Na+ independent binding of [3H] muscimol to a membrane fraction of the brains of normal and dwarf mice

Although their body weights were decreased by about 77% and their brain weights by about 30%, high-affinity [3H] muscimol binding to a cerebral membrane fraction was not altered in hereditary pituitary dwarf mice. Marked changes in the level of pituitary growth-associated hormones do not appear to be associated with a change in cerebral GABA-receptors.     

Binding of [3H]GABA and [3H]muscimol to subcellular particles of a neurone-enriched culture of mouse brain

Summary Binding of [³H]GABA and [³H]muscimol, indicative of GABA-receptors, has been demonstrated in a neurone-enriched culture of embryonic mouse brain using a ligand-binding technique. Evidence is provided for the existence of different populations of GABA-receptors.This study was supported by C.N.R.S., ATP N^o 3356 and by Commissariat à l'Energie Atomique, Departement of Biologie. Thanks are due to Mlle Marie-Anne Frenkel for her excellent technical assistance.     

Identification of catecholamines and serotonin in the notochords of chick embryos]

The neurotransmitter amines, norepinephrine, dopamine and serotonine have been isolated from Chick notochords. Cholinergic agents produce important modifications in the amount of these amines and of one of their metabolites. The results demonstrate the presence, at a very early stage of development, between the second and the third day of incubation, of biogenic amines and cholinergic receptors.