全文获取类型
收费全文 | 43896篇 |
免费 | 142篇 |
国内免费 | 291篇 |
专业分类
系统科学 | 532篇 |
丛书文集 | 1032篇 |
教育与普及 | 140篇 |
理论与方法论 | 243篇 |
现状及发展 | 17781篇 |
研究方法 | 1647篇 |
综合类 | 22133篇 |
自然研究 | 821篇 |
出版年
2013年 | 438篇 |
2012年 | 791篇 |
2011年 | 1637篇 |
2010年 | 503篇 |
2009年 | 453篇 |
2008年 | 950篇 |
2007年 | 1033篇 |
2006年 | 1075篇 |
2005年 | 1011篇 |
2004年 | 810篇 |
2003年 | 763篇 |
2002年 | 772篇 |
2001年 | 1242篇 |
2000年 | 1206篇 |
1999年 | 821篇 |
1992年 | 732篇 |
1991年 | 605篇 |
1990年 | 626篇 |
1989年 | 610篇 |
1988年 | 613篇 |
1987年 | 614篇 |
1986年 | 589篇 |
1985年 | 723篇 |
1984年 | 618篇 |
1983年 | 501篇 |
1982年 | 455篇 |
1981年 | 443篇 |
1980年 | 569篇 |
1979年 | 1232篇 |
1978年 | 1055篇 |
1977年 | 1069篇 |
1976年 | 755篇 |
1975年 | 855篇 |
1974年 | 1218篇 |
1973年 | 1058篇 |
1972年 | 1058篇 |
1971年 | 1307篇 |
1970年 | 1640篇 |
1969年 | 1289篇 |
1968年 | 1227篇 |
1967年 | 1295篇 |
1966年 | 1106篇 |
1965年 | 819篇 |
1959年 | 486篇 |
1958年 | 708篇 |
1957年 | 567篇 |
1956年 | 475篇 |
1955年 | 440篇 |
1954年 | 468篇 |
1948年 | 246篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
971.
972.
运动目标阴影在很大程度上会影响运动目标跟踪、行为识别的正确性和有效性.为此,文中提出了一种基于混合高斯模型和马尔科夫随机场的自适应阴影检测方法.该方法首先对混合高斯模型进行改进,使其可以自适应调整参数学习率以消除浅阴影;然后采用马尔科夫随机场综合邻域的空间依赖性信息进行精确的阴影检测.为了提高基于马尔科夫随机场的阴影检... 相似文献
973.
Fringe is a glycosyltransferase that modifies Notch 总被引:36,自引:0,他引:36
Moloney DJ Panin VM Johnston SH Chen J Shao L Wilson R Wang Y Stanley P Irvine KD Haltiwanger RS Vogt TF 《Nature》2000,406(6794):369-375
Notch receptors function in highly conserved intercellular signalling pathways that direct cell-fate decisions, proliferation and apoptosis in metazoans. Fringe proteins can positively and negatively modulate the ability of Notch ligands to activate the Notch receptor. Here we establish the biochemical mechanism of Fringe action. Drosophila and mammalian Fringe proteins possess a fucose-specific beta1,3 N-acetylglucosaminyltransferase activity that initiates elongation of O-linked fucose residues attached to epidermal growth factor-like sequence repeats of Notch. We obtained biological evidence that Fringe-dependent elongation of O-linked fucose on Notch modulates Notch signalling by using co-culture assays in mammalian cells and by expression of an enzymatically inactive Fringe mutant in Drosophila. The post-translational modification of Notch by Fringe represents a striking example of modulation of a signalling event by differential receptor glycosylation and identifies a mechanism that is likely to be relevant to other signalling pathways. 相似文献
974.
