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671.
Surveying the propagation path loss behavior of Shenzhen city and from the data recorded we can obtain the city’s path loss
slopes, which can be comparatively regarded as the reliable bases of system design.
Biography: ZHANG Yuan-qiao(1975-), male, Master candidate. Research direction: electronic magnetic theory. 相似文献
672.
根据岩性、沉积构造、古生物化石和地球化学标志,系统分析了博格达山南缘广泛发育的二叠系芦草沟组的沉积环境。研究表明:博格达山南缘芦草沟组深湖相沉积十分发育,并在此背景上沉积了近岸浊积扇和远岸浊积扇。其中,深湖相暗色泥、页岩和油页岩构成了良好的烃源岩。同时,认为吐哈盆地前侏罗系具有良好的勘探前景。 相似文献
673.
Ageing, fitness and neurocognitive function. 总被引:18,自引:0,他引:18
A F Kramer S Hahn N J Cohen M T Banich E McAuley C R Harrison J Chason E Vakil L Bardell R A Boileau A Colcombe 《Nature》1999,400(6743):418-419
674.
675.
The motility of the gastrointestinal tract consists of local, non-propulsive mixing (pendular or segmental) and propulsive (peristaltic) movements. It is generally considered that mixing movements are produced by intrinsic pacemakers which generate rhythmic contractions, and peristalsis by intrinsic excitatory and inhibitory neural reflex pathways, but the relationship between mixing and peristalsis is poorly understood. Peristalsis is compromised in mice lacking interstitial cells of Cajal, suggesting that these pacemaker cells may also be involved in neural reflexes. Here we show that mixing movements within longitudinal muscle result from spontaneously generated waves of elevated internal calcium concentration which originate from discrete locations (pacing sites), spread with anisotropic conduction velocities in al directions, and terminate by colliding with each other or with adjacent neurally suppressed regions. Excitatory neural reflexes control the spread of excitability by inducing new pacing sites and enhancing the overall frequency of pacing, whereas inhibitory reflexes suppress the ability of calcium waves to propagate. We provide evidence that the enteric nervous system organizes mixing movements to generate peristalsis, linking the neural regulation of pacemakers to both types of gut motility. 相似文献
676.
677.
Aspirin causes short-lived inhibition of bradykinin-stimulated prostacyclin production in man 总被引:3,自引:0,他引:3
Acetylsalicylic acid (aspirin) inhibits prostanoid synthesis by irreversible acetylation of fatty acid cyclooxygenase (EC 1.14.99.1). It thereby inhibits synthesis of pro-aggregatory thromboxane A2 (TXA2) by platelets and is widely used in the treatment and prophylaxis of vascular disease. Its efficacy, however, may be reduced since it also inhibits formation of prostacyclin (PGI2) which is a vasodilator and anti-aggregatory agent. There is uncertainty over the optimum dose regimen for aspirin since although it inhibits platelet thromboxane production for many days, the magnitude and duration of its effect on PGI2 production by vascular endothelium in vivo is unknown. Resting plasma concentrations of PGI2 (measured as the stable hydrolysis product 6-oxo-PGF1 alpha) are at or below the limit of sensitivity of the most sensitive assays and cannot therefore be used to demonstrate a reduction in production. Bradykinin stimulates PGI2 synthesis by cultured human vascular endothelial cells and we have shown that it stimulates PGI2 production by man in vivo. We report here that an oral dose of aspirin (600 mg) causes rapid and substantial inhibition of bradykinin-stimulated PGI2 production, but recovery occurs within 6 hours; this implies that endothelial PGI2 synthesis would be spared most of the time during dosing once daily with even this relatively large dose of aspirin. 相似文献
678.
679.
Calmodulin is a regulator of several calcium-dependent cellular processes. It has been suggested that it plays a role in the mechanism of secretion. Employing an indirect immunoperoxidase technique at the light microscope level, this study demonstrates the presence of calmodulin in several exocytotic cells (mast cells, thyroid follicular cells, neurohypophyseal neurosecretory terminals, pancreatic beta-cells and pancreatic acinus cells) in rat and man. The positive staining reaction for calmodulin was granular and at least in the case of rat mast cells it appeared to be associated with the granule membrane. 相似文献
680.