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91.
M. Rizzardini A. Ferraroli D. Dal Fiume L. Cantoni 《Cellular and molecular life sciences : CMLS》1984,40(12):1390-1392
Summary Im male rats hepatic cytochromes b5 and P-450 were reduced at different times after treatment with cyclophosphamide (CP) (200 mg/kg i.p. for 3 days). In contrast, microsomal heme did not change until 48 h after the last dose of CP, leading to accumulation of heme in a non-cytochromal form. Parallel to the above changes the heme metabolism showed derangement: -aminolaevulinate synthase, the rate-limiting enzyme in heme synthesis, was depressed and heme oxygenase, the enzyme which catalyzes the oxidative degradation of heme, was increased. 相似文献
92.
Summary In the rat, prolonged activation of 1-adrenoceptors causes a gain in salivary gland weight, whereas prolonged blockade of these receptors causes a reduction in weight.This work was supported by grants to J.E. from the Medical Faculty in Lund and the Swedish Medical Research Council (05927). 相似文献
93.
94.
Summary Resting oxygen consumption of the vascularly isolated gracilis anticus muscle of the rat perfused by natural circulation via the femoral artery with diluted or undiluted blood depends on oxygen delivery (the product of flow rate and arterial oxygen concentration-DO2) only when DO2 falls below 16 l/min/g. 相似文献
95.
F. V. DeFeudis L. M. Orensanz Muñoz M. A. Vidal G. Corrochano M. Sanchez del Alamo 《Cellular and molecular life sciences : CMLS》1978,34(9):1169-1170
Summary High-affinity, Na+-independent binding of -alanine to a synaptosomal fraction of rat brain was potently inhibited by glycine and by some other -amino acids, but not by taurine or GABA. This binding mechanism, which was also sensitive to both bicuculline and strychnine, might involve synaptic receptors for both -alanine and glycine.This study was supported in part by Centro Ramón y Cajal and Fundacion Juan March. 相似文献
96.
B. Stankiewicz-Choroszucha J. Górski 《Cellular and molecular life sciences : CMLS》1978,34(3):357-358
Summary It was shown in the rat that mobilization of intramuscular triglyceride during exercise is controlled by the adrenergic system.Acknowledgments. The work was supported by the Polish Academy of Sciences, grant No. 10.4.2.01.3.2. 相似文献
97.
Daily administration of vitamin D3 (75,000 IU/kg b. wt) for 7 days accelerated Trichinella spiralis cyst calcification in rats with a 14-week-old infection. When disodium ethane-1-hydroxy-1, 1-diphosphonate (EHDP) was administered (50 mg/kg b. wt) from 2 days before until 2 days after vitamin D3 treatment, cyst calcification was inhibited. Thus, the ability to inhibit E. spiralis calcification has demonstrated for the first time. 相似文献
98.
99.
The spontaneous conversion of mammalian cyclic GMP-dependent protein kinase (G-PK) into modulator-dependent protein kinase (type II) (M-PKII) in the absence of cGMP or histone was observed in vitro. The findings, together with similarity in substrate protein specificity, suggest that M-PKII is the catalytic subunit of mammalian G-PK. 相似文献
100.
At ambient temperatures (Ta) of both 8 and 22 degrees C, intraventricular administration of TRH (10-80 microgram) produced a dose-dependent hypothermia in rats. The hypothermia was due to both decreased metabolic heat production and cutaneous vasodilatation. In contrast, at 30 degrees C Ta, TRH increased metabolic heat production (due to behavioral excitation) and led to hyperthermia. 相似文献