全文获取类型
收费全文 | 51921篇 |
免费 | 252篇 |
国内免费 | 373篇 |
专业分类
系统科学 | 389篇 |
丛书文集 | 919篇 |
教育与普及 | 140篇 |
理论与方法论 | 228篇 |
现状及发展 | 22740篇 |
研究方法 | 1931篇 |
综合类 | 25389篇 |
自然研究 | 810篇 |
出版年
2013年 | 472篇 |
2012年 | 796篇 |
2011年 | 1597篇 |
2010年 | 412篇 |
2009年 | 339篇 |
2008年 | 979篇 |
2007年 | 1114篇 |
2006年 | 1062篇 |
2005年 | 1060篇 |
2004年 | 1118篇 |
2003年 | 921篇 |
2002年 | 973篇 |
2001年 | 1464篇 |
2000年 | 1417篇 |
1999年 | 1131篇 |
1996年 | 363篇 |
1992年 | 991篇 |
1991年 | 750篇 |
1990年 | 816篇 |
1989年 | 822篇 |
1988年 | 763篇 |
1987年 | 823篇 |
1986年 | 791篇 |
1985年 | 972篇 |
1984年 | 741篇 |
1983年 | 596篇 |
1982年 | 556篇 |
1981年 | 584篇 |
1980年 | 717篇 |
1979年 | 1522篇 |
1978年 | 1262篇 |
1977年 | 1215篇 |
1976年 | 972篇 |
1975年 | 997篇 |
1974年 | 1425篇 |
1973年 | 1240篇 |
1972年 | 1298篇 |
1971年 | 1423篇 |
1970年 | 1874篇 |
1969年 | 1497篇 |
1968年 | 1394篇 |
1967年 | 1395篇 |
1966年 | 1240篇 |
1965年 | 890篇 |
1959年 | 476篇 |
1958年 | 852篇 |
1957年 | 603篇 |
1956年 | 491篇 |
1955年 | 457篇 |
1954年 | 499篇 |
排序方式: 共有10000条查询结果,搜索用时 437 毫秒
101.
史济群 《华中科技大学学报(自然科学版)》1994,(3)
报道一种新颖的激光开槽、埋槽电极硅太阳电池的结构、工艺流程及其研制结果。在AM1.5,25℃,100mW/cm2的条件下,以面积为45cm3的36片硅片研制的硅太阳电池的输出参数的平均值为JSC=36.1mA/cm2,V∞=633mV,F.F.=0.798,η=18.23%,最后分析了种高性能硅太阳电池的设计特点。 相似文献
102.
Development and function of T cells in mice rendered interleukin-2 deficient by gene targeting. 总被引:69,自引:0,他引:69
Interleukin-2 (IL-2) is a lymphocytotropic hormone which is thought to have a key role in the immune response of mammalian cells. It is produced by a subpopulation of activated T-lymphocytes and acts in vitro as the principal auto- and paracrine T-cell growth factor (for reviews see refs 1-3). IL-2 is, however, not the sole T-cell growth factor, nor does it act exclusively on T cells, also promoting growth of NK cells and differentiation of B cells. A role for IL-2 in T-cell development has been postulated but remains controversial. Here we test the requirement for IL-2 in vivo using IL-2-deficient mice generated by targeted recombination. We find that mice homozygous for the IL-2 gene mutation are normal with regard to thymocyte and peripheral T-cell subset composition, but that a dysregulation of the immune system is manifested by reduced polyclonal in vitro T-cell responses and by dramatic changes in the isotype levels of serum immunoglobulins. 相似文献
103.
M. Ishibashi M. Tsuda Y. Ohizumi T. Sasaki J. Kobayashi 《Cellular and molecular life sciences : CMLS》1991,47(3):299-300
Summary A new bromotyrosine-derived alkaloid with antileukemic activity, purealidin A (5), has been isolated from the Okinawan marine spongePsammaplysilla purea and its chemical structure elucidated on the basis of the spectroscopic data. 相似文献
104.
