全文获取类型
收费全文 | 2012篇 |
免费 | 18篇 |
国内免费 | 2篇 |
专业分类
系统科学 | 51篇 |
理论与方法论 | 25篇 |
现状及发展 | 1360篇 |
研究方法 | 80篇 |
综合类 | 442篇 |
自然研究 | 74篇 |
出版年
2020年 | 15篇 |
2018年 | 35篇 |
2017年 | 29篇 |
2016年 | 37篇 |
2015年 | 31篇 |
2014年 | 16篇 |
2013年 | 27篇 |
2012年 | 57篇 |
2011年 | 90篇 |
2010年 | 27篇 |
2009年 | 16篇 |
2008年 | 43篇 |
2007年 | 40篇 |
2006年 | 57篇 |
2005年 | 53篇 |
2004年 | 39篇 |
2003年 | 48篇 |
2002年 | 44篇 |
2001年 | 31篇 |
2000年 | 16篇 |
1999年 | 19篇 |
1992年 | 19篇 |
1991年 | 17篇 |
1985年 | 15篇 |
1984年 | 28篇 |
1983年 | 16篇 |
1982年 | 21篇 |
1981年 | 25篇 |
1979年 | 42篇 |
1978年 | 39篇 |
1977年 | 46篇 |
1976年 | 39篇 |
1975年 | 35篇 |
1974年 | 40篇 |
1973年 | 50篇 |
1972年 | 46篇 |
1971年 | 42篇 |
1970年 | 69篇 |
1969年 | 67篇 |
1968年 | 93篇 |
1967年 | 70篇 |
1966年 | 57篇 |
1965年 | 55篇 |
1964年 | 49篇 |
1963年 | 22篇 |
1962年 | 28篇 |
1961年 | 20篇 |
1960年 | 15篇 |
1959年 | 18篇 |
1958年 | 14篇 |
排序方式: 共有2032条查询结果,搜索用时 390 毫秒
941.
942.
943.
944.
Aging alters resynchronization of the circadian system in rats after a shift of the light-dark cycle
Summary Four days following an 8-h advance of the light-dark cycle, the circadian rhythms in the pineal N-acetyltransferase activity and melatonin content reappeared in 7-week-old rats, but were still abolished in 24-month-old animals. 相似文献
945.
Darío Acuña-Castroviejo Ibtissem Rahim Carlos Acuña-Fernández Marisol Fernández-Ortiz Jorge Solera-Marín Ramy K. A. Sayed María E. Díaz-Casado Iryna Rusanova Luis C. López Germaine Escames 《Cellular and molecular life sciences : CMLS》2017,74(21):3965-3987
After the characterization of the central pacemaker in the suprachiasmatic nucleus, the expression of clock genes was identified in several peripheral tissues including the immune system. The hierarchical control from the central clock to peripheral clocks extends to other functions including endocrine, metabolic, immune, and mitochondrial responses. Increasing evidence links the disruption of the clock genes expression with multiple diseases and aging. Chronodisruption is associated with alterations of the immune system, immunosenescence, impairment of energy metabolism, and reduction of pineal and extrapineal melatonin production. Regarding sepsis, a condition coursing with an exaggerated response of innate immunity, experimental and clinical data showed an alteration of circadian rhythms that reflects the loss of the normal oscillation of the clock. Moreover, recent data point to that some mediators of the immune system affects the normal function of the clock. Under specific conditions, this control disappears reactivating the immune response. So, it seems that clock gene disruption favors the innate immune response, which in turn induces the expression of proinflammatory mediators, causing a further alteration of the clock. Here, the clock control of the mitochondrial function turns off, leading to a bioenergetic decay and formation of reactive oxygen species that, in turn, activate the inflammasome. This arm of the innate immunity is responsible for the huge increase of interleukin-1β and entrance into a vicious cycle that could lead to the death of the patient. The broken clock is recovered by melatonin administration, that is accompanied by the normalization of the innate immunity and mitochondrial homeostasis. Thus, this review emphasizes the connection between clock genes, innate immunity and mitochondria in health and sepsis, and the role of melatonin to maintain clock homeostasis. 相似文献
946.
Arielson dos Santos Protázio Ralph Lacerda Albuquerque Laura Martini Falkenberg 《Journal of Natural History》2015,49(15-16):957-976
Differences in advertisement calls and calling sites are important mechanisms that regulate interactions in anuran assemblages. Individuals might have preferences for ranges of acoustic parameters and calling sites that reduce overlap and ensure coexistence. Herein, acoustic and ecological data were used to investigate the relationships among 12 anurans that co-occur in temporary ponds in the Caatinga, Cabaceiras municipality, Paraíba state, Brazil. Anurans exhibited calling activity correlated with rainfall, but were also spatially dispersed. High overlap levels in calling microhabitats and acoustic parameters were observed, especially among pairs of closely related species. Analysis of null models showed a lack of structure in the spatial and acoustic niche, indicating the lack of detected competition. Results suggest that the calling activity of the species is strongly influenced by rainfall, moreover, the temporal partition appears to ensure coexistence. Finally, strong historical effects were detected in Leiuperinae, Leptodactylidae and in the partition Hylidae–Leptodactyliformes. 相似文献
947.
