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911.
912.
913.
The lambda immunoglobulin light chain (Ig lambda) locus of BALB/c inbred mice consists of two variable region gene segments (V lambda)1-3, and four constant region gene segments (C lambda)1,2,4,5. Each C lambda gene segment is associated with a unique joining segment (J lambda)2,4-7, and they are organized in two paired units, J3C3-J1C1 and J2C2-J4C4 (refs 4, 8). Using cDNA probes specific for C lambda 1 and C lambda 2 (ref. 9) we have analysed the genomic organization of the C lambda gene segments in wild-derived and inbred strains of mice. Although Southern blots of the genomic DNA of inbred mice show a constant pattern of hybridization, wild-derived mice show a high degree of variation in the number, size and intensity of hybridizing fragments. We have now found that, per haploid genome, mice of a Mus musculus musculus stock isolated from Sladeckovce, Czechoslovakia (CzII) have at least 12 C lambda segments, and mice of a Mus musculus domesticus stock 'Centreville Lights' from Centreville, Maryland (CL) have at least 8 C lambda segments. There appears to have been relatively recent amplifications of the C lambda gene segments in wild mice. 相似文献
914.
P. Glikman A. Gutnisky M. F. Gimeno A. L. Gimeno 《Cellular and molecular life sciences : CMLS》1981,37(6):589-590
Summary The in vivo administration of59Fe to the rat accompanied by acetylsalicylic acid (ASA) enhanced significantly counts in blood, spleen, liver and femur without affecting those of the intestine. The results suggest that ASA augments iron absorption either via an inhibitory action on the synthesis of prostaglandins or by a purely chemical mechanism.This work was supported by Grant No. 6638 from CONICET (Argentina).The technical assistance of Mrs María E. Castro and Mrs Patricia Dubra is gratefully acknowledged. 相似文献
915.
916.
Early removal of the optic cup of the chick embryo prevents innervation of the contralateral optic lobe. This reduces the rate of development od citrate synthetase. The posthatch increase of the level of this enzyme related to oxidative metabolism is not impaired by denervation of the chick optic lobe. 相似文献
917.
C. L. Kaul P. K. Talwalker R. S. Grewal 《Cellular and molecular life sciences : CMLS》1976,32(8):1072-1074
Summary The sympathetic nervous system in the rat does not play any significant role in the streptozotocin-induced and tolbutamipe-induced hypoglycemia. 相似文献
918.
919.
The control of contraction activation by the membrane potential 总被引:2,自引:0,他引:2
C. Caputo G. Gottschalk H. -Ch. Lüttgau 《Cellular and molecular life sciences : CMLS》1981,37(6):580-581
Summary Force measurements under voltage-clamp control were performed in short toe muscles of the frog. The results show a) that the activation of force development and its repriming process can at least qualitatively be correlated to charge movement kinetics; b) that caffeine improves EC coupling by potentiating the potential dependent activation process.This work was supported by DFG (SFB 114 Bionach) and DAAD. 相似文献
920.