Normal faulting in central Tibet since at least 13.5 Myr ago 总被引:16,自引:0,他引:16
Blisniuk PM Hacker BR Glodny J Ratschbacher L Bi S Wu Z McWilliams MO Calvert A 《Nature》2001,412(6847):628-632
Tectonic models for the evolution of the Tibetan plateau interpret observed east-west thinning of the upper crust to be the result of either increased potential energy of elevated crust or geodynamic processes that may be unrelated to plateau formation. A key piece of information needed to evaluate these models is the timing of deformation within the plateau. The onset of normal faulting has been estimated to have commenced in southern Tibet between about 14 Myr ago and about 8 Myr ago and, in central Tibet, about 4 Myr ago. Here, however, we report a minimum age of approximately 13.5 Myr for the onset of graben formation in central Tibet, based on mineralization ages determined with Rb-Sr and 40Ar-39Ar data that post-date a major graben-bounding normal fault. These data, along with evidence for prolonged activity of normal faulting in this and other Tibetan grabens, support models that relate normal faulting to processes occurring beneath the plateau. Thinning of the upper crust is most plausibly the result of potential-energy increases resulting from spatially and temporally heterogeneous changes in thermal structure and density distribution within the crust and upper mantle beneath Tibet. This is supported by recent geophysical and geological data, which indicate that spatial heterogeneity exists in both the Tibetan crust and lithospheric mantle. 相似文献
975.
从虚拟企业的知识构成出发,阐述了建立知识库整合虚拟企业知识的必要性,探讨了建立虚拟企业知识贡献激励机制以获取对虚拟企业有贡献的知识的问题。 相似文献
976.
本文建立了同时考虑轴颈径向位移和歪斜时的滑动轴承动力学模型.对于这种模型,油膜力将扩展为四个广义力分量.文章将相应的动力系数矩阵分解为对称和反对称两部分并讨论其物理性质.然后,本文推导得出该模型的正交变换矩阵,在此基础上导得各向同性的动力系数矩阵表达式,并讨论了诸元素的物理意义.文章最后引入动力系数椭圆的概念以分析非对称动力系数矩阵的变换性质. 相似文献
977.
Metagenomic and functional analysis of hindgut microbiota of a wood-feeding higher termite 总被引:6,自引:0,他引:6
Warnecke F Luginbühl P Ivanova N Ghassemian M Richardson TH Stege JT Cayouette M McHardy AC Djordjevic G Aboushadi N Sorek R Tringe SG Podar M Martin HG Kunin V Dalevi D Madejska J Kirton E Platt D Szeto E Salamov A Barry K Mikhailova N Kyrpides NC Matson EG Ottesen EA Zhang X Hernández M Murillo C Acosta LG Rigoutsos I Tamayo G Green BD Chang C Rubin EM Mathur EJ Robertson DE Hugenholtz P Leadbetter JR 《Nature》2007,450(7169):560-565
From the standpoints of both basic research and biotechnology, there is considerable interest in reaching a clearer understanding of the diversity of biological mechanisms employed during lignocellulose degradation. Globally, termites are an extremely successful group of wood-degrading organisms and are therefore important both for their roles in carbon turnover in the environment and as potential sources of biochemical catalysts for efforts aimed at converting wood into biofuels. Only recently have data supported any direct role for the symbiotic bacteria in the gut of the termite in cellulose and xylan hydrolysis. Here we use a metagenomic analysis of the bacterial community resident in the hindgut paunch of a wood-feeding 'higher' Nasutitermes species (which do not contain cellulose-fermenting protozoa) to show the presence of a large, diverse set of bacterial genes for cellulose and xylan hydrolysis. Many of these genes were expressed in vivo or had cellulase activity in vitro, and further analyses implicate spirochete and fibrobacter species in gut lignocellulose degradation. New insights into other important symbiotic functions including H2 metabolism, CO2-reductive acetogenesis and N2 fixation are also provided by this first system-wide gene analysis of a microbial community specialized towards plant lignocellulose degradation. Our results underscore how complex even a 1-microl environment can be. 相似文献
978.
给出了钢管混凝土框架节点的试验结果,并采用有限元法对新型节点模式进行了应力场分析。介绍了该新型节点的设计方案及在实际工程中的应用。 相似文献
979.
980.