全文获取类型
收费全文 | 5460篇 |
免费 | 622篇 |
专业分类
系统科学 | 1073篇 |
理论与方法论 | 276篇 |
现状及发展 | 874篇 |
研究方法 | 13篇 |
综合类 | 3846篇 |
出版年
2018年 | 727篇 |
2017年 | 733篇 |
2016年 | 431篇 |
2015年 | 32篇 |
2014年 | 4篇 |
2013年 | 4篇 |
2012年 | 260篇 |
2011年 | 951篇 |
2010年 | 814篇 |
2009年 | 455篇 |
2008年 | 514篇 |
2007年 | 764篇 |
2006年 | 5篇 |
2005年 | 45篇 |
2004年 | 127篇 |
2003年 | 153篇 |
2002年 | 55篇 |
2000年 | 1篇 |
1999年 | 1篇 |
1994年 | 2篇 |
1991年 | 3篇 |
1967年 | 1篇 |
排序方式: 共有6082条查询结果,搜索用时 15 毫秒
91.
A major portion of the mammalian genome is transcribed to produce large numbers of noncoding RNAs(ncRNAs).During the past decade,the discovery of small RNAs,including the microRNAs(miRNA) and small interfering RNAs(siRNA),has led to important advances in biology.The breadth of the ncRNA field of study has substantially expanded and many recent results have revealed a range of functions that can be attributed to the miRNAs and other ncRNAs.For example,H19 RNA,HOTAIR RNA,transcribed ultraconserved regions(T-UCRs),natural antisense RNA,transfer RNA and mitochondrial noncoding RNA have been suggested to play important roles in cancers and other diseases as well as in diverse cellular processes.In this review,we focus on the current status of several classes of ncRNAs associated with cancer with the emphasis on those that are not microRNAs. 相似文献
92.
HE XiuBin XU Bei YUAN ZhiYun 《科学通报(英文版)》2007,52(4):504-511
C-isotope analysis of the carbonates in the Upper Neoproterozoic in Keping, Xinjiang indicates that the Qigebrak Formation and the Upper Sugaitbrak Formation mainly record positive C-isotope values, and a distinct positive excursion occurs in the lower part of the Qigebrak Formation. There are three negative excursions in the boundary between the Qigebrak Formation and the Cambrian, the uppermost and lowermost Upper Sugaitbrak Formation. These characters resemble those of the Upper Neoproterozoic in the Three-Gorge area, which suggests that the Upper Sugaitbrak Formation and Qigebrak Formation can be correlated with the middle and upper parts of the Doushantuo Formation and Dengying Formation, respectively. The negative excursion at the top of the Upper Sugaitbrak Formation corresponds to that at the top of the Doushantuo Formation, while the negative excursion at the bottom of the Sugaitbrak Formation can be correlated with that at the middle part of the Doushantuo Formation in the Three-Gorge area and that at the top of the Hangelchaok diamictites in the Quruqtagh area. 相似文献
93.
Ye Li 《科学通报(英文版)》2008,53(23):3615-3619
The photophysics of Zn(tetraphenylporphyrin,TPP), Zn(tetra-2,4,6-trimethylphenyl porphyrin, TMP), Zn (tetra-(o-dichlorophenyl) porphyrin, TPPCI8), Cu(tetraphenylporphyrin,TPP), Cu(tetra-2,4,6-trimethyl- phenyl porphyrin,TMP), and Cu(tetra-(o-dichlorophenyl) porphyrin, TPPCIE, TPPCI8) in several solvents have been investigated on steady state and time-resolved spectroscopy. The Cu(TPPCI8 ) is normal and shows no evidence of CT transition in the visible or near UV regions in nonpolar solvent. However, Cu(TPPCI8)shows a blue shift in the absorption spectrum and intramolecular CT bands at absorption spectra in polar solvent, which shows a fluorescence maximum emission at 650 nm and 8.4 ns lifetime. The reason can be attributed to two points. Firstly, the increase of solvent polarity can enlarge outer reorganisational energy, which is favorable to reduce the activation free energy of charger-transfer transition based on Marcus theory of electron transfer. Moreover, the internal heavy-atom effect on Cu(TPPCIE) is encouraging to stabilize the 2T1 state also, which increases the possibility of population to CT band from 2T1 state. This result is in accord with an earlier estimate of a 10 ns lifetime and CT absorption at 640 nm bands for the CT state of Cu (11) octethylporphyrins. Other possible reasons arousing unusual fluorescence like H-bonding, axial ligands, molecular aggregation are excluded. 相似文献
94.
