Desensitization of adrenal tumor cells Y1 by ACTH and dibutyryl cyclic AMP]

The steroidogenic responsiveness of mouse adrenal tumor cell line (Y-1) to ACTH and db cAMP declines after stimulations by these compounds. The desensitization induced by ACTH appears early and is more pronounced than that induced by db cAMP. After removal of the hormone or the nucleotide, the recovery of cell responsiveness to both stimuli isprogressively restored. Full responsiveness is recovered within 24 hrs.     

X-ray diffraction of the collagen contained in blood vessels]

An X-ray diffraction study has been undertaken on Human and Rabbit blood-vessels. Vessels are stretched 500% and the diagrams present a great analogy with those obtained from collagen. Thus, it appears, that it is possible to determine by X-Rays some pathological anomalies of the collagen in vessels.     

Il succinato ed il fumarato quali regolatori dei sistemi enzimatici ossidasici dei grassi. Nota V

Résumé Dans le foie de cobaye, l'activité du système enzymatique oxydasique des acides gras est renforcée par une faible oxydation des acides succiniques et fumariques, tandis qu'elle est inhibée par une oxydation élevée. Il s'agit, peut-être, d'une concurrence pour l'ADP ou bien pour les transporteurs d'hydrogène.