Frank A. Ocaña Alberto De Jesús-Navarrete Héctor A. Hernández-Arana 《Journal of Natural History》2018,52(33-34):2185-2196
Spatial distribution patterns of the ghost crab Ocypode quadrata were analysed using different approaches at one disturbed and two preserved reflective sandy beaches of the Mexican Caribbean. We used spatial correlation analysis to describe the across-shore distribution of O. quadrata and their patch dynamics by beach and sampling time. In addition, we analysed the across-shore variability of habitat extent of O. quadrata (habitat envelope) and its relation to human disturbance and beach features. The spatial structure of burrow density was consistent through time, showing a bimodal distribution with very low abundance in the mid distribution range and a discrete increment of burrows to landward. Nonetheless, the size of patches varied temporally for the three beaches. Burrow size increased from seaward to landward. The location of the first burrow and the habitat envelope varied among sampling times and beaches. The location of the first burrow is mostly mediated by the swash climate, while the habitat envelope is mainly controlled by the level of human disturbance. Despite the low number of disturbed and control beaches, our results suggest that the habitat envelope could be included in future studies when using ghost crabs as indicators of human disturbance. Polynomial models and variographic analysis proved to be useful tools to describe the across-shore distribution and patch dynamics of the ghost crab. 相似文献
948.
Rodrigo J. da Graça Fabrício H. Oda Flávia S. Lima Vinicius Guerra Priscilla G. Gambale Ricardo M. Takemoto 《Journal of Natural History》2017,51(13-14):705-729
Brazil has the richest anuran biodiversity in the world and many species have not yet been studied for parasites. One hundred and forty frogs belonging to 18 species (Rhinella schneideri, Dendropsophus aff. minutus, Dendropsophus nanus, Hypsiboas albopunctatus, Hypsiboas punctatus, Hypsiboas raniceps, Phyllomedusa tetraploidea, Pseudis platensis, Scinax fuscovarius, Trachycephalus typhonius, Leptodactylus chaquensis, Leptodactylus fuscus, Leptodactylus aff. latrans, Leptodactylus mystacinus, Leptodactylus podicipinus, Physalaemus cuvieri, Physalaemus nattereri and Elachistocleis bicolor) collected in aquatic habitats in forest remnants and surrounding agricultural landscapes in southern Brazil were examined for endoparasites. Twenty-four species of endoparasites were identified among 21 adult and three larval individuals: one species of Monogenea, Polystoma lopezromani; eight species of Digenea, Catadiscus marinholutzi, Catadiscus propinquus, Choledocystus simulans, Gordoderina sp., Neohaematoloechus neivai, Rauschiella lenti, Rauschiella linguatula, Rauschiella repandum; one species of Cestoda, Ophiotaenia sp.; one species of Acanthocephala, Centrorhyncus sp.; 12 species of Nematoda, Aplectana sp., Aplectana travassosi, Cosmocerca podicipinus, Raillietnema sp., Schrankiana formolusa, Falcaustra mascula, Oxyascaris oxyascaris, Ochoterenella digiticauda, Physaloptera sp., Brevimulticecum sp., Rhabdias sp., Parapharyngodon hylidae; and one species of Annelida, Dero (Allodero) lutzi. The endoparasite fauna found is constituted by generalist species. Two new records of occurrence in Brazil and 33 new host records are reported. 相似文献
949.
Some evidence indicates that in anuran amphibians, visual signalling can be important during social interactions such as territorial disputes among males, especially in diurnal species. The correct identification of a signal is not a trivial matter. A visual signal provides a visual cue during a social interaction, and to be effective it must elicit an immediate response in the receiver. We tested the hypothesis that visual displays in an agonistic context constitute aggressive signals, in three nocturnal species of Hylidae. We predicted that the production of visual displays would increase in the presence of a conspecific intruder male. Males of Hypsiboas raniceps, Dendropsophus nanus and Lysapsus limellum were submitted to two treatments: (1) Self Image, a reflection in a mirror, simulating the presence of an intruder; and (2) Control, a black rectangle covering the mirror. We observed three visual displays: vocal-sac display (inflate the vocal sac and maintain it inflated for some time), limb lifting (rapid up-and-down movements of one or more limbs), and toe/finger trembling (rapid up-and-down movements of one or more toes and/or fingers). This last display was observed only in H. raniceps males. Contrary to our hypothesis, the emission rates of all visual displays of the focal animals did not differ between treatments; and the behavioural response did not differ among species. Therefore, we suggest that these behaviours could not be used directly for communication in agonistic contexts, and may represent displacement activities (involuntary responses). Alternatively, an aggressive bimodal stimulus may be necessary to trigger a behavioural response by using visual signals during territory defence in these three species. 相似文献
950.
Wetlands are one of the most valuable natural resources, providing a number of ecosystem services and socio-economic values. Small ponds sustain a rich aquatic biodiversity and because of their short hydrological regimen and small size are excellent environments for population studies of microcrustaceans such as ostracods. This study describes the population dynamics of the Ostracoda fauna in three temporary shallow lakes during one hydroperiod in Argentine Patagonia. Three cosmopolitan species were determined: Cypris pubera, Tonnacypris lutaria and Eucypris virens. Among them, T. lutaria is here reported for the first time from the Neotropical region. Multivariate ordination techniques were used to examine the relationships among environmental variables and ostracod density on each sampling site. High values of conductivity, absorption at 320 nm (as a measure of dissolved organic matter), dissolved oxygen concentration, temperature and chlorophyll a concentration correlated positively with ostracod density. All the populations studied reproduced parthenogenetically, and the life cycles of E.virens and C. pubera were followed in detail by weekly sampling of their populations. The former displayed continuous reproduction, whereas the latter showed a multivoltine strategy. The life history of C. pubera was affected by the seasonality of the habitat. The development rate correlated positively with water temperature; conductivity and temperature had a positive effect on adult size in C. pubera, while conductivity had a negative effect on adult size in E. virens. In this study, we present the first data set on the development and life history of ostracods in Patagonian freshwater environments. However, several questions remain and encourage us to further investigate the relative importance of ostracods in food webs, as well as the importance of inter-specific interactions between ostracods and other taxa. 相似文献