全文获取类型
收费全文 | 41931篇 |
免费 | 87篇 |
国内免费 | 116篇 |
专业分类
系统科学 | 392篇 |
丛书文集 | 1022篇 |
教育与普及 | 107篇 |
理论与方法论 | 236篇 |
现状及发展 | 18788篇 |
研究方法 | 1598篇 |
综合类 | 19506篇 |
自然研究 | 485篇 |
出版年
2013年 | 213篇 |
2012年 | 527篇 |
2011年 | 1081篇 |
2010年 | 240篇 |
2008年 | 703篇 |
2007年 | 753篇 |
2006年 | 748篇 |
2005年 | 766篇 |
2004年 | 687篇 |
2003年 | 778篇 |
2002年 | 715篇 |
2001年 | 1286篇 |
2000年 | 1220篇 |
1999年 | 768篇 |
1992年 | 739篇 |
1991年 | 606篇 |
1990年 | 645篇 |
1989年 | 643篇 |
1988年 | 643篇 |
1987年 | 637篇 |
1986年 | 650篇 |
1985年 | 792篇 |
1984年 | 622篇 |
1983年 | 539篇 |
1982年 | 470篇 |
1981年 | 496篇 |
1980年 | 598篇 |
1979年 | 1302篇 |
1978年 | 1116篇 |
1977年 | 1114篇 |
1976年 | 825篇 |
1975年 | 872篇 |
1974年 | 1302篇 |
1973年 | 1052篇 |
1972年 | 1072篇 |
1971年 | 1326篇 |
1970年 | 1764篇 |
1969年 | 1385篇 |
1968年 | 1269篇 |
1967年 | 1329篇 |
1966年 | 1127篇 |
1965年 | 827篇 |
1964年 | 220篇 |
1959年 | 503篇 |
1958年 | 731篇 |
1957年 | 577篇 |
1956年 | 486篇 |
1955年 | 442篇 |
1954年 | 483篇 |
1948年 | 265篇 |
排序方式: 共有10000条查询结果,搜索用时 208 毫秒
381.
Summary The effect of dipyridamole on platelet phospholipids has been studied. After the platelet incubation with dipyridamole, a 38% reduction in the concentration of the sphingomyelin and a 21% increase in phosphatidyl choline were produced. 相似文献
382.
The hyperthermic effect of a bacterial pyrogen has been studied in rabbits pretreated or not with p-chlorophenylalanine or 5, 6-dihydroxytryptamine. The results obtained indicate that a selective reduction of cerebral 5-hydroxytryptamine levels by these drugs do not significantly affect pyrogen hypertermia. 相似文献
383.
V. R. Osório E Castro M. G. P. Vale A. P. Carvalho 《Cellular and molecular life sciences : CMLS》1976,32(4):424-426
Summary The effect of the antibiotic X-537A on the phosphorylated ATPase (EP) was investigated. The results show that X-537A depresses the level of EP which is dependent on the Ca2+ gradient, while the Ca2+-independent EP is not affected.
Acknowledgments. This work was supported by grants from the Instituto de Alta Cultura of the Portuguese Ministry of Education (No. CB/2) and the Calouste Gulbenkian Foundation. 相似文献
384.
Summary Adenylate kinase activity of intact mitochondria is strongly inhibited by Ap5A, i.e.p
1,p
5-Di (adenosine-5-) pentaphosphate, whereas oxidative phosphorylation is not affected. Therefore, Ap5A is a useful tool to distinguish between oxidative and non oxidative ATP generating reactions.Acknowledgment. The generous support of Prof. Dr.Walther Lamprecht is gratefully acknowledged. J. L. thanks the Stipendienfonds des Verbandes der Chemische Industrie for a scholarship. 相似文献
385.
A. J. Rein D. D. Saperstein S. H. Pines P. C. Radlick 《Cellular and molecular life sciences : CMLS》1976,32(10):1352-1354
Summary Using Raman spectroscopy, we demonstrate that low levels of -carotene, lycopene, and xanthophyll give rise to resonance enhanced bands in blood plasma. These results explain the significance of previously unidentified spectral maxima which have been related to the state of health of the blood donor. 相似文献
386.