Copper/liquid microcapsule composite coatings with polyvinyl alcohol (PVA), gelatin or methyl cellulose (MC) as shell materials were prepared by electrodeposition. The influence of shell materials on the corrosion resistance of the composite coatings in 0.1 M H2SO4 was investigated by means of electrochemical techniques, scanning electron microscopy (SEM), and energy dispersion spectrometry (EDS). The results show that the participation of microcapsules can enhance the corrosion resistance of the composite coatings compared with the traditional copper layer. Based on the analysis of electrochemical test results, the release ways of microcapsules were deduced. Gelatin and MC as the shell materials of microcapsules are easy to release quickly in the composite coating. On the contrary, the releasing speed of PVA microcapsules is relatively slow due to their characteristics. 相似文献
95.
PEI FuPing XU WenLiang YANG DeBin ZHAO QuanGuo LIU XiaoMing HU ZhaoChu 《科学通报(英文版)》2007,52(7):942-948
Zircon LA-ICP MS U-Pb dating of six metamorphic rocks and a metagranite (breccia) from southern basement of the Songliao Basin are reported in order to constrain the formation ages of basement. The basement metamorphic rocks in the Songliao Basin mainly consist of metagabbro (L45-1), amphibolite (SN117), metarhyolitical tuff (G190), sericite (Ser) schist (N103), chlorite (Chl) schist (T5-1), biotite (Bi)-actinolite (Act)-quartz (Q) schist (Y205), and metagranite (L44-1). The cathodoluminesence (CL) images of the zircons from metagabbro (L45-1) and metagranite (L44-1) indicate that they have cores of magmatic origin and rims of metamorphic overgrowths. Their U-Pb isotopic ages are 1808±21 Ma and 1873±13 Ma, respectively. The zircons with oscillatory zoning from amphibolite (SN117) and Chl schist (T5-1), being similar to those of mafic igneous rocks, yield ages of 274 ± 3.4 Ma and 264 ± 3.2 Ma, re-spectively. The zircons from metarhyolitical tuff (G190) and Ser schist (N103) display typical magmatic growth zoning and yield ages of 424 ± 4.5 Ma and 287 ± 5.1Ma, respectively. Most of zircons from Bi-Act-Q schist (Y205) are round in shape and different in absorption degree in the CL images, implying their sedimentary detritals. U-Pb dating yield concordant ages of 427 ± 3.1Ma, 455 ± 12 Ma, 696 ± 13 Ma, 1384±62 Ma, 1649±36 Ma, 1778±18 Ma, 2450±9 Ma, 2579±10 Ma, 2793±4 Ma and 2953±14 Ma. The above-mentioned results indicate that the Precambrian crystalline basement (1808―1873 Ma) exists in the southern Songliao Basin and could be related to tectonic thrust, and that the Early Paleozoic (424―490 Ma) and Late Paleozoic magmatisms (264―292 Ma) also occur in the basin basement, which are consistent with the ages of the detrital zircons from Bi-Act-Q schist in the basement. 相似文献
96.
LEI WanHua LIU HuiXue ZHONG LiJun YANG XiaoDa WANG Kui 《科学通报(英文版)》2007,52(20):2775-2781
Several vanadium compounds have been known for the hypoglycemic and anticancer effects. However, the mechanisms of the pharmacological and toxicological effects were not clear. In this work, we in- vestigated the potential targets of vanadium in mitochondria. Vanadyl ions were found to bind to mi- tochondria from rat liver with a stoichiometry of 244±58 nmol/mg protein and an apparent dissocia- tion constant (Kd) of (2.0±0.8)×10·16 mol/L. Using size exclusion chromatography, a vanadium-binding protein was isolated and identified to be the 60-kDa heat shock protein (HSP60) by mass spectrometry analysis and immunoassays. Additionally, binding of vanadyl ions was found to result in depolymeri- zation of homo-oligomeric HSP60 (GroEL). HSP60 is an indispensable molecular chaperone and in- volved in many kinds of pathogenesis of inflammatory and autoimmune diseases, e.g. type 1 diabetes. Our results suggested that HSP60 could be a novel important target involved in the biological and/or toxicological effects of vanadium compounds. 相似文献
97.
