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Measurements taken at three-year intervals between 1977 and 1985 of channel morphology and vegetation cover between sections inside and outside a cattle exclosure showed that channels increased in depth and width on all plots. Tree canopy cover decreased significantly between 1977 and 1985, but changes in density of trees and shrubs and herbaceous cover were small. Exclusion of cattle use did not prevent channel erosion or deterioration of vegetation; rather, changes were attributed to a wildfire in the headwaters and subsequent storm events that temporarily upset the dynamic equilibrium of the stream. 相似文献
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Exclusion of linkage to 5q11-13 in families with schizophrenia and other psychiatric disorders 总被引:2,自引:0,他引:2
S D Detera-Wadleigh L R Goldin R Sherrington I Encio C de Miguel W Berrettini H Gurling E S Gershon 《Nature》1989,340(6232):391-393
Recently a linkage study on five Icelandic and two English pedigrees has provided evidence for a dominant gene for schizophrenia on 5q11-13 (ref. 1). In that study, families with bipolar illness were not included. Using the same probes, two similar but independent investigations on one Swedish pedigree and on fifteen Scottish families excluded linkage to schizophrenia. To evaluate whether the susceptibility gene on 5q11-13 is a common cause of schizophrenia in other populations, we examined five affected North American pedigrees using probes to the D5S39, D5S76 and dihydrofolate reductase loci. Two families in the present series had cases of bipolar disorder. We found that linkage can be excluded by multipoint analysis. These results, taken together, suggest that the disease gene on 5q11-13 does not account for most cases of familial schizophrenia. 相似文献
57.
Miguel A. Granada 《Studies in history and philosophy of science》2004,35(1):91-114
This paper1 studies the different conceptions of both centrality and the principle or starting point of motion in the Universe held by Aristotle and later on by Copernicanism until Kepler and Bruno. According to Aristotle, the true centre of the Universe is the sphere of the fixed stars. This is also the starting point of motion. From this point of view, the diurnal motion is the fundamental one. Our analysis gives pride of place to De caelo II, 10, a chapter of Aristotle’s text which curiously allows an ‘Alpetragian’ reading of the transmission of motion.In Copernicus and the Copernicans, natural centrality is identified with the geometrical centre and, therefore, the Sun is acknowledged as the body through which the Deity acts on the world and it also plays the role of the principle and starting point of cosmic motion. This motion, however, is no longer diurnal motion, but the annual periodical motion of the planets. Within this context, we pose the question of to what extent it is possible to think that, before Kepler, there is a tacit attribution of a dynamic or motive role to the Sun by Copernicus, Rheticus, and Digges.For Bruno, since the Universe is infinite and homogeneous and the relationship of the Deity with it is one of indifferent presence everywhere, the Universe has no absolute centre, for any point is a centre. By the same token, there is no place that enjoys the prerogative of being—as being the seat of God—the motionless principle and starting point of motion. 相似文献
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Phylogeny and rapid Northern and Southern Hemisphere speciation of goldfinches during the Miocene and Pliocene Epochs 总被引:5,自引:0,他引:5
A. Arnaiz-Villena M. Álvarez-Tejado V. Ruíz-del-Valle C. García-de-la-Torre P. Varela M. J. Recio S. Ferre J. Martínez-Laso 《Cellular and molecular life sciences : CMLS》1998,54(9):1031-1041
Mitochondrial cytochrome b (cyt b) from 25 out of 31 extant goldfinches, siskins, greenfinches and redpolls (genus Carduelis) has been sequenced from living samples taken around the world, specimens have also been photographed. Phylogenetic analysis
consistently gave the same groups of birds, and this grouping was generally related to geographical proximity. It has been
supposed that Pleistocene glaciations played a crucial role in the origin of extant diversity and distribution of Northern
Hemisphere vertebrates. Molecular comparison of most extant songbird species belonging to the genus Carduelis does not support this assertion. The fossil record of chicken and pheasant divergence time has been used to calibrate the
molecular clock; cyt b DNA dendrograms suggest that speciation in Carduelinae birds occurred during the Miocene and Pliocene
Epochs (9 – 2 million years ago) in both the Northern and Southern Hemispheres. Only about 4% average amount of nucleotide
substitution per lineage is found between the most distant Carduelis species; this suggests a remarkably rapid radiation when compared with the radiation of other passerine songbird genera.
In addition, a continuum of small songbird speciation may be found during the Miocene Epoch in parallel with speciation of
other orders (i.e. Galliformes, chicken/pheasant). Pleistocene glaciations may have been important in subspeciation (i.e.
Eastern European grey-headed goldfinches/Western European black-headed goldfinches) and also in ice-induced vicariance (isolation)
(i.e. siskin in Western Europe vs. siskin in Far East Asia) around the world. European isolated Serinus citrinella (citril finch) is not a canary, but a true goldfinch. South American siskins have quickly radiated in the last 4 million
years coinciding with the emergence of the Isthmus of Panama; probably, a North American siskin related to C. notata invaded a suitable and varied biotope (the South American island) for Carduelis birds. North American goldfinches may be renamed as siskins, because they have a distant genetic relationship with European
goldfinches. Genus Acanthis could be dropped, and thus redpolls should be separated from twite and linnet, the latter (Europeans) probably being related
to American goldfinches. Also, reproductive barriers are observed between closely related species and not between other more
distant ones. Finally, a tentative classification for genus Carduelis species is suggested.
Received 6 March 1998; received after revision 3 July 1998; accepted 7 July 1998 相似文献
60.
Galagan JE Calvo SE Cuomo C Ma LJ Wortman JR Batzoglou S Lee SI Baştürkmen M Spevak CC Clutterbuck J Kapitonov V Jurka J Scazzocchio C Farman M Butler J Purcell S Harris S Braus GH Draht O Busch S D'Enfert C Bouchier C Goldman GH Bell-Pedersen D Griffiths-Jones S Doonan JH Yu J Vienken K Pain A Freitag M Selker EU Archer DB Peñalva MA Oakley BR Momany M Tanaka T Kumagai T Asai K Machida M Nierman WC Denning DW Caddick M Hynes M Paoletti M Fischer R Miller B Dyer P Sachs MS Osmani SA Birren BW 《Nature》2005,438(7071):1105-1115
The aspergilli comprise a diverse group of filamentous fungi spanning over 200 million years of evolution. Here we report the genome sequence of the model organism Aspergillus nidulans, and a comparative study with Aspergillus fumigatus, a serious human pathogen, and Aspergillus oryzae, used in the production of sake, miso and soy sauce. Our analysis of genome structure provided a quantitative evaluation of forces driving long-term eukaryotic genome evolution. It also led to an experimentally validated model of mating-type locus evolution, suggesting the potential for sexual reproduction in A. fumigatus and A. oryzae. Our analysis of sequence conservation revealed over 5,000 non-coding regions actively conserved across all three species. Within these regions, we identified potential functional elements including a previously uncharacterized TPP riboswitch and motifs suggesting regulation in filamentous fungi by Puf family genes. We further obtained comparative and experimental evidence indicating widespread translational regulation by upstream open reading frames. These results enhance our understanding of these widely studied fungi as well as provide new insight into eukaryotic genome evolution and gene regulation. 相似文献