Reduced foetal calcium without skeletal malformations in rats following high maternal doses of a strontium salt

Zusammenfassung nachweis, dass hohe Strontiumkonzentrationen die Kalzifikation der, Knochen neugeborener Mäuse, und diejenige in Knochengewebskulturen hemmen. Im Gegensatz dazu und zu anderen knochenaffinen metallen wirkt Strontiumnitrat in Dosen von25, 50, 100 and 200 mg/kg, verabreicht während des 9. bis 19. Trächtigkeitstages, bei Ratten nicht teratogen.

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We are indebted to Mr.K. L. Murray of the Government Chemist's Laboratory for analyzing tissue samples by atomic absorption spectrophotometry. We are also grateful toDr. R. F. Crampton, Director of BIBRA, for his interest and advice in this work.     

Mannosidohydroxystreptomycin fromStreptomyces sp.

Riassunto Viene descritto l'isolamento e lo studio chimico della mannosidoossistreptomicina, presente, insieme con ossistreptomicina, streptidina e toiocamicina, nelle colture delloStreptomyces 86. Il nuovo antibiotico ed il suo diidroderivato presentano una attività antibatterica paragonabile a quella di streptomicina e di ossistreptomicina.     

Primary division ratio of umbilical arteries and vein of the human placenta in abnormal states of pregnancy and development

Zusammenfassung Es wird gezeigt, dass die Verzweigungen der Nabelschnurgefässe am übergang auf die Membrana chorii bei Zwillingsschwangerschaften, Fehlbildungen des Fetus sowie beim Hydramnion signifikante Abweichungen von der Norm zeigen.     

Variations in cardiac noradrenaline content during sodium loading in hypertension prone and resistant rats

Summary The cardiac catecholamine content of Sabra rats and their 2 genetically derived substrains, hypertension prone and resistant rats, was studied by high pressure liquid chromatography and electrochemical detection. Both in the control period and after sodium and DOCA administration the cardiac noradrenaline level is higher in hypertension resistant rats than in Sabra rats, and also higher than in hypertension prone rats. This finding suggests that a reduction of the cardiac sympathetic nervous tone is involved in the genetic resistance to sodium.