This paper is an extension of the application of neighborhood interference model--being modified--to the study of the interference between forest plants and herbaceous plants. The exploration of the neighborhood interference between triploid Populus tomentosa and Lolium multiflorum shows that the interference of Lolium multiflorum on triploid populus tomentosa is positive, with the primary interference factor living weight, and secondary factor cover degree; the growth of an individual tree is affected by the number, height, and coverage of the Lolium multiflorum; the more dense the coverage of the Lolium multiflorum in a certain area, the taller, faster and more trees will grow as a result of a greater positive neighborhood interference. The modified neighborhood interference model well serves as an effective approach to extend the application of neighborhood interference researches. 相似文献
98.
Evaluation of flotation behavior, solution measurements, and surface analyses were performed to investigate the effects of chloride ion addition on the sulfidization of cerussite in this study. Micro-flotation tests indicate that the addition of chloride ions prior to sulfidization can significantly increase the flotation recovery of cerussite, which is attributed to the formation of more lead sulfide species on the mineral surface. Solution measurement results suggest that the addition of chloride ions prior to sulfidization induces the transformation of more sulfide ions from pulp solution onto the mineral surface by the formation of more lead sulfide species. X-ray diffraction and energy-dispersive spectroscopy indicate that more lead sulfide species form on the mineral surface when chloride ions are added prior to sulfidization. These results demonstrate that the addition of chloride ions prior to sulfidization can significantly improve the sulfidization of cerussite, thereby enhancing the flotation performance. 相似文献
99.
Lei Xie RuCheng Wang Jun Chen JinChu Zhu WenLan Zhang DeZi Wang APeng Yu 《科学通报(英文版)》2009,54(5):798-805
The Qitianling calc-alkaline granite in Hunan Province (South China) has attracted much attention since the discovery of the
Furong super-large tin deposit. The present study provides new mineralogical data to address their implications for exploration
of tin deposits. In the Taoxiwo granite in the southeastern part of the Qitianling granite body, Sn-rich titanite was identified
as an important type of Sn-bearing mineral. The titanite commonly occurs with biotite as euhedral crystals, exhibiting typical
envelope-like shape and sector-zoning texture. These indicate that the titanite most likely crystallized in the magmatic stage.
Electron-microprobe analyses show that the titanite is enriched in tin up to 1.12 wt% SnO2, with an average of 0.43 wt%. With the crystallization of the granite, primary minerals undertook hydrothermal alteration
by magma-derived fluids. Subsequently, in the hydrothermal stage, the primary Sn-bearing titanite was altered (at least partially),
but still preserved its typical envelope-shaped outline. Micro-scale cassiterite is a representative product of such alteration;
other secondary minerals include fluorite, ilmenite, Sn-bearing rutile and quartz. Therefore, the titanite, commonly present
in the calcalkaline granites, can be treated as an important Sn-carrying mineral in the Qitianling granite, reflecting the
primary magmatic environment with tin enrichment. The hydrothermal alteration of the primary titanite and subsequent crystallization
of cassiterite recorded a process of leaching and accumulation of tin in magmatic-hydrothermal evolution of the Sn-bearing
granite. Thus, this titanite has important implications for tin exploration.
Supported by National Natural Science Foundation of China (Grant Nos. 40730423 and 40221301) and Project of China Geological
Survey (Grant No. 1212010632100) 相似文献
100.
Development of a middle and low latitude theoretical ionospheric model and an observation system data assimilation experiment 总被引:3,自引:0,他引:3
On the basis of previous work, we develop a middle and low latitude theoretical ionospheric model in this paper, named Theoretical Ionospheric Model of the Earth in the Institute of Geology and Geophysics, Chinese Academy of Sciences (TIME-IGGCAS). TIME-IGGCAS solves the equations of mass continuity, motion and energy of electron and ions self-consistently and uses an eccentric dipole field approximation to the Earth's magnetic field. We combine the Eulerian and Lagrangian approaches in the model and take account of the plasma ExB drift velocity. Calculation results reveal that the model is steady and credible and can reproduce most large-scale features of ionosphere. By using TIME-IGGCAS, we carried out an observation system data assimilation experiment. Assimilation results show that the ExB drift velocity can be accurately estimated by ingesting the observed foF2 and hmF2 into the model applying nonlinear least-square fit method. We suggest that this work is of great significance in the development of ionospheric data assimilation model to give better nowcast and forecast of ionosphere. 相似文献