Characterization of the rough endoplasmic reticulum ribosome-binding activity.

The rough endoplasmic reticulum membranes of mammalian cells contain specific ribosome-binding sites. A purification to apparent homogeneity of a negatively charged protein (ERp180) of relative molecular mass 180,000 (180 K) was reported which was proposed to function as a rough endoplasmic reticulum ribosome receptor. We report here that ribosome-binding site activity quantitatively solubilized from rough endoplasmic reticulum membranes does not cofractionate with ERp180. By contrast, ribosome-binding site activity fractionates as a much smaller, positively charged protein.     

PDE-Based Medial Axis Extraction and Shape Manipulation of Arbitrary Meshes

Shape skeletonization （i.e., medial axis extraction） is powerful in many visual computing applications, such as pattern recognition, object segmentation, registration, and animation. In this paper, the authors expand the use of diffusion equations combined with distance field information to approximate medial axes of arbitrary 3D differential properties. It offers an alternative solids represented by polygonal meshes based on their but natural way for medial axis extraction for commonly used 3D polygonal models. By solving the PDE along time axis, this system can not only quickly extract diffusion-based medial axes of input meshes, but also allow users to visualize the extraction process at each time step. In addition, the proposed model provides users a set of manipulation toolkits to sculpt extracted medial axes, then use diffusion-based techniques to recover corresponding deformed shapes according to the original input datasets. This skeleton-based shape manipulation offers a fast and easy way for animation and deformation of complicated mesh objects.     

Systemic Intervention in a University Department: Reflections on Arrested Action Research

This paper reflects on my experience as an insider researcher attempting to use critical systems ideas and practices to promote quality improvement in a university engineering department. Reflection is a key part of learning. This paper is intended to contribute to critically, self-reflective learning for the community of systems practitioners. These reflections on my questions about participation, ethics, politics of process, and the choices and actions resulting from them may help others to formulate their own. The complexity of systems practice places substantial demands on the researcher, particularly in the case of insider, practitioner research. Nevertheless, the exploration of critical systems approaches to critique boundaries and structure ‘problems’ in the core aspects of higher education in locally meaningful ways should continue. While demanding, it still can work to promote learning about authentic quality.     

Rare Earth Doped Polymer Waveguide Materials and Devices

1 Results Rare earth doped waveguide amplifiers and devices have been demonstrated in silica, crystal and other glass hosts. These rare earth doped optical waveguide devices are based on inorganic materials. Many processing steps are required and can lead to long fabrication time and low yield.Polymer materials offer many distinct properties compared to inorganic materials, such as ease of fabrication, low production costs, simple processing steps, and compatibility with micro-fabrication technologies. ...