人性假设与企业人力资源管理 总被引:5,自引:0,他引:5
人性假设是许多社会科学领域研究的出发点 ,企业也常常从自己的人性假设出发形成企业人力资源管理的理念。基于不同的人性假设 ,中国古代哲学、近现代西方经济学和管理学分别提出了对社会治理和企业治理的看法。在总结与分析的基础上 ,我们提出一种“混沌人”的假设。 相似文献
105.
106.
萃取浮选光度法测定微量钼的研究及应用 总被引:2,自引:0,他引:2
研究了用甲苯萃取浮选Mo(Ⅴ)—SCN~-—Kφ三元络合物的各种条件。在硫酸介质中,紫红色络合物最大吸收波长位于585nm,摩尔吸光系数为2.8×10~5l·mol~(-1)·cm~(-1),钼量在0—10μg/25ml范围内符合比耳定律。大量常见元素均不干扰,40倍的钨(Ⅵ)亦不干扰钼的测定,方法已应用于钨矿中微量钼的测定,其结果令人满意。 相似文献
107.
M E MacDonald A Novelletto C Lin D Tagle G Barnes G Bates S Taylor B Allitto M Altherr R Myers 《Nature genetics》1992,1(2):99-103
Analysis of 78 Huntington's disease (HD) chromosomes with multi-allele markers revealed 26 different haplotypes, suggesting a variety of independent HD mutations. The most frequent haplotype, accounting for about one third of disease chromosomes, suggests that the disease gene is between D4S182 and D4S180. However, the paucity of an expected class of chromosomes that can be related to this major haplotype by assuming single crossovers may reflect the operation of other mechanisms in creating haplotype diversity. Some of these mechanisms sustain alternative scenarios that do not require a multiple mutational origin for HD and/or its positioning between D4S182 and D4S180. 相似文献
108.
Ramsés Fuenmayor 《Systemic Practice and Action Research》1991,4(5):473-490
Both an ontoepistemology for reductionist modern science (counter-ontoepistemology) and an ontology for interpretive Systemology have been outlined in the two preceding papers in this special issue ofSystems Practice. In the present article, the notion of “truth” is interpreted in terms of both the ontoepistemology of “reductionism” and the ontology of interpretive systemology. Both interpretations are discussed. Such a discussion represents the objective of this paper, that is, to outline the epistemological “face” of the ontoepistemology of interpretive systemology. In order to design that “epistemological face,” the relation between ontology and epistemology must be clarified. Such a relation is seen from the standpoint already provided by the ontology. After the discussion on the notion of truth, the general shape of a systemic-interpretive inquiring process is outlined. 相似文献
109.
Structure of the detoxification catalyst mercuric ion reductase from Bacillus sp. strain RC607 总被引:10,自引:0,他引:10
Several hundred million tons of toxic mercurials are dispersed in the biosphere. Microbes can detoxify organo-mercurials and mercury salts through sequential action of two enzymes, organomercury lyase and mercuric ion reductase (MerA). The latter, a homodimer with homology to the FAD-dependent disulphide oxidoreductases, catalyses the reaction NADPH + Hg(II)----NADP+ + H+ + Hg(0), one of the very rare enzymic reactions with metal substrates. Human glutathione reductase serves as a reference molecule for FAD-dependent disulphide reductases and between its primary structure and that of MerA from Tn501 (Pseudomonas), Tn21 (Shigella), p1258 (Staphylococcus) and Bacillus, 25-30% of the residues have been conserved. All MerAs have a C-terminal extension about 15 residues long but have very varied N termini. Although the enzyme from Streptomyces lividans has no addition, from Pseudomonas aeruginosa Tn501 and Bacillus sp. strain RC607 it has one and two copies respectively of a domain of 80-85 residues, highly homologous to MerP, the periplasmic component of proteins encoded by the mer operon. These domains can be proteolytically cleaved off without changing the catalytic efficiency. We report here the crystal structure of MerA from the Gram-positive bacterium Bacillus sp. strain RC607. Analysis of its complexes with nicotinamide dinucleotide substrates and the inhibitor Cd(II) reveals how limited structural changes enable an enzyme to accept as substrate what used to be a dangerous inhibitor. Knowledge of the mode of mercury ligation is a prerequisite for understanding this unique detoxification mechanism. 相似文献