砂体非线性分布的定量研究方法

介绍了分形几何学和分形地质统计学,并以大庆榆树林油田的砂体精细定量描述为例,利用分形地质统计学方法,对大庆榆树林油田砂体的分形分布进行了定量表征,为油田开发中的砂体非线性分布的数学定量表征提供了一种比较实用和可行的方法.     

A New interpretation of Michael Polanyi''s theory of tacit knowing: Integrative philosophy with ‘Intellectual Passions’

According to my interpretation, based on the entirety of Michael Polanyi's epistemological works, his theory of tacit knowing is conceived of as three models tied together by the central feature of Intellectual Passions as integrator. The models are progressively refined forms of his first conception of tacit knowing: ‘we know more than we can tell’. The three models are: the Gestalt-Perception Model based on the gestalt notion of part-whole relations, the Action-Guiding Model incorporating the phenomenological-existential notion of intentional action, and the Semiotic Model, an abstract conception of action directed to meaning showing that tacit knowing has a ‘from-to structure’ (from subsidiary awareness to focal awareness). In the Semiotic Model integration is named by the logical term ‘inference’. Polanyi's conception of reality and his theory of truth are introduced linked to the models, to show why his epistemology is not subjectivist and his theory of truth is not relativist.     

Angiotensin-converting enzyme 2 is a functional receptor for the SARS coronavirus

Spike (S) proteins of coronaviruses, including the coronavirus that causes severe acute respiratory syndrome (SARS), associate with cellular receptors to mediate infection of their target cells. Here we identify a metallopeptidase, angiotensin-converting enzyme 2 (ACE2), isolated from SARS coronavirus (SARS-CoV)-permissive Vero E6 cells, that efficiently binds the S1 domain of the SARS-CoV S protein. We found that a soluble form of ACE2, but not of the related enzyme ACE1, blocked association of the S1 domain with Vero E6 cells. 293T cells transfected with ACE2, but not those transfected with human immunodeficiency virus-1 receptors, formed multinucleated syncytia with cells expressing S protein. Furthermore, SARS-CoV replicated efficiently on ACE2-transfected but not mock-transfected 293T cells. Finally, anti-ACE2 but not anti-ACE1 antibody blocked viral replication on Vero E6 cells. Together our data indicate that ACE2 is a functional receptor for SARS-CoV.