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51.
Salicornia rubra Nels. (Chenopodiaceae) is a salt-tolerant annual species occurring in salt playas of the Great Basin desert in western United States. It forms pioneer communities on the most saline location of an inland salt playa at Goshen, Utah. Seeds of Salicornia rubra are capable of germinating at 1000 mM NaCl at 25-35° C alternating temperature regime. Dormancy-regulating chemicals were evaluated for their ability to alleviate the innate and salinityenforced dormancy in seeds of Salicornia rubra . Betaine, GA3, kinetin, fusicoccin, ethephon, thiourea, proline, and nitrate had no effect in alleviating primary dormancy. Increases in NaCl concentration progressively inhibited germination of Salicornia rubra seeds. Ethephon, fusicoccin, GA3, kinetin, thiourea, and nitrate promoted germination under low saline conditions. At high salinity fusicoccin had no effect, whereas GA3, kinetin, and ethephon substantially alleviated salinity effects. Application of these dormancy-regulating compounds could be of practical value in seeding a saline area for restoration purposes, particularly under high saline conditions. 相似文献
52.
Dystrophin expression in the mdx mouse restored by stem cell transplantation. 总被引:180,自引:0,他引:180
E Gussoni Y Soneoka C D Strickland E A Buzney M K Khan A F Flint L M Kunkel R C Mulligan 《Nature》1999,401(6751):390-394
The development of cell or gene therapies for diseases involving cells that are widely distributed throughout the body has been severely hampered by the inability to achieve the disseminated delivery of cells or genes to the affected tissues or organ. Here we report the results of bone marrow transplantation studies in the mdx mouse, an animal model of Duchenne's muscular dystrophy, which indicate that the intravenous injection of either normal haematopoietic stem cells or a novel population of muscle-derived stem cells into irradiated animals results in the reconstitution of the haematopoietic compartment of the transplanted recipients, the incorporation of donor-derived nuclei into muscle, and the partial restoration of dystrophin expression in the affected muscle. These results suggest that the transplantation of different stem cell populations, using the procedures of bone marrow transplantation, might provide an unanticipated avenue for treating muscular dystrophy as well as other diseases where the systemic delivery of therapeutic cells to sites throughout the body is critical. Our studies also suggest that the inherent developmental potential of stem cells isolated from diverse tissues or organs may be more similar than previously anticipated. 相似文献
53.
Low power and real time very large scale integration(VLSI) architectures of motion estimation(ME) algorithms for mobile devices and applications are presented.The power reduction is achieved by devising a novel correction recovery mechanism based on algorithms which allow the use of reduced bit sum of absolute difference(RBSAD) metric for calculating matching error and conversion to full resolution sum of absolute difference(SAD) metric whenever necessary.Parallel and pipelined architectures for high throughput of full search ME corresponding to both the full resolution SAD and the generalized RBSAD algorithm are synthesized using Xilinx Synthesis Tools(XST),where the ME designs based on reduced bit(RB) algorithms demonstrate the reduction in power consumption up to 45% and/or the reduction in area up to 38%. 相似文献
54.
R A Khan 《Experientia》1980,36(10):1193-1194
The bone mineral extraction of technetium-99m-methylene diphosphonate (99mTc-MDP), and blood supply of Krypton-81m (81mKr) have been compared in normal and osteotomy regions of the canine tibia. A partial osteotomy was carried out under aseptic conditions, and isotopic measurements made over a period of 123 days. Both blood flow and bone mineral extraction increase after a partial osteotomy. 相似文献
55.
Moharram A Khan 《吉林大学学报(理学版)》2000,(3)
证明若分配生成近环 R满足 xy=p( x,y)性质 ,则 R必可换 ,其中 p( x,y)是 αixpiynixqi的有限和 ,项数 ,αi,pi,ni,qi 均随 x,y∈ R变化 ,且 αi,pi,qi≥ 1 ,ni>1 相似文献
56.
Regular, moderate consumption of red wine is linked to a reduced risk of coronary heart disease and to lower overall mortality, but the relative contribution of wine's alcohol and polyphenol components to these effects is unclear. Here we identify procyanidins as the principal vasoactive polyphenols in red wine and show that they are present at higher concentrations in wines from areas of southwestern France and Sardinia, where traditional production methods ensure that these compounds are efficiently extracted during vinification. These regions also happen to be associated with increased longevity in the population. 相似文献
57.
