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141.
A microRNA component of the p53 tumour suppressor network 总被引:5,自引:0,他引:5
142.
143.
基于MVC模型的SVG生产实时监控系统设计与实现 总被引:1,自引:0,他引:1
针对传统生产实时监控系统灵活性差的问题,应用SVG技术进行了改进,适用于异构系统环境;并结合MVC架构设计并实现了扩展性高、移植性好、灵活性强的J2EE实时监控系统。 相似文献
144.
LQ YingzhongInst. for Techno-Economics Energy System Analysis. P.O. Box Beijing China 《系统工程与电子技术(英文版)》1991,(1)
The long-term energy demand in China and the-Chinese share in global CO2 emission are forecasted on the basis of scenarios of population growth and economy development up to 2050 proposed in view of the interaction of energy, economy, environment and social development. The total energy demand in 2050 will reach 4.4~ 5.4 billion tce. It is shown in energy supply analysis that coal is China's major energy in primary energy supply. The share of CO2 emission in the future Chinese energy system will be out of proportion to its energy consumption share because of the high persentage of coal to be consumed. It will reach about 27%. The nuclear option which would replace 30.7% of coal in the total primary energy supply will reduce the share by 9.8%. So the policy considerations on the future Chinese energy system is of great importance to the global CO2 issues. 相似文献
145.
基于相对论性激光-等离子体动力学理论和PIC方法建立了激光入射等离子弧柱的模型,该模型描述了激光入射等离子弧后粒子的运动,并模拟了弧柱形态的变化。通过改变激光的平均功率、脉冲宽度以及重复频率,模拟等离子弧柱形态变化,得到的激光参数对等离子弧柱形态的影响规律。通过控制弧柱的直径可以提高材料的熔积性能。计算结果表明增大激光平均功率、脉冲宽度,可以更深地压缩等离子弧;但是,重复频率的影响则会出现波动现象。激光等离子复合加工更适合于精细加工。 相似文献
146.
Zhou XianminShanghai Research & Development Centre Guil in Road Shanghai P.R.China 《系统工程与电子技术(英文版)》1993,(4)
Computer simulation models may by used to gain further information about missile performance variability. Model validation is an important aspect of the test program for a missile system. Validation provides a basis for confidence in the model's results and is a necessary step if the model is to be used to draw inference about the behavior of the real missile. This paper is a review of methods useful for validation of computer simulation models of missile systems and provides a new method with high degree of confidence for validation of computer simulation models of missile systems. Some examples of the use of the new method in validating computer simulation models are given. 相似文献
147.
148.
A dipole mode in the tropical Indian Ocean 总被引:203,自引:0,他引:203
For the tropical Pacific and Atlantic oceans, internal modes of variability that lead to climatic oscillations have been recognized, but in the Indian Ocean region a similar ocean-atmosphere interaction causing interannual climate variability has not yet been found. Here we report an analysis of observational data over the past 40 years, showing a dipole mode in the Indian Ocean: a pattern of internal variability with anomalously low sea surface temperatures off Sumatra and high sea surface temperatures in the western Indian Ocean, with accompanying wind and precipitation anomalies. The spatio-temporal links between sea surface temperatures and winds reveal a strong coupling through the precipitation field and ocean dynamics. This air-sea interaction process is unique and inherent in the Indian Ocean, and is shown to be independent of the El Ni?o/Southern Oscillation. The discovery of this dipole mode that accounts for about 12% of the sea surface temperature variability in the Indian Ocean--and, in its active years, also causes severe rainfall in eastern Africa and droughts in Indonesia--brightens the prospects for a long-term forecast of rainfall anomalies in the affected countries. 相似文献
149.
Bone marrow cells regenerate infarcted myocardium 总被引:455,自引:0,他引:455
Orlic D Kajstura J Chimenti S Jakoniuk I Anderson SM Li B Pickel J McKay R Nadal-Ginard B Bodine DM Leri A Anversa P 《Nature》2001,410(6829):701-705
Myocardial infarction leads to loss of tissue and impairment of cardiac performance. The remaining myocytes are unable to reconstitute the necrotic tissue, and the post-infarcted heart deteriorates with time. Injury to a target organ is sensed by distant stem cells, which migrate to the site of damage and undergo alternate stem cell differentiation; these events promote structural and functional repair. This high degree of stem cell plasticity prompted us to test whether dead myocardium could be restored by transplanting bone marrow cells in infarcted mice. We sorted lineage-negative (Lin-) bone marrow cells from transgenic mice expressing enhanced green fluorescent protein by fluorescence-activated cell sorting on the basis of c-kit expression. Shortly after coronary ligation, Lin- c-kitPOS cells were injected in the contracting wall bordering the infarct. Here we report that newly formed myocardium occupied 68% of the infarcted portion of the ventricle 9 days after transplanting the bone marrow cells. The developing tissue comprised proliferating myocytes and vascular structures. Our studies indicate that locally delivered bone marrow cells can generate de novo myocardium, ameliorating the outcome of coronary artery disease. 相似文献
150.
Synapsin I bundles F-actin in a phosphorylation-dependent manner 总被引:12,自引:0,他引:12
Synapsin I is a neuron-specific phosphoprotein localized to the cytoplasmic surface of synaptic vesicles. This phosphoprotein is a major substrate for cyclic AMP-dependent and calcium/calmodulin-dependent protein kinases. Its state of phosphorylation can be altered both in vivo and in vitro by a variety of physiological and pharmacological manipulations known to affect synaptic function. Recent direct evidence suggests that it may be involved in the regulation of neurotransmitter release from the nerve terminal. In the nerve terminal, synaptic vesicles are embedded in a cytoskeletal network, consisting in part of actin. We report here the ability of the dephospho-form of synapsin I to bundle F-actin. This bundling activity is reduced when synapsin I is phosphorylated by cAMP-dependent protein kinase and virtually abolished when it is phosphorylated by calcium/calmodulin-dependent protein kinase II or by both kinases. These results, demonstrating an interaction of synapsin I with actin in vitro, support the possibility that synapsin I is involved in clustering of synaptic vesicles at the presynaptic terminal and that the phosphorylation of synapsin I may be involved in regulating the translocation of synaptic vesicles to their sites of release. 相似文献