Influence of pinealectomy on corticotropin (ACTH)

Sensory deprivation produced by removing the eyes and olfactory bulbs in male rats allowed pinealectomy to markedly augment the post-adrenalectomy elevation of ACTH levels. Pineal removal or sensory deprivation separately did not have this effect. Thus, intact sensory input and an intact pineal gland are independently capable of restricting the post-adrenalectomy rise in ACTH levels.     

Development and pathologies of the arterial wall

Arteries consist of an inner single layer of endothelial cells surrounded by layers of smooth muscle and an outer adventitia. The majority of vascular developmental studies focus on the construction of endothelial networks through the process of angiogenesis. Although many devastating vascular diseases involve abnormalities in components of the smooth muscle and adventitia (i.e., the vascular wall), the morphogenesis of these layers has received relatively less attention. Here, we briefly review key elements underlying endothelial layer formation and then focus on vascular wall development, specifically on smooth muscle cell origins and differentiation, patterning of the vascular wall, and the role of extracellular matrix and adventitial progenitor cells. Finally, we discuss select human diseases characterized by marked vascular wall abnormalities. We propose that continuing to apply approaches from developmental biology to the study of vascular disease will stimulate important advancements in elucidating disease mechanism and devising novel therapeutic strategies.     

Über einheitliche Racemate des 1-Oxo-2-methyl-7-methoxy-octahydrophenanthren-2-carbonsäuremethylesters

Summary The racemic mixture of 1-oxo-2-methyl-7-methoxy-octahydrophenanthrene-2-carboxylic acid methyl esters has been separated into three crystalline racemates.     

Reactions of Captan and Folpet with thiols

Zusammenfassung Es wird gezeigt, dass die Pflanzenschutzmittel Captan und Folpet mit Verbindungen, die Thiolgruppen enthalten, unter physiologischen Bedingungen (gepuffertes Blut) reagieren.

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This study was supported by Research Contract No. PH 43-64-57, National Cancer Institute, National Institutes of Health, Public Health Service, and represents Paper No. 33 of this Contract.     

The high activity of fluorohydroxybenzylbenzimidazoles against some small RNA-viruses

Zusammenfassung Fluorierte Derivate des 2-(-Oxybenzyl)-benzimidazol hemmen die Vermehrung des Poliovirus, 1, 2 und 3, sowie diejenige des Coxsackievirus A9 und A21.     

Genetic control of rye endosperm proteins

Résumé En comparant les diagrammes d'électrophorèse en gels d'amidon de gliadine obtenus à partir d'un blé hexaploïde, d'un seigle diploïde et de blé + seigle amphiploïdes avec les lignes d'additionnement des chromosomes blé-seigle on constata qu'un chromosome de seigle contrôle toutes les gliadines du seigle.