Muzny DM Scherer SE Kaul R Wang J Yu J Sudbrak R Buhay CJ Chen R Cree A Ding Y Dugan-Rocha S Gill R Gunaratne P Harris RA Hawes AC Hernandez J Hodgson AV Hume J Jackson A Khan ZM Kovar-Smith C Lewis LR Lozado RJ Metzker ML Milosavljevic A Miner GR Morgan MB Nazareth LV Scott G Sodergren E Song XZ Steffen D Wei S Wheeler DA Wright MW Worley KC Yuan Y Zhang Z Adams CQ Ansari-Lari MA Ayele M Brown MJ Chen G Chen Z Clendenning J Clerc-Blankenburg KP Chen R Chen Z Davis C Delgado O Dinh HH Dong W 《Nature》2006,440(7088):1194-1198
After the completion of a draft human genome sequence, the International Human Genome Sequencing Consortium has proceeded to finish and annotate each of the 24 chromosomes comprising the human genome. Here we describe the sequencing and analysis of human chromosome 3, one of the largest human chromosomes. Chromosome 3 comprises just four contigs, one of which currently represents the longest unbroken stretch of finished DNA sequence known so far. The chromosome is remarkable in having the lowest rate of segmental duplication in the genome. It also includes a chemokine receptor gene cluster as well as numerous loci involved in multiple human cancers such as the gene encoding FHIT, which contains the most common constitutive fragile site in the genome, FRA3B. Using genomic sequence from chimpanzee and rhesus macaque, we were able to characterize the breakpoints defining a large pericentric inversion that occurred some time after the split of Homininae from Ponginae, and propose an evolutionary history of the inversion. 相似文献
58.
京都协议已确认并应用战略战术措施来减少温室气的排放,因此,城市交通系统规划人员不得不寻求一种革新的方法来满足京都协议的要求。本文包括四部分:第一部分简要介绍了环境可持续的城市交通的概念,油耗,温室气体排放和京都协议的要求;第二部分描述了温室气体排放估测所需的方法,并指出了在实践中存在的缺陷,第三部分阐述了如何应用EMME/2作为平台来估测室气体的排放;最后第四部分作了总结。 相似文献
59.
Sanjay Kumar Bharti Irfan Khan Taraswi Banerjee Joshua A. Sommers Yuliang Wu Robert M. Brosh Jr. 《Cellular and molecular life sciences : CMLS》2014,71(14):2625-2639
In 2010, a new recessive cohesinopathy disorder, designated Warsaw breakage syndrome (WABS), was described. The individual with WABS displayed microcephaly, pre- and postnatal growth retardation, and abnormal skin pigmentation. Cytogenetic analysis revealed mitomycin C (MMC)-induced chromosomal breakage; however, an additional sister chromatid cohesion defect was also observed. WABS is genetically linked to bi-allelic mutations in the ChlR1/DDX11 gene which encodes a protein of the conserved family of Iron–Sulfur (Fe–S) cluster DNA helicases. Mutations in the budding yeast ortholog of ChlR1, known as Chl1, were known to cause sister chromatid cohesion defects, indicating a conserved function of the gene. In 2012, three affected siblings were identified with similar symptoms to the original WABS case, and found to have a homozygous mutation in the conserved Fe–S domain of ChlR1, confirming the genetic linkage. Significantly, the clinically relevant mutations perturbed ChlR1 DNA unwinding activity. In addition to its genetic importance in human disease, ChlR1 is implicated in papillomavirus genome maintenance and cancer. Although its precise functions in genome homeostasis are still not well understood, ongoing molecular studies of ChlR1 suggest the helicase plays a critically important role in cellular replication and/or DNA repair. 相似文献
60.
Ahmed ZM Masmoudi S Kalay E Belyantseva IA Mosrati MA Collin RW Riazuddin S Hmani-Aifa M Venselaar H Kawar MN Tlili A van der Zwaag B Khan SY Ayadi L Riazuddin SA Morell RJ Griffith AJ Charfedine I Caylan R Oostrik J Karaguzel A Ghorbel A Riazuddin S Friedman TB Ayadi H Kremer H 《Nature genetics》2008,40(11):1335-1340