有序介孔氧化硅材料中的药物分子 组装及缓释研究进展

伴随经济全球化和知识经济的到来,传统的刚性管理模式严重制约着企业人力资源的创新性和主动性,企业人力资源只有实施柔性管理才能适应当今的竞争环境。介绍了人力资源柔性管理的定义、国内外学者在这一领域的研究状况及启示。国内外的柔性管理研究成果丰富,具有一定的广度和深度,但还存在不足。未来研究不仅要进行定性研究,更要进行定量分析;不仅要发展和丰富理论知识,更要将这些理论应用到实际发生的人力资源柔性管理的案例中,对其进行详细描述、解释,以找出可以用来指导企业实践的规律性东西,建立起科学的理论体系,从而进一步丰富和发展企业中的人力资源柔性管理理论。     

“装箱问题的一种新的近似算法”的一个注记

一维装箱问题(Bin-Packing)是一个著名的NP难的组合问题,具有极其广泛的应用背景,受到了深入细致的研究,取得了许多好的成果.2004年孙春玲等1对一维装箱问题给出一个新的近似算法,称作交叉算法,证明该算法达到一维装箱问题的最好的近似值3/2.       

《云南大学学报(自然科学版)》编委风采

李永昆,男,博士。云南大学数学与统计学院教授、副院长、博士生导师、中国数学会理事、云南省数学会副理事长。2002年11月被云南省人民政府授予云南省中青年学术和技术带头人称号。先后主持完成过国家自然科学基金2项,云南省自然科学基金4项。2004年获“宝钢优秀教师奖”。2005年获云南省自然科学二等奖。已发表学术论文110余篇,其中40余篇被SCl收录,并被SCI引用350余次。       

细推物理须行乐——记世界物理年4位中科院院士到云南大学讲学访问

为纪念世界物理年,受云南大学邀请,2005年3月21日～30日,中国科学院郝柏林、孙义燧、李家明、葛墨林4位院士对云南大学进行了访问.21日4位院士先与云南大学非线性复杂系统中心的师生们进行了座谈,随后郝柏林院士和李家明院士在云南大学科学馆分别做了“Finding Genesin the Rice Genome”和“基础研究的乐趣”两场报告.郝柏林院士还于29日下午做了“数字文明:物理学和计算机”的报告.院士们的报告精彩生动,引人入胜,不时赢得台下热烈的掌声.报告结束后大家争相提问,院士们耐心细致地分别作了回答.郝柏林院士和李家明院士等大师们渊博的知识严谨的治学作风,谦虚的品格给在场的老师和同学们留下了深刻的印象.       

Deciphering the BAR code of membrane modulators

The BAR domain is the eponymous domain of the “BAR-domain protein superfamily”, a large and diverse set of mostly multi-domain proteins that play eminent roles at the membrane cytoskeleton interface. BAR domain homodimers are the functional units that peripherally associate with lipid membranes and are involved in membrane sculpting activities. Differences in their intrinsic curvatures and lipid-binding properties account for a large variety in membrane modulating properties. Membrane activities of BAR domains are further modified and regulated by intramolecular or inter-subunit domains, by intermolecular protein interactions, and by posttranslational modifications. Rather than providing detailed cell biological information on single members of this superfamily, this review focuses on biochemical, biophysical, and structural aspects and on recent findings that paradigmatically promote our understanding of processes driven and modulated by BAR domains.     

打造团队精神 提高企业执行力

在企业飞速发展的时代,执行力对一个企业的发展起着越来越重要的作用,它将是构成企业竞争力的重要组成部分,从而成为决定企业成败的一个重要因素。     

皮秒Nd:YAG激光对生物金属纯Ti和Ti–13Nb–13Zr合金的表面改性

The effects of picosecond Nd:YAG laser irradiation on chemical and morphological surface characteristics of the commercially pure titanium and Ti–13Nb–13Zr alloy in air and argon atmospheres were studied under different laser output energy values. During the interaction of laser irradiation with the investigated materials, a part of the energy was absorbed on the target surface, influencing surface modifications. Laser beam interaction with the target surface resulted in various morphological alterations, resulting in crater formation and the presence of microcracks and hydrodynamic structures. Moreover, different chemical changes were induced on the target materials’ surfaces, resulting in the titanium oxide formation in the irradiation-affected area and consequently increasing the irradiation energy absorption. Given the high energy absorption at the site of interaction, the dimensions of the surface damaged area increased. Consequently, surface roughness increased. The appearance of surface oxides also led to the increased material hardness in the surface-modified area. Observed chemical and morphological changes were pronounced after laser irradiation of the Ti–13Nb–13Zr alloy surface.     

5-(Hydroxyimino)-4-methoxy-2-(pivaloylimino)thiazolidine-3-acetamide,a reduced nitroheterocyclic derivative with potent schistosomicidal properties

Summary The synthesis and antischistosome properties of 5-(hydroxyimino)-4-methoxy-2-(pivaloylimino)thiazolidine-3-acetamide (1) are described. The compound was prepared by reduction of the nitrothiazoline (2) with stannous chloride in methanol, and represents the first example of a reduced nitroheterocyclic compound showing potent schistosomicidal properties. The possible relationship of compounds such as1 to the as yet unidentified reduced active but toxic entities formed in vivo from nitroheterocyclics like metronidazole is discussed.Acknowledgments. The authors are grateful to Dr A. J. Everett and his staff for the physical chemistry measurements, and to Mr G. Dickerson for the antischistosome testing.     

嵌段聚醚酯化物的结构分析

本文对合成的嵌段聚醚酯化物的分子结构做了红外、高压液相色谱和~(13)C核磁共振分析,得出其构象和各种原子连接的方式,这些特征图谱为研究和生产此类型表面活性剂提供了可靠的检测依据。