as part of an environmental assessment for coal gasification plants and an associated strip mine proposed for an area not previously described in ornithological journals. Roadside breeding - bird surveys resulted in the observation of 26 species of birds, of which the horned lark was most abundant. Additional breeding - bird observations were made during afternoon reconnaissance surveys around stock ponds and arroyos, and by a helicopter survey of cliff - nesting raptors. Nine of 30 raptor nests located were active. Migratory waterfowl surveys were made in September and November at four stock ponds and a marsh on the study area. Peak waterfowl numbers were present in September, when teal and shovelers were the most abundant species. The importance of stock ponds to breeding and migratory birds and the significance of cliffs to nesting raptors were discussed. Details of observations made for five species of birds designated ";threatened"; or ";status undetermined"; were presented.     相似文献   
997.
Streambed surveys were conducted along the upper Colorado River, Colorado, to describe the distributions of Claassenia sabulosa larvae in relation to current speed and to determine their diets. We also addressed diel feeding periodicity by sampling during both day and night. Claassenia sabulosa was more abundant in riffle habitats than in runs. A positive relationship existed between C. sabulosa abundance and stream current, with larval size increasing with current speed. Chironomidae, Baetidae, and Simulidae collectively accounted for 93% of the prey found in stonefly guts; however, these categories were not consumed equally by all C. sabulosa . Smaller C. sabulosa primarily ate chironomids, and larger individuals consumed more baetids. Only a slight difference existed in the percentage of empty guts between night- and day-collected stoneflies, and ranges of prey per gut at night were higher than those in the day, suggesting that these stoneflies may forage more intensively at night.  相似文献   
998.
P2X4 and P2X7 receptors are ATP-gated ion channels that are co-expressed in alveolar epithelial type I cells. Both receptors are localized to the plasma membrane and partly associated with lipid rafts. Here we report on our study in an alveolar epithelial cell line of the molecular organization of P2X7R and P2X4R receptors and the effect of their knockdown. Native gel electrophoresis reveals three P2X7R complexes of ~430, ~580 and ~760 kDa. The latter two correspond exactly in size to signals of Cav-1, the structural protein of caveolae. Interestingly knockdown of P2rx7 affects protein levels, the intracellular distribution and the supramolecular organization of Cav-1 as well as of P2X4R, which is mainly detected in a complex of ~430 kDa. Our data suggest upregulation of P2X4R as a compensatory mechanism of P2X7R depletion.  相似文献   
999.
B M Jakosky  R J Phillips 《Nature》2001,412(6843):237-244
There is substantial evidence that the martian volatile inventory and climate have changed markedly throughout the planet's history. Clues come from areas as disparate as the history and properties of the deep interior, the composition of the crust and regolith, the morphology of the surface, composition of the present-day atmosphere, and the nature of the interactions between the upper atmosphere and the solar wind. We piece together the relevant observations into a coherent view of the evolution of the martian climate, focusing in particular on the observations that provide the strongest constraints.  相似文献   
1000.
公路基本建设事业的快速发展,对公路养护工程提出了更高的要求,公路养护不断遇到新的难题,面对困难和挑战。文章结合本地区公路养护实际工作实践,对公路养护管理存在的问题进行了分析,并探讨了相应对策。  相似文献   
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号