W. Rittel R. Maier M. Brugger B. Kamber B. Riniker P. Sieber 《Cellular and molecular life sciences : CMLS》1976,32(2):246-248
Summary Assays of 8 synthetic analogues of human calcitonin in rats showed that their hypocalcaemic activity was drastically reduced by deletion of the C-terminal amide group, chain-shortening or opening of the disulphide ring, but unaffected or enhanced by modification of the N-terminal amino group.
II. vgl.R. Maier, B. Kamber, B. Riniker andW. Rittel, Hormon. Metab. Res.7, 511 (1975).
Die hier verwendete, abgekürzte Schreibweise für Peptide folgt den Empfehlungen der IUPAC-IUB Kommission für Biochemische Nomenklatur, J.B.C.247, 977 (1972). Weitere Abkürzungen: HCT, Human-Calcitonin; PCT, Schweinecalcitonin; Bmp, -Mercaptopropionsäure (Desaminocystein); NMet, Normethionin (S-Methylcystein); -OMe, Methylester. 相似文献
II. vgl.R. Maier, B. Kamber, B. Riniker andW. Rittel, Hormon. Metab. Res.7, 511 (1975).
Die hier verwendete, abgekürzte Schreibweise für Peptide folgt den Empfehlungen der IUPAC-IUB Kommission für Biochemische Nomenklatur, J.B.C.247, 977 (1972). Weitere Abkürzungen: HCT, Human-Calcitonin; PCT, Schweinecalcitonin; Bmp, -Mercaptopropionsäure (Desaminocystein); NMet, Normethionin (S-Methylcystein); -OMe, Methylester. 相似文献
387.
H. P. Striebel 《Cellular and molecular life sciences : CMLS》1976,32(4):457-458
Summary 4-isothiocyanato-4-nitrodiphenylamine was found to possess activity against intestinal nematodes in mice, against schistosomes in various hosts including primates and against two filarial species in the mongolian jird. Upon administration in a single oral dose it is equally effective againstS. haematobium, S. mansoni andS. japonicum. 相似文献
388.
J. Damas 《Cellular and molecular life sciences : CMLS》1976,32(6):725-727
Summary In normal rats, prostaglandin F2 is a potent vasoconstrictor. The corresponding systemic hypertension is progressively attenuated by tachyphylaxis, revealing a longlasting fall of blood pressure. Tachyphylaxis is accelerated by previous injection of arachidonic acid and bradykinin. The vasodepressive activity of PGF2 is inhibited by indomethacin.
Nous remercions vivement le docteurPike (Upjohn, Kalamazoo) qui nous a fourni gracieusement ces prostaglandines. 相似文献
Nous remercions vivement le docteurPike (Upjohn, Kalamazoo) qui nous a fourni gracieusement ces prostaglandines. 相似文献
389.
R. G. G. Andersson H. J. Arnqvist L. Lundholm 《Cellular and molecular life sciences : CMLS》1976,32(5):601-602
Summary The incorporation of leucice-14C into protein in bovine mesenteric arteries was augmented by cyclic GMP (10–3
M) and decreased by cyclic AMP (10–3
M). There was no effect of 5 AMP (10–3
M). The phosphodiesterase inhibiting drugs theophylline (10–3
M) and papaverine (5×10–5 g/ml) both decreased the leucine-14C incorporation.We are indebted to Mrs.Lena Burlin for hear assistance. Finacial support has been provided by the Swedish State Medical Research Council (No. 04X-101X-4498). 相似文献
390.
H. N. Nigg J. A. Svoboda M. J. Thompson S. R. Dutky J. N. Kaplanis W. E. Robbins 《Cellular and molecular life sciences : CMLS》1976,32(4):438-439
Summary An ecdysone 20-hydroxylase enzyme system that converts -ecdysone to 20-hydroxyecdysone was prepared from the midgut of the tobacco hornworm prepupa. This partially purified enzyme is NADPH dependent and is localized in the mitochondrial fraction of the midgut tissue. 相似文献