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971.
灯盏乙素对大鼠肝线粒体氧化损伤的抑制作用 总被引:5,自引:0,他引:5
运用Fe^2 -Vc损伤体系诱导大鼠肝线粒体氧化损伤,并研究了灯盏乙素的抑制作用,采用分光光度法测定脂质过氧化物丙二醛(MDA)含量,膜蛋白巯基含量及线粒体肿胀度,利用荧光染料Rhodamine123对线粒体进行标记,跟踪线粒体膜电位的变化,研究发现20-50μmol/L的灯盏乙素能抑制MDA的生成并促使膜巯基含量下降,对线粒体肿胀和膜电位的降低都有一定的抑制作用,并呈剂量依赖关系,结果表明灯盏乙素是一种有效的抗氧化剂,能抑制活性氧诱导的线粒体氧化损伤。μ 相似文献
972.
973.
Climate-driven trends in contemporary ocean productivity 总被引:6,自引:0,他引:6
Behrenfeld MJ O'Malley RT Siegel DA McClain CR Sarmiento JL Feldman GC Milligan AJ Falkowski PG Letelier RM Boss ES 《Nature》2006,444(7120):752-755
Contributing roughly half of the biosphere's net primary production (NPP), photosynthesis by oceanic phytoplankton is a vital link in the cycling of carbon between living and inorganic stocks. Each day, more than a hundred million tons of carbon in the form of CO2 are fixed into organic material by these ubiquitous, microscopic plants of the upper ocean, and each day a similar amount of organic carbon is transferred into marine ecosystems by sinking and grazing. The distribution of phytoplankton biomass and NPP is defined by the availability of light and nutrients (nitrogen, phosphate, iron). These growth-limiting factors are in turn regulated by physical processes of ocean circulation, mixed-layer dynamics, upwelling, atmospheric dust deposition, and the solar cycle. Satellite measurements of ocean colour provide a means of quantifying ocean productivity on a global scale and linking its variability to environmental factors. Here we describe global ocean NPP changes detected from space over the past decade. The period is dominated by an initial increase in NPP of 1,930 teragrams of carbon a year (Tg C yr(-1)), followed by a prolonged decrease averaging 190 Tg C yr(-1). These trends are driven by changes occurring in the expansive stratified low-latitude oceans and are tightly coupled to coincident climate variability. This link between the physical environment and ocean biology functions through changes in upper-ocean temperature and stratification, which influence the availability of nutrients for phytoplankton growth. The observed reductions in ocean productivity during the recent post-1999 warming period provide insight on how future climate change can alter marine food webs. 相似文献
974.
在H263ZI‘MN8的控制技术基础上,提出可控的前后景码率分配算法、前景区优先编码策略以及优化的量化编码次序.可以仅使用一个控制参数来控制前后景的码率分配,并且编码后码流仍符合标准I-t263码流.试验结果表明,该算法在低比特率的情况下视频图像的主观质量要优于TMN8,非常适合窄信道视频通信的应用. 相似文献
975.
Membrane protein oligomeric structure and transport function 总被引:16,自引:0,他引:16
M Klingenberg 《Nature》1981,290(5806):449-454
Proteins which traverse membranes tend to have a dimeric structure in which the dimer is arranged asymmetrically across the membrane with the axis of symmetry perpendicular to the membrane plane. This general structure is well suited to the function of transporting nutrients across the cell membrane. 相似文献
976.
基于互联网的过程控制系统的安全性设计 总被引:2,自引:2,他引:2
分析了远程控制系统安全性设计要解决的两个方面问题:为防止未授权用户恶意破坏控制系统,提出了对付网络入侵者恶意操作控制系统的安全措施;为保证实时数据传输的快速性和安全性,将高级数据加密标准AES与网络通信加密协议SSL相结合,实现了适合于实时控制系统的数据加密算法,并通过测量实时数据加密传输的网络时延来验证该算法的有效性. 相似文献
977.
Lili Tian Jiyang Wang Jingqian Wei Henfu Pan Qingcai Guan Xiaobo Hu Yaogang Liu C. Q. Wang Y. T. Chow 《科学通报(英文版)》1998,43(23):1973-1973
The optical properties of Nd x Gd 1-x Al\-3(BO\-3)\-4 (NGAB) crystal are reported. The refractive index of it were mesured by V_prism method. The absorption spectra and the flourescence specra of NGAB were also obtained. The optical parameters of NGAB were calculated following J_O theory, the three optical parameters are Ω 2 =1 805×10 -20 , Ω 4=1 85×10 -20 , Ω 6=3 793×10 -20 (RMS=1 4×10 -7 ) and β c( 4F 3/2 → 4I 11/2 ) is about 0 53. 相似文献
978.
根据准噶尔盆地南缘地质构造特征和相似理论 ,成功地设计并进行了两组实验 :①利用砂箱模拟了该区剖面中可见的三排背斜带以及背斜紧闭、向斜开阔的特征 ;②利用湿粘土模拟了南缘几排背斜带与边界断裂斜交成“入”字型的平面特征 ,对西南缘存在东、西分段性的形成机制给予了很好的解释。模拟实验结果表明 ,压扭性走滑作用可以产生准噶尔盆地南缘的复杂构造现象 ,在右行压扭的区域动力学背景下可以产生与主位移带呈高角度斜交的张扭性断裂 ,以此可以解释南缘地区东、西分带的原因 相似文献
979.
1 Results The enantioselective addition of allylic organometallic reagents to aldehydes is a fundamental tool in organic synthesis.The high degree of both diastereo-and enantioselectivity gives the possibility to obtain a wide series of homoallylic alcohols,versatile intermediates in a great number of synthesis[1]. One of the most successful approaches is related to the discovery that organocatalytic activation of the nucleophilic allyltrichlorosilanes by means of neutral Lewis bases,such as formamides,... 相似文献
980.
Myeloid leukaemia inhibitory factor maintains the developmental potential of embryonic stem cells 总被引:102,自引:0,他引:102
R L Williams D J Hilton S Pease T A Willson C L Stewart D P Gearing E F Wagner D Metcalf N A Nicola N M Gough 《Nature》1988,336(6200):684-687
Embryonic stem (ES) cells, the totipotent outgrowths of blastocysts, can be cultured and manipulated in vitro and then returned to the embryonic environment where they develop normally and can contribute to all cell lineages. Maintenance of the stem-cell phenotype in vitro requires the presence of a feeder layer of fibroblasts or of a soluble factor, differentiation inhibitory activity (DIA) produced by a number of sources; in the absence of DIA the ES cells differentiate into a wide variety of cell types. We recently noted several similarities between partially purified DIA and a haemopoietic regulator, myeloid leukaemia inhibitory factor (LIF), a molecule which induces differentiation in M1 myeloid leukaemic cells and which we have recently purified, cloned and characterized. We demonstrate here that purified, recombinant LIF can substitute for DIA in the maintenance of totipotent ES cell lines that retain the potential to form chimaeric mice. 相似文献